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miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1.

Lino Cardenas CL, Henaoui IS, Courcot E, Roderburg C, Cauffiez C, Aubert S, Copin MC, Wallaert B, Glowacki F, Dewaeles E, Milosevic J, Maurizio J, Tedrow J, Marcet B, Lo-Guidice JM, Kaminski N, Barbry P, Luedde T, Perrais M, Mari B, Pottier N.

PLoS Genet. 2013;9(2):e1003291. doi: 10.1371/journal.pgen.1003291. Epub 2013 Feb 14.


miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis.

Liu G, Friggeri A, Yang Y, Milosevic J, Ding Q, Thannickal VJ, Kaminski N, Abraham E.

J Exp Med. 2010 Aug 2;207(8):1589-97. doi: 10.1084/jem.20100035. Epub 2010 Jul 19.


miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis.

Yang S, Xie N, Cui H, Banerjee S, Abraham E, Thannickal VJ, Liu G.

FASEB J. 2012 Sep;26(9):3790-9. doi: 10.1096/fj.11-202366. Epub 2012 Jun 1. Retraction in: FASEB J. 2013 Feb;27(2):843.


miR-145 regulates myofibroblast differentiation and lung fibrosis.

Yang S, Cui H, Xie N, Icyuz M, Banerjee S, Antony VB, Abraham E, Thannickal VJ, Liu G.

FASEB J. 2013 Jun;27(6):2382-91. doi: 10.1096/fj.12-219493. Epub 2013 Mar 1.


Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis.

Dakhlallah D, Batte K, Wang Y, Cantemir-Stone CZ, Yan P, Nuovo G, Mikhail A, Hitchcock CL, Wright VP, Nana-Sinkam SP, Piper MG, Marsh CB.

Am J Respir Crit Care Med. 2013 Feb 15;187(4):397-405. doi: 10.1164/rccm.201205-0888OC. Epub 2013 Jan 10.


The deoxycholic acid targets miRNA-dependent CAC1 gene expression in multidrug resistance of human colorectal cancer.

Kong Y, Bai PS, Sun H, Nan KJ, Chen NZ, Qi XG.

Int J Biochem Cell Biol. 2012 Dec;44(12):2321-32. doi: 10.1016/j.biocel.2012.08.006. Epub 2012 Aug 10.


Participation of miR-200 in pulmonary fibrosis.

Yang S, Banerjee S, de Freitas A, Sanders YY, Ding Q, Matalon S, Thannickal VJ, Abraham E, Liu G.

Am J Pathol. 2012 Feb;180(2):484-93. doi: 10.1016/j.ajpath.2011.10.005. Epub 2011 Dec 20.


MicroRNA-199a-5p is associated with hypoxia-inducible factor-1α expression in lungs from patients with COPD.

Mizuno S, Bogaard HJ, Gomez-Arroyo J, Alhussaini A, Kraskauskas D, Cool CD, Voelkel NF.

Chest. 2012 Sep;142(3):663-72.


Profibrotic role of miR-154 in pulmonary fibrosis.

Milosevic J, Pandit K, Magister M, Rabinovich E, Ellwanger DC, Yu G, Vuga LJ, Weksler B, Benos PV, Gibson KF, McMillan M, Kahn M, Kaminski N.

Am J Respir Cell Mol Biol. 2012 Dec;47(6):879-87. doi: 10.1165/rcmb.2011-0377OC. Epub 2012 Oct 4.


[Identification of differently expressed microRNAs in keloid and pilot study on biological function of miR-199a-5p].

Wu ZY, Lu L, Guo XR, Zhang PH.

Zhonghua Zheng Xing Wai Ke Za Zhi. 2013 Jul;29(4):279-84. Chinese.


Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis.

Liang H, Gu Y, Li T, Zhang Y, Huangfu L, Hu M, Zhao D, Chen Y, Liu S, Dong Y, Li X, Lu Y, Yang B, Shan H.

Cell Death Dis. 2014 May 22;5:e1238. doi: 10.1038/cddis.2014.207.


MicroRNAs in idiopathic pulmonary fibrosis.

Pandit KV, Milosevic J, Kaminski N.

Transl Res. 2011 Apr;157(4):191-9. doi: 10.1016/j.trsl.2011.01.012. Epub 2011 Feb 4. Review.


miR-199a-5p silencing regulates the unfolded protein response in chronic obstructive pulmonary disease and α1-antitrypsin deficiency.

Hassan T, Carroll TP, Buckley PG, Cummins R, O'Neill SJ, McElvaney NG, Greene CM.

Am J Respir Crit Care Med. 2014 Feb 1;189(3):263-73. doi: 10.1164/rccm.201306-1151OC.


miR-29 is a major regulator of genes associated with pulmonary fibrosis.

Cushing L, Kuang PP, Qian J, Shao F, Wu J, Little F, Thannickal VJ, Cardoso WV, Lü J.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):287-94. doi: 10.1165/rcmb.2010-0323OC. Epub 2010 Oct 22.


Aortic carboxypeptidase-like protein (ACLP) enhances lung myofibroblast differentiation through transforming growth factor β receptor-dependent and -independent pathways.

Tumelty KE, Smith BD, Nugent MA, Layne MD.

J Biol Chem. 2014 Jan 31;289(5):2526-36. doi: 10.1074/jbc.M113.502617. Epub 2013 Dec 16.


PI3K p110γ overexpression in idiopathic pulmonary fibrosis lung tissue and fibroblast cells: in vitro effects of its inhibition.

Conte E, Gili E, Fruciano M, Korfei M, Fagone E, Iemmolo M, Lo Furno D, Giuffrida R, Crimi N, Guenther A, Vancheri C.

Lab Invest. 2013 May;93(5):566-76. doi: 10.1038/labinvest.2013.6. Epub 2013 Feb 25.


Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.

Smith MR, Gangireddy SR, Narala VR, Hogaboam CM, Standiford TJ, Christensen PJ, Kondapi AK, Reddy RC.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L616-25. doi: 10.1152/ajplung.00002.2009. Epub 2010 Jan 8.


Yin yang 1 is a novel regulator of pulmonary fibrosis.

Lin X, Sime PJ, Xu H, Williams MA, LaRussa L, Georas SN, Guo J.

Am J Respir Crit Care Med. 2011 Jun 15;183(12):1689-97. doi: 10.1164/rccm.201002-0232OC. Epub 2010 Dec 17.


microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress.

Dai BH, Geng L, Wang Y, Sui CJ, Xie F, Shen RX, Shen WF, Yang JM.

Cell Death Dis. 2013 Apr 18;4:e604. doi: 10.1038/cddis.2013.134.

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