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Items: 1 to 20 of 204

1.

Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort.

Harder MN, Ribel-Madsen R, Justesen JM, Sparsø T, Andersson EA, Grarup N, Jørgensen T, Linneberg A, Hansen T, Pedersen O.

J Clin Endocrinol Metab. 2013 Apr;98(4):E801-6. doi: 10.1210/jc.2012-4169. Epub 2013 Mar 1.

PMID:
23457408
2.

The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes.

Harder MN, Appel EV, Grarup N, Gjesing AP, Ahluwalia TS, Jørgensen T, Christensen C, Brandslund I, Linneberg A, Sørensen TI, Pedersen O, Hansen T.

PLoS One. 2015 Mar 23;10(3):e0120890. doi: 10.1371/journal.pone.0120890. eCollection 2015.

3.

Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes.

Matsuba R, Sakai K, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

PLoS One. 2015 May 7;10(5):e0126363. doi: 10.1371/journal.pone.0126363. eCollection 2015.

4.

Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.

Robiou-du-Pont S, Bonnefond A, Yengo L, Vaillant E, Lobbens S, Durand E, Weill J, Lantieri O, Balkau B, Charpentier G, Marre M, Froguel P, Meyre D.

Int J Obes (Lond). 2013 Jul;37(7):980-5. doi: 10.1038/ijo.2012.175. Epub 2012 Oct 23.

PMID:
23090577
5.

The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals.

Banasik K, Hollensted M, Andersson E, Sparsø T, Sandbaek A, Lauritzen T, Jørgensen T, Witte DR, Pedersen O, Hansen T.

BMC Med Genet. 2012 Feb 12;13:10. doi: 10.1186/1471-2350-13-10.

6.

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

Grarup N, Andersen G, Krarup NT, Albrechtsen A, Schmitz O, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen O.

Diabetes. 2008 Sep;57(9):2534-40. doi: 10.2337/db08-0436. Epub 2008 Jun 20.

7.

Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects.

Grarup N, Stender-Petersen KL, Andersson EA, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

Diabetes. 2008 Apr;57(4):1136-42. doi: 10.2337/db07-1534. Epub 2008 Jan 11.

8.

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

Diabetes. 2009 Jun;58(6):1450-6. doi: 10.2337/db08-1660. Epub 2009 Mar 26.

9.

Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease.

de Miguel-Yanes JM, Manning AK, Shrader P, McAteer JB, Goel A, Hamsten A; PROCARDIS, Fox CS, Florez JC, Dupuis J, Meigs JB.

Obesity (Silver Spring). 2011 Oct;19(10):2031-7. doi: 10.1038/oby.2011.135. Epub 2011 Jun 2.

10.

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, Albrechtsen A, Clausen JO, Rasmussen SS, Jørgensen T, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

Diabetes. 2007 Dec;56(12):3105-11. Epub 2007 Sep 7.

11.

The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load.

Hornbak M, Banasik K, Justesen JM, Krarup NT, Sandholt CH, Andersson Å, Sandbæk A, Lauritzen T, Pisinger C, Witte DR, Sørensen TA, Pedersen O, Hansen T.

BMC Med Genet. 2011 Jan 6;12:4. doi: 10.1186/1471-2350-12-4.

12.

Cross-sectional and longitudinal replication analyses of genome-wide association loci of type 2 diabetes in Han Chinese.

Zhao Q, Xiao J, He J, Zhang X, Hong J, Kong X, Mills KT, Weng J, Jia W, Yang W.

PLoS One. 2014 Mar 17;9(3):e91790. doi: 10.1371/journal.pone.0091790. eCollection 2014.

13.

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.

Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T.

Diabetologia. 2008 Sep;51(9):1646-52. doi: 10.1007/s00125-008-1064-2. Epub 2008 Jun 21.

PMID:
18568334
14.

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

Boesgaard TW, Gjesing AP, Grarup N, Rutanen J, Jansson PA, Hribal ML, Sesti G, Fritsche A, Stefan N, Staiger H, Häring H, Smith U, Laakso M, Pedersen O, Hansen T; EUGENE2 Consortium.

PLoS One. 2009 Sep 30;4(9):e7236. doi: 10.1371/journal.pone.0007236.

15.

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, Assimes TL, Hao K, Yang X, Lecoeur C, Barroso I, Bonnycastle LL, Böttcher Y, Bumpstead S, Chines PS, Erdos MR, Graessler J, Kovacs P, Morken MA, Narisu N, Payne F, Stancakova A, Swift AJ, Tönjes A, Bornstein SR, Cauchi S, Froguel P, Meyre D, Schwarz PE, Häring HU, Smith U, Boehnke M, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, Quertemous T, Lind L, Hansen T, Pedersen O, Walker M, Pfeiffer AF, Spranger J, Stumvoll M, Meigs JB, Wareham NJ, Kuusisto J, Laakso M, Langenberg C, Dupuis J, Watanabe RM, Florez JC, Ingelsson E, McCarthy MI, Prokopenko I; MAGIC Investigators.

Diabetes. 2014 Jun;63(6):2158-71. doi: 10.2337/db13-0949. Epub 2013 Dec 2. Review.

16.

Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function.

Staiger H, Machicao F, Schäfer SA, Kirchhoff K, Kantartzis K, Guthoff M, Silbernagel G, Stefan N, Häring HU, Fritsche A.

PLoS One. 2008;3(12):e3962. doi: 10.1371/journal.pone.0003962. Epub 2008 Dec 17.

17.

Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.

Rathcke CN, Holmkvist J, Jørgensen T, Borch-Johnsen K, Hansen T, Pedersen OB, Vestergaard H.

PLoS One. 2009;4(5):e5469. doi: 10.1371/journal.pone.0005469. Epub 2009 May 7.

18.

Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.

Weyrich P, Staiger H, Stancáková A, Schäfer SA, Kirchhoff K, Ullrich S, Ranta F, Gallwitz B, Stefan N, Machicao F, Kuusisto J, Laakso M, Fritsche A, Häring HU.

BMC Med Genet. 2009 Aug 14;10:77. doi: 10.1186/1471-2350-10-77.

19.

Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals.

Xu K, Jiang L, Zhang M, Zheng X, Gu Y, Wang Z, Cai Y, Dai H, Shi Y, Zheng S, Chen Y, Ji L, Xu X, Chen H, Sun M, Yang T.

Medicine (Baltimore). 2016 May;95(19):e3604. doi: 10.1097/MD.0000000000003604.

20.

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

Staiger H, Machicao F, Kantartzis K, Schäfer SA, Kirchhoff K, Guthoff M, Silbernagel G, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008 Aug 20;3(8):e3019. doi: 10.1371/journal.pone.0003019.

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