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Results: 1 to 20 of 111

1.

Thiopurine treatment in patients with Crohn's disease leads to a selective reduction of an effector cytotoxic gene expression signature revealed by whole-genome expression profiling.

Bouma G, Baggen JM, van Bodegraven AA, Mulder CJ, Kraal G, Zwiers A, Horrevoets AJ, van der Pouw Kraan CT.

Mol Immunol. 2013 Jul;54(3-4):472-81. doi: 10.1016/j.molimm.2013.01.015. Epub 2013 Feb 27.

PMID:
23454163
[PubMed - indexed for MEDLINE]
2.

Defective IL-1A expression in patients with Crohn's disease is related to attenuated MAP3K4 signaling.

van der Pouw Kraan CT, Baggen JM, van Bodegraven AA, Mulder CJ, Zwiers A, Geerts D, Kraal G, Horrevoets AJ, Bouma G.

Hum Immunol. 2012 Sep;73(9):912-9. doi: 10.1016/j.humimm.2012.06.004. Epub 2012 Jun 22.

PMID:
22732089
[PubMed - indexed for MEDLINE]
3.

"In vitro" azathioprine-induced changes in peripheral T cell apoptosis and IFN-γ production associate with drug response in patients with Crohn's Disease.

Cossu A, Biancone L, Ascolani M, Pallone F, Boirivant M.

J Crohns Colitis. 2013 Jul;7(6):441-50. doi: 10.1016/j.crohns.2012.06.020. Epub 2012 Jul 26.

PMID:
22840925
[PubMed - indexed for MEDLINE]
4.

Outcome predictors for thiopurine maintenance therapy in patients with Crohn's disease.

Park JJ, Cheon JH, Hong SP, Kim TI, Kim WH.

Dig Dis Sci. 2012 Jan;57(1):133-41. doi: 10.1007/s10620-011-1955-9. Epub 2011 Nov 6.

PMID:
22057283
[PubMed - indexed for MEDLINE]
5.

The effect of 6-mercaptopurine on natural killer-cell activities in Crohn's disease.

Brogan M, Hiserodt J, Oliver M, Stevens R, Korelitz B, Targan S.

J Clin Immunol. 1985 May;5(3):204-11.

PMID:
3874211
[PubMed - indexed for MEDLINE]
6.

Mutagenicity and potential carcinogenicity of thiopurine treatment in patients with inflammatory bowel disease.

Nguyen T, Vacek PM, O'Neill P, Colletti RB, Finette BA.

Cancer Res. 2009 Sep 1;69(17):7004-12. doi: 10.1158/0008-5472.CAN-09-0451. Epub 2009 Aug 25.

PMID:
19706768
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genome wide transcriptional analysis of resting and IL2 activated human natural killer cells: gene expression signatures indicative of novel molecular signaling pathways.

Dybkaer K, Iqbal J, Zhou G, Geng H, Xiao L, Schmitz A, d'Amore F, Chan WC.

BMC Genomics. 2007 Jul 10;8:230.

PMID:
17623099
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

Thiopurine effectiveness in patients with Crohn's disease: a study of genetic and clinical predictive factors.

Koifman E, Karban A, Mazor Y, Chermesh I, Waterman M, Almog R, Ben-Horin S, Eliakim R, Krivoy N, Efrati E, Chowers Y.

Inflamm Bowel Dis. 2013 Jul;19(8):1639-44. doi: 10.1097/MIB.0b013e31828828d3.

PMID:
23669401
[PubMed - indexed for MEDLINE]
10.

The impact of thiopurines on the risk of surgical recurrence in patients with Crohn's disease after first intestinal surgery.

Papay P, Reinisch W, Ho E, Gratzer C, Lissner D, Herkner H, Riss S, Dejaco C, Miehsler W, Vogelsang H, Novacek G.

Am J Gastroenterol. 2010 May;105(5):1158-64. doi: 10.1038/ajg.2009.673. Epub 2009 Dec 15.

PMID:
20010925
[PubMed - indexed for MEDLINE]
11.

Peripheral monocyte functions and activation in patients with quiescent Crohn's disease.

Schwarzmaier D, Foell D, Weinhage T, Varga G, Däbritz J.

PLoS One. 2013 Apr 26;8(4):e62761. doi: 10.1371/journal.pone.0062761. Print 2013.

PMID:
23658649
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Quantitative and functional evaluation of innate immune responses in patients with common variable immunodeficiency.

Trujillo CM, Muskus C, Arango J, Patiño PJ, Montoya CJ.

J Investig Allergol Clin Immunol. 2011;21(3):207-15.

PMID:
21548449
[PubMed - indexed for MEDLINE]
Free Article
13.

Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells.

Chinen H, Matsuoka K, Sato T, Kamada N, Okamoto S, Hisamatsu T, Kobayashi T, Hasegawa H, Sugita A, Kinjo F, Fujita J, Hibi T.

Gastroenterology. 2007 Aug;133(2):559-73. Epub 2007 May 21.

PMID:
17681176
[PubMed - indexed for MEDLINE]
14.

CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions.

Allez M, Tieng V, Nakazawa A, Treton X, Pacault V, Dulphy N, Caillat-Zucman S, Paul P, Gornet JM, Douay C, Ravet S, Tamouza R, Charron D, Lémann M, Mayer L, Toubert A.

Gastroenterology. 2007 Jun;132(7):2346-58. Epub 2007 Mar 16.

PMID:
17570210
[PubMed - indexed for MEDLINE]
15.

Transcriptional profiling of immune genes in bovine monocyte-derived macrophages exposed to bacterial antigens.

Taraktsoglou M, Szalabska U, Magee DA, Browne JA, Sweeney T, Gormley E, MacHugh DE.

Vet Immunol Immunopathol. 2011 Mar 15;140(1-2):130-9. doi: 10.1016/j.vetimm.2010.12.002. Epub 2010 Dec 10.

PMID:
21242003
[PubMed - indexed for MEDLINE]
16.

Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease.

Prefontaine E, Macdonald JK, Sutherland LR.

Cochrane Database Syst Rev. 2009 Oct 7;(4):CD000545. doi: 10.1002/14651858.CD000545.pub2. Review. Update in: Cochrane Database Syst Rev. 2010;(6):CD000545.

PMID:
19821270
[PubMed - indexed for MEDLINE]
17.

Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease.

Prefontaine E, Macdonald JK, Sutherland LR.

Cochrane Database Syst Rev. 2010 Jun 16;(6):CD000545. doi: 10.1002/14651858.CD000545.pub3. Review. Update in: Cochrane Database Syst Rev. 2013;4:CD000545.

PMID:
20556747
[PubMed - indexed for MEDLINE]
18.

Defective tumor necrosis factor release from Crohn's disease macrophages in response to Toll-like receptor activation: relationship to phenotype and genome-wide association susceptibility loci.

Sewell GW, Rahman FZ, Levine AP, Jostins L, Smith PJ, Walker AP, Bloom SL, Segal AW, Smith AM.

Inflamm Bowel Dis. 2012 Nov;18(11):2120-7. doi: 10.1002/ibd.22952. Epub 2012 Mar 20.

PMID:
22434667
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset.

Barakonyi A, Rabot M, Marie-Cardine A, Aguerre-Girr M, Polgar B, Schiavon V, Bensussan A, Le Bouteiller P.

J Immunol. 2004 Nov 1;173(9):5349-54.

PMID:
15494480
[PubMed - indexed for MEDLINE]
Free Article
20.

Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines.

Thomas CW, Myhre GM, Tschumper R, Sreekumar R, Jelinek D, McKean DJ, Lipsky JJ, Sandborn WJ, Egan LJ.

J Pharmacol Exp Ther. 2005 Feb;312(2):537-45. Epub 2004 Sep 23.

PMID:
15388785
[PubMed - indexed for MEDLINE]
Free Article

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