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Results: 1 to 20 of 99

1.

Computational, structural, and kinetic evidence that Vibrio vulnificus FrsA is not a cofactor-independent pyruvate decarboxylase.

Kellett WF, Brunk E, Desai BJ, Fedorov AA, Almo SC, Gerlt JA, Rothlisberger U, Richards NG.

Biochemistry. 2013 Mar 19;52(11):1842-4. doi: 10.1021/bi400093y. Epub 2013 Mar 5.

PMID:
23452154
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

FrsA functions as a cofactor-independent decarboxylase to control metabolic flux.

Lee KJ, Jeong CS, An YJ, Lee HJ, Park SJ, Seok YJ, Kim P, Lee JH, Lee KH, Cha SS.

Nat Chem Biol. 2011 May 29;7(7):434-6. doi: 10.1038/nchembio.589.

PMID:
21623357
[PubMed - indexed for MEDLINE]
3.

Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis .

Pei XY, Erixon KM, Luisi BF, Leeper FJ.

Biochemistry. 2010 Mar 2;49(8):1727-36. doi: 10.1021/bi901864j.

PMID:
20099870
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The structural basis of substrate activation in yeast pyruvate decarboxylase. A crystallographic and kinetic study.

Lu G, Dobritzsch D, Baumann S, Schneider G, König S.

Eur J Biochem. 2000 Feb;267(3):861-8.

PMID:
10651824
[PubMed - indexed for MEDLINE]
Free Article
6.

Pyruvate decarboxylase from Kluyveromyces lactis. An enzyme with an extraordinary substrate activation behaviour.

Krieger F, Spinka M, Golbik R, Hübner G, König S.

Eur J Biochem. 2002 Jul;269(13):3256-63.

PMID:
12084066
[PubMed - indexed for MEDLINE]
Free Article
7.

Cofactor activation and substrate binding in pyruvate decarboxylase. Insights into the reaction mechanism from molecular dynamics simulations.

Lie MA, Celik L, Jørgensen KA, Schiøtt B.

Biochemistry. 2005 Nov 15;44(45):14792-806.

PMID:
16274227
[PubMed - indexed for MEDLINE]
8.

Computational studies on the decarboxylation of 2-(1-carboxy-1-hydroxyethyl)-3,4-dimethylthiazolium dipolar ion, an analog of the complex of pyruvic acid and coenzyme of the pyruvate decarboxylase.

Nakajima Y, Sakagishi Y, Shiibashi M, Suzuki Y, Kato H.

Biochem Biophys Res Commun. 1993 Aug 31;195(1):449-54.

PMID:
8363620
[PubMed - indexed for MEDLINE]
9.

Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.

Balakrishnan A, Gao Y, Moorjani P, Nemeria NS, Tittmann K, Jordan F.

J Am Chem Soc. 2012 Feb 29;134(8):3873-85. doi: 10.1021/ja211139c. Epub 2012 Feb 17.

PMID:
22300533
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylases.

Dobritzsch D, König S, Schneider G, Lu G.

J Biol Chem. 1998 Aug 7;273(32):20196-204.

PMID:
9685367
[PubMed - indexed for MEDLINE]
Free Article
11.

Comparison of pyruvate decarboxylases from Saccharomyces cerevisiae and Komagataella pastoris (Pichia pastoris).

Agarwal PK, Uppada V, Noronha SB.

Appl Microbiol Biotechnol. 2013 Nov;97(21):9439-49. doi: 10.1007/s00253-013-4758-4. Epub 2013 Feb 20.

PMID:
23423327
[PubMed - indexed for MEDLINE]
12.

Engineering the substrate binding site of benzoylformate decarboxylase.

Yep A, McLeish MJ.

Biochemistry. 2009 Sep 8;48(35):8387-95. doi: 10.1021/bi9008402.

PMID:
19621900
[PubMed - indexed for MEDLINE]
13.

Mechanistic insight into the catalytic activity of ββα-metallonucleases from computer simulations: Vibrio vulnificus periplasmic nuclease as a test case.

Bueren-Calabuig JA, Coderch C, Rico E, Jiménez-Ruiz A, Gago F.

Chembiochem. 2011 Nov 25;12(17):2615-22. doi: 10.1002/cbic.201100485. Epub 2011 Oct 6.

PMID:
22114054
[PubMed - indexed for MEDLINE]
14.

Catalytically active filaments - pyruvate decarboxylase from Neurospora crassa. pH-controlled oligomer structure and catalytic function.

Hüttl S, Fiebig J, Kutter S, Hause G, Lilie H, Spinka M, König S.

FEBS J. 2012 Jan;279(2):275-84. doi: 10.1111/j.1742-4658.2011.08421.x. Epub 2011 Dec 9.

PMID:
22077835
[PubMed - indexed for MEDLINE]
15.

The influence of protein concentration on oligomer structure and catalytic function of two pyruvate decarboxylases.

Kutter S, Spinka M, Koch MH, König S.

Protein J. 2007 Dec;26(8):585-91.

PMID:
17805949
[PubMed - indexed for MEDLINE]
16.

Reaction mechanism of the heterotetrameric (alpha2beta2) E1 component of 2-oxo acid dehydrogenase multienzyme complexes.

Fries M, Jung HI, Perham RN.

Biochemistry. 2003 Jun 17;42(23):6996-7002.

PMID:
12795594
[PubMed - indexed for MEDLINE]
17.

Reactivity at the substrate activation site of yeast pyruvate decarboxylase: inhibition by distortion of domain interactions.

Baburina I, Dikdan G, Guo F, Tous GI, Root B, Jordan F.

Biochemistry. 1998 Feb 3;37(5):1245-55.

PMID:
9477950
[PubMed - indexed for MEDLINE]
18.

The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis. Implications for the substrate activation mechanism of this enzyme.

Kutter S, Wille G, Relle S, Weiss MS, Hübner G, König S.

FEBS J. 2006 Sep;273(18):4199-209.

PMID:
16939618
[PubMed - indexed for MEDLINE]
19.

The role of His113 and His114 in pyruvate decarboxylase from Zymomonas mobilis.

Schenk G, Leeper FJ, England R, Nixon PF, Duggleby RG.

Eur J Biochem. 1997 Aug 15;248(1):63-71.

PMID:
9310361
[PubMed - indexed for MEDLINE]
Free Article

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