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Items: 1 to 20 of 82

1.

IDH1-associated primary glioblastoma in young adults displays differential patterns of tumour and vascular morphology.

Popov S, Jury A, Laxton R, Doey L, Kandasamy N, Al-Sarraj S, Jürgensmeier JM, Jones C.

PLoS One. 2013;8(2):e56328. doi: 10.1371/journal.pone.0056328. Epub 2013 Feb 22.

2.

Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants.

Joseph NM, Phillips J, Dahiya S, M Felicella M, Tihan T, Brat DJ, Perry A.

Mod Pathol. 2013 Mar;26(3):315-26. doi: 10.1038/modpathol.2012.173. Epub 2012 Oct 5.

3.

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas.

Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A.

Acta Neuropathol. 2010 Dec;120(6):707-18. doi: 10.1007/s00401-010-0781-z. Epub 2010 Nov 19.

PMID:
21088844
4.

Distinct phenotypic differences associated with differential amplification of receptor tyrosine kinase genes at 4q12 in glioblastoma.

Burford A, Little SE, Jury A, Popov S, Laxton R, Doey L, Al-Sarraj S, Jürgensmeier JM, Jones C.

PLoS One. 2013 Aug 21;8(8):e71777. doi: 10.1371/journal.pone.0071777. eCollection 2013.

5.

Analysis of isocitrate dehydrogenase 1 mutation in 97 patients with glioma.

Zhou YX, Wang JX, Feng M, Sun CM, Sun T, Chen GL, Du ZW.

J Mol Neurosci. 2012 Jul;47(3):442-7. doi: 10.1007/s12031-011-9681-5. Epub 2011 Nov 24.

PMID:
22113362
6.

The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

Bleeker FE, Atai NA, Lamba S, Jonker A, Rijkeboer D, Bosch KS, Tigchelaar W, Troost D, Vandertop WP, Bardelli A, Van Noorden CJ.

Acta Neuropathol. 2010 Apr;119(4):487-94. doi: 10.1007/s00401-010-0645-6. Epub 2010 Feb 4.

7.

Vascular patterns in glioblastoma influence clinical outcome and associate with variable expression of angiogenic proteins: evidence for distinct angiogenic subtypes.

Birner P, Piribauer M, Fischer I, Gatterbauer B, Marosi C, Ambros PF, Ambros IM, Bredel M, Oberhuber G, Rössler K, Budka H, Harris AL, Hainfellner JA.

Brain Pathol. 2003 Apr;13(2):133-43.

PMID:
12744467
8.

Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma.

Song X, Andrew Allen R, Terence Dunn S, Fung KM, Farmer P, Gandhi S, Ranjan T, Demopoulos A, Symons M, Schulder M, Li JY.

Int J Clin Exp Pathol. 2011;4(7):651-60. Epub 2011 Sep 17.

9.

Expression of pERK and pAKT in human astrocytomas: correlation with IDH1-R132H presence, vascular endothelial growth factor, microvascular characteristics and clinical outcome.

Saetta AA, Levidou G, El-Habr EA, Panayotidis I, Samaras V, Thymara I, Sakellariou S, Boviatsis E, Patsouris E, Korkolopoulou P.

Virchows Arch. 2011 Jun;458(6):749-59. doi: 10.1007/s00428-011-1074-1. Epub 2011 Apr 15.

PMID:
21494763
10.

Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

Lai A, Kharbanda S, Pope WB, Tran A, Solis OE, Peale F, Forrest WF, Pujara K, Carrillo JA, Pandita A, Ellingson BM, Bowers CW, Soriano RH, Schmidt NO, Mohan S, Yong WH, Seshagiri S, Modrusan Z, Jiang Z, Aldape KD, Mischel PS, Liau LM, Escovedo CJ, Chen W, Nghiemphu PL, James CD, Prados MD, Westphal M, Lamszus K, Cloughesy T, Phillips HS.

J Clin Oncol. 2011 Dec 1;29(34):4482-90. doi: 10.1200/JCO.2010.33.8715. Epub 2011 Oct 24.

11.

Histopathological malignant progression of grade II and III gliomas correlated with IDH1/2 mutation status.

Ohno M, Narita Y, Miyakita Y, Okita Y, Matsushita Y, Yoshida A, Fukushima S, Ichimura K, Kayama T, Shibui S.

Brain Tumor Pathol. 2012 Oct;29(4):183-91. doi: 10.1007/s10014-012-0113-1. Epub 2012 Jul 13.

PMID:
22790483
12.

Relationship between tumor enhancement, edema, IDH1 mutational status, MGMT promoter methylation, and survival in glioblastoma.

Carrillo JA, Lai A, Nghiemphu PL, Kim HJ, Phillips HS, Kharbanda S, Moftakhar P, Lalaezari S, Yong W, Ellingson BM, Cloughesy TF, Pope WB.

AJNR Am J Neuroradiol. 2012 Aug;33(7):1349-55. doi: 10.3174/ajnr.A2950. Epub 2012 Feb 9.

13.

Pathologic diversity of glioneuronal tumor with neuropil-like islands: a histological and immunohistochemical study with a special reference to isocitrate dehydrogenase 1 (IDH1) in 5 cases.

Ishizawa K, Hirose T, Sugiyama K, Kageji T, Nobusawa S, Homma T, Komori T, Sasaki A.

Clin Neuropathol. 2012 Mar-Apr;31(2):67-76.

PMID:
22385787
14.

Clinicopathological features and molecular analysis of primary glioblastomas in Moroccan patients.

Hilmani S, Abidi O, Benrahma H, Karkouri M, Sahraoui S, El Azhari A, Barakat A.

J Mol Neurosci. 2013 Mar;49(3):567-73. doi: 10.1007/s12031-012-9868-4. Epub 2012 Aug 4.

PMID:
22865003
15.

IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas.

Nobusawa S, Watanabe T, Kleihues P, Ohgaki H.

Clin Cancer Res. 2009 Oct 1;15(19):6002-7. doi: 10.1158/1078-0432.CCR-09-0715. Epub 2009 Sep 15.

16.

Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China.

Yan W, Zhang W, You G, Bao Z, Wang Y, Liu Y, Kang C, You Y, Wang L, Jiang T.

PLoS One. 2012;7(1):e30339. doi: 10.1371/journal.pone.0030339. Epub 2012 Jan 23.

17.

Genetic profile of astrocytic and oligodendroglial gliomas.

Ohgaki H, Kleihues P.

Brain Tumor Pathol. 2011 Jul;28(3):177-83. doi: 10.1007/s10014-011-0029-1. Epub 2011 Mar 26. Review.

PMID:
21442241
18.

Correlation among pathology, genotype, and patient outcomes in glioblastoma.

Homma T, Fukushima T, Vaccarella S, Yonekawa Y, Di Patre PL, Franceschi S, Ohgaki H.

J Neuropathol Exp Neurol. 2006 Sep;65(9):846-54.

19.

Characterization of molecular genetic alterations in GBMs highlights a distinctive molecular profile in young adults.

Jha P, Suri V, Singh G, Jha P, Purkait S, Pathak P, Sharma V, Sharma MC, Suri A, Gupta D, Mahapatra AK, Sarkar C.

Diagn Mol Pathol. 2011 Dec;20(4):225-32. doi: 10.1097/PDM.0b013e31821c30bc.

PMID:
22089350
20.

Phosphorylated 4E-binding protein 1 (p-4E-BP1): a novel prognostic marker in human astrocytomas.

Korkolopoulou P, Levidou G, El-Habr EA, Piperi C, Adamopoulos C, Samaras V, Boviatsis E, Thymara I, Trigka EA, Sakellariou S, Kavantzas N, Patsouris E, Saetta AA.

Histopathology. 2012 Aug;61(2):293-305. doi: 10.1111/j.1365-2559.2012.04236.x. Epub 2012 Jun 13.

PMID:
22690797
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