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Results: 1 to 20 of 148

1.

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.

Duplan E, Giaime E, Viotti J, Sévalle J, Corti O, Brice A, Ariga H, Qi L, Checler F, Alves da Costa C.

J Cell Sci. 2013 May 1;126(Pt 9):2124-33. doi: 10.1242/jcs.127340. Epub 2013 Feb 27.

PMID:
23447676
[PubMed - indexed for MEDLINE]
Free Article
2.

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress.

Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, Mizuno Y, Dawson TM, Dawson VL.

Hum Mol Genet. 2005 Jan 1;14(1):71-84. Epub 2004 Nov 3.

PMID:
15525661
[PubMed - indexed for MEDLINE]
Free Article
3.

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.

Xiong H, Wang D, Chen L, Choo YS, Ma H, Tang C, Xia K, Jiang W, Ronai Z, Zhuang X, Zhang Z.

J Clin Invest. 2009 Mar;119(3):650-60. doi: 10.1172/JCI37617. Epub 2009 Feb 23.

PMID:
19229105
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease.

Dodson MW, Guo M.

Curr Opin Neurobiol. 2007 Jun;17(3):331-7. Epub 2007 May 11. Review.

PMID:
17499497
[PubMed - indexed for MEDLINE]
5.

The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering.

Ottolini D, Calì T, Negro A, Brini M.

Hum Mol Genet. 2013 Jun 1;22(11):2152-68. doi: 10.1093/hmg/ddt068. Epub 2013 Feb 14.

PMID:
23418303
[PubMed - indexed for MEDLINE]
Free Article
6.

Parkin: much more than a simple ubiquitin ligase.

Alves da Costa C, Checler F.

Neurodegener Dis. 2012;10(1-4):49-51. doi: 10.1159/000332803. Epub 2011 Dec 23. Review.

PMID:
22204976
[PubMed - indexed for MEDLINE]
7.

Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner.

Kato I, Maita H, Takahashi-Niki K, Saito Y, Noguchi N, Iguchi-Ariga SM, Ariga H.

Mol Cell Biol. 2013 Jan;33(2):340-59. doi: 10.1128/MCB.01350-12. Epub 2012 Nov 12.

PMID:
23149933
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Airway epithelial inflammation-induced endoplasmic reticulum Ca2+ store expansion is mediated by X-box binding protein-1.

Martino ME, Olsen JC, Fulcher NB, Wolfgang MC, O'Neal WK, Ribeiro CM.

J Biol Chem. 2009 May 29;284(22):14904-13. doi: 10.1074/jbc.M809180200. Epub 2009 Mar 25.

PMID:
19321437
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line.

Hu MC, Gong HY, Lin GH, Hu SY, Chen MH, Huang SJ, Liao CF, Wu JL.

Biochem Biophys Res Commun. 2007 Aug 3;359(3):778-83. Epub 2007 Jun 4.

PMID:
17560942
[PubMed - indexed for MEDLINE]
10.

DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3.

Shinbo Y, Taira T, Niki T, Iguchi-Ariga SM, Ariga H.

Int J Oncol. 2005 Mar;26(3):641-8.

PMID:
15703819
[PubMed - indexed for MEDLINE]
11.

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.

da Costa CA, Sunyach C, Giaime E, West A, Corti O, Brice A, Safe S, Abou-Sleiman PM, Wood NW, Takahashi H, Goldberg MS, Shen J, Checler F.

Nat Cell Biol. 2009 Nov;11(11):1370-5. doi: 10.1038/ncb1981. Epub 2009 Oct 4.

PMID:
19801972
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway?

Fitzgerald JC, Plun-Favreau H.

FEBS J. 2008 Dec;275(23):5758-66. doi: 10.1111/j.1742-4658.2008.06708.x. Review.

PMID:
19021753
[PubMed - indexed for MEDLINE]
13.

Protein degradation in Parkinson disease revisited: it's complex.

Li H, Guo M.

J Clin Invest. 2009 Mar;119(3):442-5.

PMID:
19306499
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway.

Im JY, Lee KW, Woo JM, Junn E, Mouradian MM.

Hum Mol Genet. 2012 Jul 1;21(13):3013-24. doi: 10.1093/hmg/dds131. Epub 2012 Apr 5.

PMID:
22492997
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.

Thomas KJ, McCoy MK, Blackinton J, Beilina A, van der Brug M, Sandebring A, Miller D, Maric D, Cedazo-Minguez A, Cookson MR.

Hum Mol Genet. 2011 Jan 1;20(1):40-50. doi: 10.1093/hmg/ddq430. Epub 2010 Oct 11.

PMID:
20940149
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.

Giaime E, Sunyach C, Druon C, Scarzello S, Robert G, Grosso S, Auberger P, Goldberg MS, Shen J, Heutink P, Pouysségur J, Pagès G, Checler F, Alves da Costa C.

Cell Death Differ. 2010 Jan;17(1):158-69. doi: 10.1038/cdd.2009.116. Epub .

PMID:
19680261
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity.

Viotti J, Duplan E, Caillava C, Condat J, Goiran T, Giordano C, Marie Y, Idbaih A, Delattre JY, Honnorat J, Checler F, Alves da Costa C.

Oncogene. 2014 Apr 3;33(14):1764-75. doi: 10.1038/onc.2013.124. Epub 2013 May 6.

PMID:
23644658
[PubMed - indexed for MEDLINE]
18.

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6.

Olzmann JA, Li L, Chudaev MV, Chen J, Perez FA, Palmiter RD, Chin LS.

J Cell Biol. 2007 Sep 10;178(6):1025-38.

PMID:
17846173
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.

Irrcher I, Aleyasin H, Seifert EL, Hewitt SJ, Chhabra S, Phillips M, Lutz AK, Rousseaux MW, Bevilacqua L, Jahani-Asl A, Callaghan S, MacLaurin JG, Winklhofer KF, Rizzu P, Rippstein P, Kim RH, Chen CX, Fon EA, Slack RS, Harper ME, McBride HM, Mak TW, Park DS.

Hum Mol Genet. 2010 Oct 1;19(19):3734-46. doi: 10.1093/hmg/ddq288. Epub 2010 Jul 16.

PMID:
20639397
[PubMed - indexed for MEDLINE]
Free Article
20.

Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1.

Haque ME, Mount MP, Safarpour F, Abdel-Messih E, Callaghan S, Mazerolle C, Kitada T, Slack RS, Wallace V, Shen J, Anisman H, Park DS.

J Biol Chem. 2012 Jun 29;287(27):23162-70. doi: 10.1074/jbc.M112.346437. Epub 2012 Apr 17.

PMID:
22511790
[PubMed - indexed for MEDLINE]
Free PMC Article

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