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Results: 1 to 20 of 115

1.

Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1.

Zhao B, Yuan C, Li R, Qu D, Huang M, Ngo JC.

J Biol Chem. 2013 Apr 19;288(16):11155-64. doi: 10.1074/jbc.M113.454611. Epub 2013 Feb 26.

PMID:
23443661
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1.

Kirchhofer D, Peek M, Li W, Stamos J, Eigenbrot C, Kadkhodayan S, Elliott JM, Corpuz RT, Lazarus RA, Moran P.

J Biol Chem. 2003 Sep 19;278(38):36341-9. Epub 2003 Jun 18.

PMID:
12815039
[PubMed - indexed for MEDLINE]
Free Article
3.

Roles of functional and structural domains of hepatocyte growth factor activator inhibitor type 1 in the inhibition of matriptase.

Kojima K, Tsuzuki S, Fushiki T, Inouye K.

J Biol Chem. 2008 Feb 1;283(5):2478-87. Epub 2007 Nov 29.

PMID:
18048349
[PubMed - indexed for MEDLINE]
Free Article
4.

Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.

Shia S, Stamos J, Kirchhofer D, Fan B, Wu J, Corpuz RT, Santell L, Lazarus RA, Eigenbrot C.

J Mol Biol. 2005 Mar 11;346(5):1335-49. Epub 2005 Jan 28.

PMID:
15713485
[PubMed - indexed for MEDLINE]
5.

TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor.

Hashimoto T, Kato M, Shimomura T, Kitamura N.

FEBS J. 2010 Dec;277(23):4888-900. doi: 10.1111/j.1742-4658.2010.07894.x. Epub 2010 Oct 26.

PMID:
20977675
[PubMed - indexed for MEDLINE]
6.

Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase.

Larsen BR, Steffensen SD, Nielsen NV, Friis S, Godiksen S, Bornholdt J, Soendergaard C, Nonboe AW, Andersen MN, Poulsen SS, Szabo R, Bugge TH, Lin CY, Skovbjerg H, Jensen JK, Vogel LK.

Exp Cell Res. 2013 Apr 1;319(6):918-29. doi: 10.1016/j.yexcr.2013.01.008. Epub 2013 Jan 16.

PMID:
23333561
[PubMed - indexed for MEDLINE]
7.

Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity.

Szabo R, Hobson JP, List K, Molinolo A, Lin CY, Bugge TH.

J Biol Chem. 2008 Oct 24;283(43):29495-504. doi: 10.1074/jbc.M801970200. Epub 2008 Aug 19.

PMID:
18713750
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor-1 (HAI-1).

Eigenbrot C, Ganesan R, Kirchhofer D.

FEBS J. 2010 May;277(10):2215-22. doi: 10.1111/j.1742-4658.2010.07638.x. Epub 2010 Apr 9. Review.

PMID:
20402765
[PubMed - indexed for MEDLINE]
9.

Cleavage of hepatocyte growth factor activator inhibitor-1 by membrane-type MMP-1 activates matriptase.

Domoto T, Takino T, Guo L, Sato H.

Cancer Sci. 2012 Mar;103(3):448-54. doi: 10.1111/j.1349-7006.2011.02162.x. Epub 2011 Dec 28.

PMID:
22118498
[PubMed - indexed for MEDLINE]
10.

Functional characterization of Kunitz domains in hepatocyte growth factor activator inhibitor type 1.

Denda K, Shimomura T, Kawaguchi T, Miyazawa K, Kitamura N.

J Biol Chem. 2002 Apr 19;277(16):14053-9. Epub 2002 Jan 22.

PMID:
11805118
[PubMed - indexed for MEDLINE]
Free Article
11.

Purification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1.

Tseng IC, Chou FP, Su SF, Oberst M, Madayiputhiya N, Lee MS, Wang JK, Sloane DE, Johnson M, Lin CY.

Am J Physiol Cell Physiol. 2008 Aug;295(2):C423-31. doi: 10.1152/ajpcell.00164.2008. Epub 2008 Jun 11.

PMID:
18550704
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasin.

Fan B, Wu TD, Li W, Kirchhofer D.

J Biol Chem. 2005 Oct 14;280(41):34513-20. Epub 2005 Aug 15.

PMID:
16103126
[PubMed - indexed for MEDLINE]
Free Article
13.

Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1.

Xu H, Xu Z, Tseng IC, Chou FP, Chen YW, Wang JK, Johnson MD, Kataoka H, Lin CY.

Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C453-62. doi: 10.1152/ajpcell.00344.2011. Epub 2011 Oct 26.

PMID:
22031598
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells.

Lee MS, Kiyomiya K, Benaud C, Dickson RB, Lin CY.

Am J Physiol Cell Physiol. 2005 Apr;288(4):C932-41. Epub 2004 Dec 8.

PMID:
15590895
[PubMed - indexed for MEDLINE]
Free Article
15.

Identification of the matriptase second CUB domain as the secondary site for interaction with hepatocyte growth factor activator inhibitor type-1.

Inouye K, Tsuzuki S, Yasumoto M, Kojima K, Mochida S, Fushiki T.

J Biol Chem. 2010 Oct 22;285(43):33394-403. doi: 10.1074/jbc.M110.115816. Epub 2010 Aug 3.

PMID:
20682770
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.

Wang JK, Lee MS, Tseng IC, Chou FP, Chen YW, Fulton A, Lee HS, Chen CJ, Johnson MD, Lin CY.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C459-70. doi: 10.1152/ajpcell.00201.2009. Epub 2009 Jun 17.

PMID:
19535514
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model.

Ye J, Kawaguchi M, Haruyama Y, Kanemaru A, Fukushima T, Yamamoto K, Lin CY, Kataoka H.

Cancer Sci. 2014 Jan;105(1):44-51. doi: 10.1111/cas.12306. Epub 2013 Nov 25.

PMID:
24147538
[PubMed - indexed for MEDLINE]
18.

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1.

Yuan C, Chen L, Meehan EJ, Daly N, Craik DJ, Huang M, Ngo JC.

BMC Struct Biol. 2011 Jun 22;11:30. doi: 10.1186/1472-6807-11-30.

PMID:
21693064
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo.

Oberst M, Anders J, Xie B, Singh B, Ossandon M, Johnson M, Dickson RB, Lin CY.

Am J Pathol. 2001 Apr;158(4):1301-11.

PMID:
11290548
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Matriptase inhibition by hepatocyte growth factor activator inhibitor-1 is essential for placental development.

Szabo R, Molinolo A, List K, Bugge TH.

Oncogene. 2007 Mar 8;26(11):1546-56. Epub 2006 Sep 18.

PMID:
16983341
[PubMed - indexed for MEDLINE]

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