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Results: 1 to 20 of 118

1.

Kynurenic acid, by targeting α7 nicotinic acetylcholine receptors, modulates extracellular GABA levels in the rat striatum in vivo.

Beggiato S, Antonelli T, Tomasini MC, Tanganelli S, Fuxe K, Schwarcz R, Ferraro L.

Eur J Neurosci. 2013 May;37(9):1470-7. doi: 10.1111/ejn.12160. Epub 2013 Feb 26.

PMID:
23442092
[PubMed - indexed for MEDLINE]
2.

Kynurenic acid leads, dopamine follows: a new case of volume transmission in the brain?

Wu HQ, Rassoulpour A, Schwarcz R.

J Neural Transm. 2007 Jan;114(1):33-41. Epub 2006 Aug 24.

PMID:
16932989
[PubMed - indexed for MEDLINE]
3.

Endogenous kynurenic acid regulates extracellular GABA levels in the rat prefrontal cortex.

Beggiato S, Tanganelli S, Fuxe K, Antonelli T, Schwarcz R, Ferraro L.

Neuropharmacology. 2014 Jul;82:11-8. doi: 10.1016/j.neuropharm.2014.02.019. Epub 2014 Mar 7.

PMID:
24607890
[PubMed - in process]
4.

The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex.

Wu HQ, Pereira EF, Bruno JP, Pellicciari R, Albuquerque EX, Schwarcz R.

J Mol Neurosci. 2010 Jan;40(1-2):204-10. doi: 10.1007/s12031-009-9235-2. Epub 2009 Aug 19.

PMID:
19690987
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory.

Pocivavsek A, Wu HQ, Potter MC, Elmer GI, Pellicciari R, Schwarcz R.

Neuropsychopharmacology. 2011 Oct;36(11):2357-67. doi: 10.1038/npp.2011.127. Epub 2011 Jul 27.

PMID:
21796108
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum.

Amori L, Wu HQ, Marinozzi M, Pellicciari R, Guidetti P, Schwarcz R.

Neuroscience. 2009 Mar 3;159(1):196-203. doi: 10.1016/j.neuroscience.2008.11.055. Epub 2008 Dec 16.

PMID:
19138730
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors.

Lopes C, Pereira EF, Wu HQ, Purushottamachar P, Njar V, Schwarcz R, Albuquerque EX.

J Pharmacol Exp Ther. 2007 Jul;322(1):48-58. Epub 2007 Apr 19.

PMID:
17446300
[PubMed - indexed for MEDLINE]
Free Article
8.

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications.

Hilmas C, Pereira EF, Alkondon M, Rassoulpour A, Schwarcz R, Albuquerque EX.

J Neurosci. 2001 Oct 1;21(19):7463-73.

PMID:
11567036
[PubMed - indexed for MEDLINE]
Free Article
9.

Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum.

Wu HQ, Rassoulpour A, Schwarcz R.

J Neural Transm. 2002 Mar;109(3):239-49.

PMID:
11956948
[PubMed - indexed for MEDLINE]
10.

Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain.

Alkondon M, Pereira EF, Eisenberg HM, Kajii Y, Schwarcz R, Albuquerque EX.

J Pharmacol Exp Ther. 2011 Jun;337(3):572-82. doi: 10.1124/jpet.110.177386. Epub 2011 Jan 26.

PMID:
21270133
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

Alkondon M, Pereira EF, Yu P, Arruda EZ, Almeida LE, Guidetti P, Fawcett WP, Sapko MT, Randall WR, Schwarcz R, Tagle DA, Albuquerque EX.

J Neurosci. 2004 May 12;24(19):4635-48.

PMID:
15140935
[PubMed - indexed for MEDLINE]
Free Article
13.

Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release.

Zmarowski A, Wu HQ, Brooks JM, Potter MC, Pellicciari R, Schwarcz R, Bruno JP.

Eur J Neurosci. 2009 Feb;29(3):529-38. doi: 10.1111/j.1460-9568.2008.06594.x.

PMID:
19187269
[PubMed - indexed for MEDLINE]
14.

Electrophysiological characterisation of the actions of kynurenic acid at ligand-gated ion channels.

Mok MH, Fricker AC, Weil A, Kew JN.

Neuropharmacology. 2009 Sep;57(3):242-9. doi: 10.1016/j.neuropharm.2009.06.003. Epub 2009 Jun 11.

PMID:
19523966
[PubMed - indexed for MEDLINE]
15.

Presynaptic kynurenate-sensitive receptors inhibit glutamate release.

Carpenedo R, Pittaluga A, Cozzi A, Attucci S, Galli A, Raiteri M, Moroni F.

Eur J Neurosci. 2001 Jun;13(11):2141-7.

PMID:
11422455
[PubMed - indexed for MEDLINE]
16.

High tryptophan diet reduces extracellular dopamine release via kynurenic acid production in rat striatum.

Okuno A, Fukuwatari T, Shibata K.

J Neurochem. 2011 Sep;118(5):796-805. doi: 10.1111/j.1471-4159.2011.07369.x. Epub 2011 Jul 21.

PMID:
21711351
[PubMed - indexed for MEDLINE]
17.

Endogenous activation of nAChRs and NMDA receptors contributes to the excitability of CA1 stratum radiatum interneurons in rat hippocampal slices: effects of kynurenic acid.

Alkondon M, Pereira EF, Albuquerque EX.

Biochem Pharmacol. 2011 Oct 15;82(8):842-51. doi: 10.1016/j.bcp.2011.06.004. Epub 2011 Jun 13.

PMID:
21689641
[PubMed - indexed for MEDLINE]
19.

Cortical kynurenic acid bi-directionally modulates prefrontal glutamate levels as assessed by microdialysis and rapid electrochemistry.

Konradsson-Geuken A, Wu HQ, Gash CR, Alexander KS, Campbell A, Sozeri Y, Pellicciari R, Schwarcz R, Bruno JP.

Neuroscience. 2010 Sep 15;169(4):1848-59. doi: 10.1016/j.neuroscience.2010.05.052. Epub 2010 Jun 19.

PMID:
20600676
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

On the antioxidant properties of kynurenic acid: free radical scavenging activity and inhibition of oxidative stress.

Lugo-Huitrón R, Blanco-Ayala T, Ugalde-Muñiz P, Carrillo-Mora P, Pedraza-Chaverrí J, Silva-Adaya D, Maldonado PD, Torres I, Pinzón E, Ortiz-Islas E, López T, García E, Pineda B, Torres-Ramos M, Santamaría A, La Cruz VP.

Neurotoxicol Teratol. 2011 Sep-Oct;33(5):538-47. doi: 10.1016/j.ntt.2011.07.002. Epub 2011 Jul 13.

PMID:
21763768
[PubMed - indexed for MEDLINE]
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