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Results: 1 to 20 of 103

1.

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome.

Kotlarz D, Ziętara N, Uzel G, Weidemann T, Braun CJ, Diestelhorst J, Krawitz PM, Robinson PN, Hecht J, Puchałka J, Gertz EM, Schäffer AA, Lawrence MG, Kardava L, Pfeifer D, Baumann U, Pfister ED, Hanson EP, Schambach A, Jacobs R, Kreipe H, Moir S, Milner JD, Schwille P, Mundlos S, Klein C.

J Exp Med. 2013 Mar 11;210(3):433-43. doi: 10.1084/jem.20111229. Epub 2013 Feb 25.

PMID:
23440042
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

B-cell memory and primary immune deficiencies: interleukin-21 related defects.

Desjardins M, Mazer BD.

Curr Opin Allergy Clin Immunol. 2013 Dec;13(6):639-45. doi: 10.1097/ACI.0000000000000009. Review.

PMID:
24126614
[PubMed - indexed for MEDLINE]
3.

Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.

Ives ML, Ma CS, Palendira U, Chan A, Bustamante J, Boisson-Dupuis S, Arkwright PD, Engelhard D, Averbuch D, Magdorf K, Roesler J, Peake J, Wong M, Adelstein S, Choo S, Smart JM, French MA, Fulcher DA, Cook MC, Picard C, Durandy A, Tsumura M, Kobayashi M, Uzel G, Casanova JL, Tangye SG, Deenick EK.

J Allergy Clin Immunol. 2013 Aug;132(2):400-11.e9. doi: 10.1016/j.jaci.2013.05.029. Epub 2013 Jul 4.

PMID:
23830147
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.

Deenick EK, Avery DT, Chan A, Berglund LJ, Ives ML, Moens L, Stoddard JL, Bustamante J, Boisson-Dupuis S, Tsumura M, Kobayashi M, Arkwright PD, Averbuch D, Engelhard D, Roesler J, Peake J, Wong M, Adelstein S, Choo S, Smart JM, French MA, Fulcher DA, Cook MC, Picard C, Durandy A, Klein C, Holland SM, Uzel G, Casanova JL, Ma CS, Tangye SG.

J Exp Med. 2013 Nov 18;210(12):2739-53. doi: 10.1084/jem.20130323. Epub 2013 Nov 11.

PMID:
24218138
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-alpha.

Yu CR, Lin JX, Fink DW, Akira S, Bloom ET, Yamauchi A.

J Immunol. 1996 Jul 1;157(1):126-37.

PMID:
8683106
[PubMed - indexed for MEDLINE]
6.

IFN-alpha regulates IL-21 and IL-21R expression in human NK and T cells.

Strengell M, Julkunen I, Matikainen S.

J Leukoc Biol. 2004 Aug;76(2):416-22. Epub 2004 Jun 3.

PMID:
15178704
[PubMed - indexed for MEDLINE]
Free Article
7.

Interleukin-21 differentially affects human natural killer cell subsets.

Wendt K, Wilk E, Buyny S, Schmidt RE, Jacobs R.

Immunology. 2007 Dec;122(4):486-95. Epub 2007 Jul 16.

PMID:
17635612
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome.

Renner ED, Rylaarsdam S, Anover-Sombke S, Rack AL, Reichenbach J, Carey JC, Zhu Q, Jansson AF, Barboza J, Schimke LF, Leppert MF, Getz MM, Seger RA, Hill HR, Belohradsky BH, Torgerson TR, Ochs HD.

J Allergy Clin Immunol. 2008 Jul;122(1):181-7. doi: 10.1016/j.jaci.2008.04.037.

PMID:
18602572
[PubMed - indexed for MEDLINE]
9.

The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3.

Habib T, Senadheera S, Weinberg K, Kaushansky K.

Biochemistry. 2002 Jul 9;41(27):8725-31.

PMID:
12093291
[PubMed - indexed for MEDLINE]
10.

Defects along the T(H)17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome.

Al Khatib S, Keles S, Garcia-Lloret M, Karakoc-Aydiner E, Reisli I, Artac H, Camcioglu Y, Cokugras H, Somer A, Kutukculer N, Yilmaz M, Ikinciogullari A, Yegin O, Yüksek M, Genel F, Kucukosmanoglu E, Baki A, Bahceciler NN, Rambhatla A, Nickerson DW, McGhee S, Barlan IB, Chatila T.

J Allergy Clin Immunol. 2009 Aug;124(2):342-8, 348.e1-5. doi: 10.1016/j.jaci.2009.05.004. Epub 2009 Jul 3.

PMID:
19577286
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Signal transducer and activator of transcription 3 (STAT3) and Suppressor of Cytokine Signaling (SOCS3) balance controls cytotoxicity and IL-10 expression in decidual-like natural killer cell line NK-92.

Braunschweig A, Poehlmann TG, Busch S, Schleussner E, Markert UR.

Am J Reprod Immunol. 2011 Oct;66(4):329-35. doi: 10.1111/j.1600-0897.2011.00989.x. Epub 2011 Mar 9.

PMID:
21385272
[PubMed - indexed for MEDLINE]
12.

Regulation of interleukin-21 receptor expression and its signal transduction by WSB-2.

Nara H, Onoda T, Rahman M, Araki A, Juliana FM, Tanaka N, Asao H.

Biochem Biophys Res Commun. 2010 Feb 5;392(2):171-7. doi: 10.1016/j.bbrc.2010.01.004. Epub 2010 Jan 6.

PMID:
20059963
[PubMed - indexed for MEDLINE]
13.

Umbilical cord blood transplantation in severe T-cell immunodeficiency disorders: two-year experience.

Knutsen AP, Wall DA.

J Clin Immunol. 2000 Nov;20(6):466-76.

PMID:
11202237
[PubMed - indexed for MEDLINE]
14.

Expression of functional interleukin-21 receptor on adult T-cell leukaemia cells.

Ueda M, Imada K, Imura A, Koga H, Hishizawa M, Uchiyama T.

Br J Haematol. 2005 Jan;128(2):169-76.

PMID:
15638850
[PubMed - indexed for MEDLINE]
15.

Interleukin-21 up-regulates interleukin-21R expression and interferon gamma production by CD8+ cells in SHIV-infected macaques.

Zhao CC, Gao XQ, Xue J, Cong Z, Zhang WL, Chen T, Wu FX, Xiong J, Ju B, Su A, Wei Q, Qin C.

Exp Biol Med (Maywood). 2013 Apr;238(4):400-9. doi: 10.1177/1535370213477978.

PMID:
23760006
[PubMed - indexed for MEDLINE]
16.

[Primary immunodeficiencies. Clinical features and variant forms].

Fontán Casariego G.

Allergol Immunopathol (Madr). 2001 May-Jun;29(3):101-7. Review. Spanish.

PMID:
11434882
[PubMed - indexed for MEDLINE]
17.

Comèl-Netherton syndrome defined as primary immunodeficiency.

Renner ED, Hartl D, Rylaarsdam S, Young ML, Monaco-Shawver L, Kleiner G, Markert ML, Stiehm ER, Belohradsky BH, Upton MP, Torgerson TR, Orange JS, Ochs HD.

J Allergy Clin Immunol. 2009 Sep;124(3):536-43. doi: 10.1016/j.jaci.2009.06.009. Epub 2009 Aug 14. Erratum in: J Allergy Clin Immunol. 2009 Dec;124(6):1318.

PMID:
19683336
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined immunodeficiency.

Roifman CM, Zhang J, Chitayat D, Sharfe N.

Blood. 2000 Oct 15;96(8):2803-7.

PMID:
11023514
[PubMed - indexed for MEDLINE]
Free Article
19.

Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.

de Jager W, Vastert SJ, Beekman JM, Wulffraat NM, Kuis W, Coffer PJ, Prakken BJ.

Arthritis Rheum. 2009 Sep;60(9):2782-93. doi: 10.1002/art.24750.

PMID:
19714583
[PubMed - indexed for MEDLINE]
Free Article
20.

The molecular basis of IL-21-mediated proliferation.

Zeng R, Spolski R, Casas E, Zhu W, Levy DE, Leonard WJ.

Blood. 2007 May 15;109(10):4135-42. Epub 2007 Jan 18.

PMID:
17234735
[PubMed - indexed for MEDLINE]
Free PMC Article

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