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Results: 1 to 20 of 117

1.

MiR-138 and MiR-135 directly target focal adhesion kinase, inhibit cell invasion, and increase sensitivity to chemotherapy in cancer cells.

Golubovskaya VM, Sumbler B, Ho B, Yemma M, Cance WG.

Anticancer Agents Med Chem. 2014 Jan;14(1):18-28.

PMID:
23438844
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression.

Kong X, Li G, Yuan Y, He Y, Wu X, Zhang W, Wu Z, Chen T, Wu W, Lobie PE, Zhu T.

PLoS One. 2012;7(8):e41523. doi: 10.1371/journal.pone.0041523. Epub 2012 Aug 2.

PMID:
22876288
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

MicroRNA-7 regulates glioblastoma cell invasion via targeting focal adhesion kinase expression.

Wu DG, Wang YY, Fan LG, Luo H, Han B, Sun LH, Wang XF, Zhang JX, Cao L, Wang XR, You YP, Liu N.

Chin Med J (Engl). 2011 Sep;124(17):2616-21.

PMID:
22040413
[PubMed - indexed for MEDLINE]
Free Article
4.

Focal adhesion kinase regulates expression of thioredoxin-interacting protein (TXNIP) in cancer cells.

Ho B, Huang G, Golubovskaya VM.

Anticancer Agents Med Chem. 2014 Jan;14(1):3-8.

PMID:
23387972
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

miR-150 promotes the proliferation and migration of lung cancer cells by targeting SRC kinase signalling inhibitor 1.

Cao M, Hou D, Liang H, Gong F, Wang Y, Yan X, Jiang X, Wang C, Zhang J, Zen K, Zhang CY, Chen X.

Eur J Cancer. 2014 Mar;50(5):1013-24. doi: 10.1016/j.ejca.2013.12.024. Epub 2014 Jan 20.

PMID:
24456795
[PubMed - indexed for MEDLINE]
6.

MiR-181a enhances drug sensitivity in mitoxantone-resistant breast cancer cells by targeting breast cancer resistance protein (BCRP/ABCG2).

Jiao X, Zhao L, Ma M, Bai X, He M, Yan Y, Wang Y, Chen Q, Zhao X, Zhou M, Cui Z, Zheng Z, Wang E, Wei M.

Breast Cancer Res Treat. 2013 Jun;139(3):717-30. doi: 10.1007/s10549-013-2607-x. Epub 2013 Jun 19.

PMID:
23780685
[PubMed - indexed for MEDLINE]
7.

Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells.

Buurman R, Gürlevik E, Schäffer V, Eilers M, Sandbothe M, Kreipe H, Wilkens L, Schlegelberger B, Kühnel F, Skawran B.

Gastroenterology. 2012 Sep;143(3):811-20.e1-15. doi: 10.1053/j.gastro.2012.05.033. Epub 2012 May 26.

PMID:
22641068
[PubMed - indexed for MEDLINE]
8.

Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer.

Chiyomaru T, Yamamura S, Fukuhara S, Hidaka H, Majid S, Saini S, Arora S, Deng G, Shahryari V, Chang I, Tanaka Y, Tabatabai ZL, Enokida H, Seki N, Nakagawa M, Dahiya R.

PLoS One. 2013;8(3):e58929. doi: 10.1371/journal.pone.0058929. Epub 2013 Mar 12.

PMID:
23554959
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MicroRNA-661, a c/EBPalpha target, inhibits metastatic tumor antigen 1 and regulates its functions.

Reddy SD, Pakala SB, Ohshiro K, Rayala SK, Kumar R.

Cancer Res. 2009 Jul 15;69(14):5639-42. doi: 10.1158/0008-5472.CAN-09-0898. Epub 2009 Jul 7.

PMID:
19584269
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).

Zhu S, Si ML, Wu H, Mo YY.

J Biol Chem. 2007 May 11;282(19):14328-36. Epub 2007 Mar 15.

PMID:
17363372
[PubMed - indexed for MEDLINE]
Free Article
11.

FAK and HAS inhibition synergistically decrease colon cancer cell viability and affect expression of critical genes.

Heffler M, Golubovskaya VM, Conroy J, Liu S, Wang D, Cance WG, Dunn KB.

Anticancer Agents Med Chem. 2013 May;13(4):584-94.

PMID:
22934709
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Galangin inhibits tumor growth and metastasis of B16F10 melanoma.

Zhang W, Tang B, Huang Q, Hua Z.

J Cell Biochem. 2013 Jan;114(1):152-61. doi: 10.1002/jcb.24312.

PMID:
22887049
[PubMed - indexed for MEDLINE]
13.

A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

Hochwald SN, Nyberg C, Zheng M, Zheng D, Wood C, Massoll NA, Magis A, Ostrov D, Cance WG, Golubovskaya VM.

Cell Cycle. 2009 Aug;8(15):2435-43. Epub 2009 Aug 1.

PMID:
19571674
[PubMed - indexed for MEDLINE]
Free Article
14.

Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.

Heffler M, Golubovskaya VM, Dunn KM, Cance W.

Cancer Biol Ther. 2013 Aug;14(8):761-72. doi: 10.4161/cbt.25185. Epub 2013 Jun 3.

PMID:
23792569
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.

Liang L, Li X, Zhang X, Lv Z, He G, Zhao W, Ren X, Li Y, Bian X, Liao W, Liu W, Yang G, Ding Y.

Gastroenterology. 2013 Mar;144(3):624-635.e4. doi: 10.1053/j.gastro.2012.11.033. Epub 2012 Nov 27.

PMID:
23201162
[PubMed - indexed for MEDLINE]
16.

A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.

Golubovskaya VM, Palma NL, Zheng M, Ho B, Magis A, Ostrov D, Cance WG.

Anticancer Agents Med Chem. 2013 May;13(4):532-45.

PMID:
22292771
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor.

Lee HK, Bier A, Cazacu S, Finniss S, Xiang C, Twito H, Poisson LM, Mikkelsen T, Slavin S, Jacoby E, Yalon M, Toren A, Rempel SA, Brodie C.

PLoS One. 2013;8(2):e54652. doi: 10.1371/journal.pone.0054652. Epub 2013 Feb 4.

PMID:
23390502
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

miRNA-939 regulates human inducible nitric oxide synthase posttranscriptional gene expression in human hepatocytes.

Guo Z, Shao L, Zheng L, Du Q, Li P, John B, Geller DA.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5826-31. doi: 10.1073/pnas.1118118109. Epub 2012 Mar 26.

PMID:
22451906
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

miRNA-141, downregulated in pancreatic cancer, inhibits cell proliferation and invasion by directly targeting MAP4K4.

Zhao G, Wang B, Liu Y, Zhang JG, Deng SC, Qin Q, Tian K, Li X, Zhu S, Niu Y, Gong Q, Wang CY.

Mol Cancer Ther. 2013 Nov;12(11):2569-80. doi: 10.1158/1535-7163.MCT-13-0296. Epub 2013 Sep 6.

PMID:
24013097
[PubMed - indexed for MEDLINE]
20.

[miR-216b suppresses cell proliferation and invasion by targeting PKCα in nasopharyngeal carcinoma cells].

Deng M, Liu JF, Gu YX, Zheng GP, He ZM.

Zhonghua Zhong Liu Za Zhi. 2013 Sep;35(9):645-50. Chinese.

PMID:
24332049
[PubMed - indexed for MEDLINE]

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