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Results: 1 to 20 of 169

1.

SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state.

Lodato MA, Ng CW, Wamstad JA, Cheng AW, Thai KK, Fraenkel E, Jaenisch R, Boyer LA.

PLoS Genet. 2013;9(2):e1003288. doi: 10.1371/journal.pgen.1003288. Epub 2013 Feb 21.

PMID:
23437007
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates.

Iwafuchi-Doi M, Yoshida Y, Onichtchouk D, Leichsenring M, Driever W, Takemoto T, Uchikawa M, Kamachi Y, Kondoh H.

Dev Biol. 2011 Apr 15;352(2):354-66. doi: 10.1016/j.ydbio.2010.12.027. Epub 2010 Dec 23.

PMID:
21185279
[PubMed - indexed for MEDLINE]
Free Article
3.

Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells.

Chew JL, Loh YH, Zhang W, Chen X, Tam WL, Yeap LS, Li P, Ang YS, Lim B, Robson P, Ng HH.

Mol Cell Biol. 2005 Jul;25(14):6031-46.

PMID:
15988017
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

Catena R, Tiveron C, Ronchi A, Porta S, Ferri A, Tatangelo L, Cavallaro M, Favaro R, Ottolenghi S, Reinbold R, Schöler H, Nicolis SK.

J Biol Chem. 2004 Oct 1;279(40):41846-57. Epub 2004 Jul 15.

PMID:
15262984
[PubMed - indexed for MEDLINE]
Free Article
5.

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, Takahashi K, Okochi H, Okuda A, Matoba R, Sharov AA, Ko MS, Niwa H.

Nat Cell Biol. 2007 Jun;9(6):625-35. Epub 2007 May 21.

PMID:
17515932
[PubMed - indexed for MEDLINE]
6.

Identification of DPPA4 and other genes as putative Sox2:Oct-3/4 target genes using a combination of in silico analysis and transcription-based assays.

Chakravarthy H, Boer B, Desler M, Mallanna SK, McKeithan TW, Rizzino A.

J Cell Physiol. 2008 Sep;216(3):651-62. doi: 10.1002/jcp.21440.

PMID:
18366076
[PubMed - indexed for MEDLINE]
7.

Enhancer identification in mouse embryonic stem cells using integrative modeling of chromatin and genomic features.

Chen CY, Morris Q, Mitchell JA.

BMC Genomics. 2012 Apr 26;13:152. doi: 10.1186/1471-2164-13-152.

PMID:
22537144
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Oct4 and Sox2 directly regulate expression of another pluripotency transcription factor, Zfp206, in embryonic stem cells.

Wang ZX, Teh CH, Kueh JL, Lufkin T, Robson P, Stanton LW.

J Biol Chem. 2007 Apr 27;282(17):12822-30. Epub 2007 Mar 7.

PMID:
17344211
[PubMed - indexed for MEDLINE]
Free Article
9.

A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells.

Jung M, Peterson H, Chavez L, Kahlem P, Lehrach H, Vilo J, Adjaye J.

PLoS One. 2010 May 21;5(5):e10709. doi: 10.1371/journal.pone.0010709.

PMID:
20505756
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2).

Sussman RT, Stanek TJ, Esteso P, Gearhart JD, Knudsen KE, McMahon SB.

J Biol Chem. 2013 Aug 16;288(33):24234-46. doi: 10.1074/jbc.M113.469783. Epub 2013 Jun 12.

PMID:
23760504
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development.

Jin Z, Liu L, Bian W, Chen Y, Xu G, Cheng L, Jing N.

J Biol Chem. 2009 Mar 20;284(12):8160-73. doi: 10.1074/jbc.M805632200. Epub 2009 Jan 15.

PMID:
19147497
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells.

Yang J, Chai L, Fowles TC, Alipio Z, Xu D, Fink LM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19756-61. doi: 10.1073/pnas.0809321105. Epub 2008 Dec 5.

PMID:
19060217
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells.

Liu X, Huang J, Chen T, Wang Y, Xin S, Li J, Pei G, Kang J.

Cell Res. 2008 Dec;18(12):1177-89. doi: 10.1038/cr.2008.309.

PMID:
19030024
[PubMed - indexed for MEDLINE]
14.

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

Aksoy I, Jauch R, Chen J, Dyla M, Divakar U, Bogu GK, Teo R, Leng Ng CK, Herath W, Lili S, Hutchins AP, Robson P, Kolatkar PR, Stanton LW.

EMBO J. 2013 Apr 3;32(7):938-53. doi: 10.1038/emboj.2013.31. Epub 2013 Mar 8.

PMID:
23474895
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells.

Card DA, Hebbar PB, Li L, Trotter KW, Komatsu Y, Mishina Y, Archer TK.

Mol Cell Biol. 2008 Oct;28(20):6426-38. doi: 10.1128/MCB.00359-08. Epub 2008 Aug 18.

PMID:
18710938
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Stable expression of FoxA1 promotes pluripotent P19 embryonal carcinoma cells to be neural stem-like cells.

Dong D, Meng L, Yu Q, Tan G, Ding M, Tan Y.

Gene Expr. 2012;15(4):153-62.

PMID:
22783724
[PubMed - indexed for MEDLINE]
17.

Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors.

Inoue F, Kurokawa D, Takahashi M, Aizawa S.

Mol Cell Biol. 2012 Jul;32(13):2618-27. doi: 10.1128/MCB.00083-12. Epub 2012 May 7.

PMID:
22566684
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Stemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse embryonic stem cells.

Tanimura N, Saito M, Ebisuya M, Nishida E, Ishikawa F.

J Biol Chem. 2013 Feb 15;288(7):5027-38. doi: 10.1074/jbc.M112.411173. Epub 2012 Dec 26.

PMID:
23269686
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

Chia NY, Chan YS, Feng B, Lu X, Orlov YL, Moreau D, Kumar P, Yang L, Jiang J, Lau MS, Huss M, Soh BS, Kraus P, Li P, Lufkin T, Lim B, Clarke ND, Bard F, Ng HH.

Nature. 2010 Nov 11;468(7321):316-20. doi: 10.1038/nature09531. Epub 2010 Oct 17.

PMID:
20953172
[PubMed - indexed for MEDLINE]
20.

A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells.

Fong YW, Inouye C, Yamaguchi T, Cattoglio C, Grubisic I, Tjian R.

Cell. 2011 Sep 30;147(1):120-31. doi: 10.1016/j.cell.2011.08.038.

PMID:
21962512
[PubMed - indexed for MEDLINE]
Free PMC Article

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