Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 98

1.

A semimechanistic model of the time-course of release of PTH into plasma following administration of the calcilytic JTT-305/MK-5442 in humans.

Cabal A, Mehta K, Ross DS, Shrestha RP, Comisar W, Denker A, Pai SM, Ishikawa T.

J Bone Miner Res. 2013 Aug;28(8):1830-6. doi: 10.1002/jbmr.1900.

PMID:
23436611
[PubMed - indexed for MEDLINE]
2.

Pharmacodynamic responses to combined treatment regimens with the calcium sensing receptor antagonist JTT-305/MK-5442 and alendronate in osteopenic ovariectomized rats.

Fisher JE, Scott K, Wei N, Zhao JZ, Cusick T, Tijerina M, Karanam B, Duong L, Glantschnig H.

Bone. 2012 Jun;50(6):1332-42. doi: 10.1016/j.bone.2012.03.004. Epub 2012 Mar 14.

PMID:
22445539
[PubMed - indexed for MEDLINE]
3.

JTT-305, an orally active calcium-sensing receptor antagonist, stimulates transient parathyroid hormone release and bone formation in ovariectomized rats.

Kimura S, Nakagawa T, Matsuo Y, Ishida Y, Okamoto Y, Hayashi M.

Eur J Pharmacol. 2011 Oct 1;668(1-2):331-6. doi: 10.1016/j.ejphar.2011.07.015. Epub 2011 Jul 28.

PMID:
21810422
[PubMed - indexed for MEDLINE]
4.

[Antagonist for calcium-sensing receptor. JTT-305/MK-5442].

Fukumoto S.

Clin Calcium. 2011 Jan;21(1):89-93. doi: CliCa11018993. Review. Japanese.

PMID:
21187599
[PubMed - indexed for MEDLINE]
5.

Mixed-effects modeling of the pharmacodynamic response to the calcimimetic agent R-568.

Lalonde RL, Gaudreault J, Karhu DA, Marriott TB.

Clin Pharmacol Ther. 1999 Jan;65(1):40-9.

PMID:
9951429
[PubMed - indexed for MEDLINE]
6.

ATF936, a novel oral calcilytic, increases bone mineral density in rats and transiently releases parathyroid hormone in humans.

John MR, Widler L, Gamse R, Buhl T, Seuwen K, Breitenstein W, Bruin GJ, Belleli R, Klickstein LB, Kneissel M.

Bone. 2011 Aug;49(2):233-41. doi: 10.1016/j.bone.2011.04.007. Epub 2011 Apr 14.

PMID:
21514409
[PubMed - indexed for MEDLINE]
7.

Pharmacodynamic model of parathyroid hormone modulation by a negative allosteric modulator of the calcium-sensing receptor.

Abraham AK, Maurer TS, Kalgutkar AS, Gao X, Li M, Healy DR, Petersen DN, Griffith DA, Mager DE.

AAPS J. 2011 Jun;13(2):265-73. doi: 10.1208/s12248-011-9266-9. Epub 2011 Mar 25.

PMID:
21437757
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Effects of growth hormone administration on bone mineral metabolism, PTH sensitivity and PTH secretory rhythm in postmenopausal women with established osteoporosis.

Joseph F, Ahmad AM, Ul-Haq M, Durham BH, Whittingham P, Fraser WD, Vora JP.

J Bone Miner Res. 2008 May;23(5):721-9.

PMID:
18052753
[PubMed - indexed for MEDLINE]
9.

Parathyroid hormone temporal effects on bone formation and resorption.

Kroll MH.

Bull Math Biol. 2000 Jan;62(1):163-88.

PMID:
10824426
[PubMed - indexed for MEDLINE]
10.

AXT914 a novel, orally-active parathyroid hormone-releasing drug in two early studies of healthy volunteers and postmenopausal women.

John MR, Harfst E, Loeffler J, Belleli R, Mason J, Bruin GJ, Seuwen K, Klickstein LB, Mindeholm L, Widler L, Kneissel M.

Bone. 2014 Jul;64:204-10. doi: 10.1016/j.bone.2014.04.015. Epub 2014 Apr 24.

PMID:
24769332
[PubMed - in process]
11.

Characterization of the effect of chronic administration of a calcium-sensing receptor antagonist, ronacaleret, on renal calcium excretion and serum calcium in postmenopausal women.

Caltabiano S, Dollery CT, Hossain M, Kurtinecz MT, Desjardins JP, Favus MJ, Kumar R, Fitzpatrick LA.

Bone. 2013 Sep;56(1):154-62. doi: 10.1016/j.bone.2013.05.021. Epub 2013 Jun 10.

PMID:
23756230
[PubMed - indexed for MEDLINE]
13.

Effect of high doses of oral risedronate (20 mg/day) on serum parathyroid hormone levels and urinary collagen cross-link excretion in postmenopausal women with spinal osteoporosis.

Zegels B, Eastell R, Russell RG, Ethgen D, Roumagnac I, Collette J, Reginster JY.

Bone. 2001 Jan;28(1):108-12.

PMID:
11165950
[PubMed - indexed for MEDLINE]
14.

The search for calcium receptor antagonists (calcilytics).

Nemeth EF.

J Mol Endocrinol. 2002 Aug;29(1):15-21. Review.

PMID:
12200226
[PubMed - indexed for MEDLINE]
Free Article
15.

Mechanism-based pharmacokinetic/pharmacodynamic model of parathyroid hormone-calcium homeostasis in rats and humans.

Abraham AK, Mager DE, Gao X, Li M, Healy DR, Maurer TS.

J Pharmacol Exp Ther. 2009 Jul;330(1):169-78. doi: 10.1124/jpet.109.152033. Epub 2009 Apr 22.

PMID:
19386792
[PubMed - indexed for MEDLINE]
Free Article
16.

An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation.

Kumar S, Matheny CJ, Hoffman SJ, Marquis RW, Schultz M, Liang X, Vasko JA, Stroup GB, Vaden VR, Haley H, Fox J, DelMar EG, Nemeth EF, Lago AM, Callahan JF, Bhatnagar P, Huffman WF, Gowen M, Yi B, Danoff TM, Fitzpatrick LA.

Bone. 2010 Feb;46(2):534-42. doi: 10.1016/j.bone.2009.09.028. Epub 2009 Sep 26.

PMID:
19786130
[PubMed - indexed for MEDLINE]
17.

A novel synthetic triazolotriazepine derivative JTT-606 inhibits bone resorption by down-regulation of action and production of bone resorptive factors.

Chikazu D, Shindo M, Iwasaka T, Katagiri M, Manabe N, Takato T, Nakamura K, Kawaguchi H.

J Bone Miner Res. 2000 Apr;15(4):674-82.

PMID:
10780859
[PubMed - indexed for MEDLINE]
18.

Influence of daily regimen calcium and vitamin D supplementation on parathyroid hormone secretion.

Reginster JY, Zegels B, Lejeune E, Micheletti MC, Kvsaz A, Seidel L, Sarlet N.

Calcif Tissue Int. 2002 Feb;70(2):78-82. Epub 2002 Jan 28.

PMID:
11870412
[PubMed - indexed for MEDLINE]
19.

In vivo studies of parathyroid gland function in secondary hyperparathyroidism.

Salusky IB, Goodman WG.

Adv Nephrol Necker Hosp. 1996;25:289-302. Review.

PMID:
8717632
[PubMed - indexed for MEDLINE]
20.

Estrogen replacement decreases the set point of parathyroid hormone stimulation by calcium in normal postmenopausal women.

Boucher A, D'Amour P, Hamel L, Fugère P, Gascon-Barré M, Lepage R, Ste-Marie LG.

J Clin Endocrinol Metab. 1989 Apr;68(4):831-6.

PMID:
2921312
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk