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Items: 1 to 20 of 191


In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae.

Ko FC, Dragomir C, Plumb DA, Goldring SR, Wright TM, Goldring MB, van der Meulen MC.

Arthritis Rheum. 2013 Jun;65(6):1569-78. doi: 10.1002/art.37906.


Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis.

Mohan G, Perilli E, Kuliwaba JS, Humphries JM, Parkinson IH, Fazzalari NL.

Arthritis Res Ther. 2011;13(6):R210. doi: 10.1186/ar3543. Epub 2011 Dec 21.


Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis.

Sniekers YH, Weinans H, van Osch GJ, van Leeuwen JP.

Arthritis Res Ther. 2010;12(5):R182. doi: 10.1186/ar3148. Epub 2010 Oct 5.


Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: an in vivo microfocal computed tomography study.

Botter SM, van Osch GJ, Clockaerts S, Waarsing JH, Weinans H, van Leeuwen JP.

Arthritis Rheum. 2011 Sep;63(9):2690-9. doi: 10.1002/art.30307.


ADAMTS5-/- mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes.

Botter SM, Glasson SS, Hopkins B, Clockaerts S, Weinans H, van Leeuwen JP, van Osch GJ.

Osteoarthritis Cartilage. 2009 May;17(5):636-45. doi: 10.1016/j.joca.2008.09.018. Epub 2008 Oct 17.


Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis.

Botter SM, van Osch GJ, Waarsing JH, van der Linden JC, Verhaar JA, Pols HA, van Leeuwen JP, Weinans H.

Osteoarthritis Cartilage. 2008 Apr;16(4):506-14. Epub 2007 Sep 27.


Chronic in vivo load alteration induces degenerative changes in the rat tibiofemoral joint.

Roemhildt ML, Beynnon BD, Gauthier AE, Gardner-Morse M, Ertem F, Badger GJ.

Osteoarthritis Cartilage. 2013 Feb;21(2):346-57. doi: 10.1016/j.joca.2012.10.014. Epub 2012 Nov 1.


Quantification of subchondral bone changes in a murine osteoarthritis model using micro-CT.

Botter SM, van Osch GJ, Waarsing JH, Day JS, Verhaar JA, Pols HA, van Leeuwen JP, Weinans H.

Biorheology. 2006;43(3-4):379-88.


Pre-emptive, early, and delayed alendronate treatment in a rat model of knee osteoarthritis: effect on subchondral trabecular bone microarchitecture and cartilage degradation of the tibia, bone/cartilage turnover, and joint discomfort.

Mohan G, Perilli E, Parkinson IH, Humphries JM, Fazzalari NL, Kuliwaba JS.

Osteoarthritis Cartilage. 2013 Oct;21(10):1595-604. doi: 10.1016/j.joca.2013.06.020. Epub 2013 Jul 1.


Spatial and temporal changes of subchondral bone proceed to microscopic articular cartilage degeneration in guinea pigs with spontaneous osteoarthritis.

Wang T, Wen CY, Yan CH, Lu WW, Chiu KY.

Osteoarthritis Cartilage. 2013 Apr;21(4):574-81. doi: 10.1016/j.joca.2013.01.002. Epub 2013 Jan 9.


Development of osteoarthritic features in estrogen receptor knockout mice.

Sniekers YH, van Osch GJ, Ederveen AG, Inzunza J, Gustafsson JA, van Leeuwen JP, Weinans H.

Osteoarthritis Cartilage. 2009 Oct;17(10):1356-61. doi: 10.1016/j.joca.2009.04.008. Epub 2009 Apr 17.


Osteoarthritis in cynomolgus macaques. III: Effects of age, gender, and subchondral bone thickness on the severity of disease.

Carlson CS, Loeser RF, Purser CB, Gardin JF, Jerome CP.

J Bone Miner Res. 1996 Sep;11(9):1209-17.


Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis.

Christiansen BA, Anderson MJ, Lee CA, Williams JC, Yik JH, Haudenschild DR.

Osteoarthritis Cartilage. 2012 Jul;20(7):773-82. doi: 10.1016/j.joca.2012.04.014. Epub 2012 Apr 21.


[Comparative histomorphometry of subchondral bone density and articular cartilage thickness in the tibial head in early human arthritis].

Böhringer ME, Beyer WF, Weseloh G.

Z Orthop Ihre Grenzgeb. 1995 Jul-Aug;133(4):291-302. Review. German.


Osteoarthitis of leptin-deficient ob/ob mice in response to biomechanical loading in micro-CT.

Heep H, Hilken G, Hofmeister S, Wedemeyer C.

Int J Biol Sci. 2009;5(3):265-75. Epub 2009 Mar 18.


The effects of bone remodeling inhibition by alendronate on three-dimensional microarchitecture of subchondral bone tissues in guinea pig primary osteoarthrosis.

Ding M, Danielsen CC, Hvid I.

Calcif Tissue Int. 2008 Jan;82(1):77-86. doi: 10.1007/s00223-007-9093-2. Epub 2008 Jan 4.


In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.

Valverde-Franco G, Pelletier JP, Fahmi H, Hum D, Matsuo K, Lussier B, Kapoor M, Martel-Pelletier J.

Arthritis Rheum. 2012 Nov;64(11):3614-25. doi: 10.1002/art.34638.


The effects of orally administered diacerein on cartilage and subchondral bone in an ovine model of osteoarthritis.

Hwa SY, Burkhardt D, Little C, Ghosh P.

J Rheumatol. 2001 Apr;28(4):825-34.

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