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Items: 1 to 20 of 128

1.

The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer.

Anisimov VN, Bartke A.

Crit Rev Oncol Hematol. 2013 Sep;87(3):201-23. doi: 10.1016/j.critrevonc.2013.01.005. Epub 2013 Feb 21. Review.

2.

Metformin for aging and cancer prevention.

Anisimov VN.

Aging (Albany NY). 2010 Nov;2(11):760-74. Review.

3.

Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.

Anisimov VN, Berstein LM, Popovich IG, Zabezhinski MA, Egormin PA, Tyndyk ML, Anikin IV, Semenchenko AV, Yashin AI.

Ann N Y Acad Sci. 2005 Dec;1057:220-34.

PMID:
16399897
4.

[Role of the growth hormone-insulin-like growth factor-1-insulin system signaling in aging and longevity: evolutional aspect].

Anisimov VN.

Ross Fiziol Zh Im I M Sechenova. 2008 Sep;94(9):1092-109. Review. Russian.

PMID:
18953996
5.
6.

Metformin: do we finally have an anti-aging drug?

Anisimov VN.

Cell Cycle. 2013 Nov 15;12(22):3483-9. doi: 10.4161/cc.26928. Epub 2013 Oct 24. Review.

7.

Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for aging and cancer prevention: do we really have an antiaging drug?

Anisimov VN.

Interdiscip Top Gerontol. 2015;40:177-88. doi: 10.1159/000364982. Epub 2014 Oct 13. Review.

PMID:
25341521
8.

Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.

Berryman DE, Christiansen JS, Johannsson G, Thorner MO, Kopchick JJ.

Growth Horm IGF Res. 2008 Dec;18(6):455-71. doi: 10.1016/j.ghir.2008.05.005. Epub 2008 Aug 16. Review.

9.

Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.

Anisimov VN, Berstein LM, Egormin PA, Piskunova TS, Popovich IG, Zabezhinski MA, Kovalenko IG, Poroshina TE, Semenchenko AV, Provinciali M, Re F, Franceschi C.

Exp Gerontol. 2005 Aug-Sep;40(8-9):685-93.

PMID:
16125352
10.

The insulin/IGF-1 signaling in mammals and its relevance to human longevity.

Rincon M, Rudin E, Barzilai N.

Exp Gerontol. 2005 Nov;40(11):873-7. Epub 2005 Sep 15. Review.

PMID:
16168602
11.

Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies.

Sonntag WE, Csiszar A, deCabo R, Ferrucci L, Ungvari Z.

J Gerontol A Biol Sci Med Sci. 2012 Jun;67(6):587-98. doi: 10.1093/gerona/gls115. Epub 2012 Apr 20. Review.

12.

Igf-I signaling and effects on longevity.

Holzenberger M.

Nestle Nutr Workshop Ser Pediatr Program. 2011;68:237-45; discussion 246-9. doi: 10.1159/000325914. Epub 2011 Oct 3. Review.

PMID:
22044904
13.

Insulin-like growth factor 1 (IGF-1) and aging: controversies and new insights.

Bartke A, Chandrashekar V, Dominici F, Turyn D, Kinney B, Steger R, Kopchick JJ.

Biogerontology. 2003;4(1):1-8. Review.

PMID:
12652183
14.

Genetic variation in insulin/IGF-1 signaling pathways and longevity.

Ziv E, Hu D.

Ageing Res Rev. 2011 Apr;10(2):201-4. doi: 10.1016/j.arr.2010.09.002. Epub 2010 Sep 22. Review.

PMID:
20868776
15.

The GH/IGF-I axis and longevity.

Holzenberger M.

Eur J Endocrinol. 2004 Aug;151 Suppl 1:S23-7.

16.

Caloric restriction and growth hormone receptor knockout: effects on expression of genes involved in insulin action in the heart.

Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Jimenez-Ortega V, Panici JA, Bonkowski MS, Kopchick JJ, Wang Z, Bartke A.

Exp Gerontol. 2006 Apr;41(4):417-29. Epub 2006 Mar 9.

17.

Role of the IGF/insulin system in longevity.

Mari D.

Minerva Endocrinol. 2011 Sep;36(3):181-5.

PMID:
22019749
18.

Single-gene mutations and healthy ageing in mammals.

Bartke A.

Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):28-34. doi: 10.1098/rstb.2010.0281. Review.

19.

Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm.

Hsieh CC, DeFord JH, Flurkey K, Harrison DE, Papaconstantinou J.

Mech Ageing Dev. 2002 May;123(9):1229-44.

PMID:
12020945
20.

Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction.

Shimokawa I, Higami Y, Tsuchiya T, Otani H, Komatsu T, Chiba T, Yamaza H.

FASEB J. 2003 Jun;17(9):1108-9. Epub 2003 Apr 8.

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