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Results: 1 to 20 of 97

1.

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.

Dreier B, Honegger A, Hess C, Nagy-Davidescu G, Mittl PR, Grütter MG, Belousova N, Mikheeva G, Krasnykh V, Plückthun A.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E869-77. doi: 10.1073/pnas.1213653110. Epub 2013 Feb 19.

PMID:
23431166
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting.

Dreier B, Mikheeva G, Belousova N, Parizek P, Boczek E, Jelesarov I, Forrer P, Plückthun A, Krasnykh V.

J Mol Biol. 2011 Jan 14;405(2):410-26. doi: 10.1016/j.jmb.2010.10.040. Epub 2010 Nov 5.

PMID:
21056576
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Adenovirus targeting to c-erbB-2 oncoprotein by single-chain antibody fused to trimeric form of adenovirus receptor ectodomain.

Kashentseva EA, Seki T, Curiel DT, Dmitriev IP.

Cancer Res. 2002 Jan 15;62(2):609-16.

PMID:
11809717
[PubMed - indexed for MEDLINE]
Free Article
5.

Tropism modification of adenovirus vectors by peptide ligand insertion into various positions of the adenovirus serotype 41 short-fiber knob domain.

Hesse A, Kosmides D, Kontermann RE, Nettelbeck DM.

J Virol. 2007 Mar;81(6):2688-99. Epub 2006 Dec 27.

PMID:
17192304
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Construction of metabolically biotinylated adenovirus with deleted fiber knob as targeting vector.

Liu Y, Valadon P, Schnitzer JE.

Virol J. 2010 Nov 12;7:316. doi: 10.1186/1743-422X-7-316.

PMID:
21073735
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Multimerization of adenovirus serotype 3 fiber knob domains is required for efficient binding of virus to desmoglein 2 and subsequent opening of epithelial junctions.

Wang H, Li Z, Yumul R, Lara S, Hemminki A, Fender P, Lieber A.

J Virol. 2011 Jul;85(13):6390-402. doi: 10.1128/JVI.00514-11. Epub 2011 Apr 27.

PMID:
21525338
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Analysis of the interaction between RGD-expressing adenovirus type 5 fiber knob domains and alphavbeta3 integrin reveals distinct binding profiles and intracellular trafficking.

Lord R, Parsons M, Kirby I, Beavil A, Hunt J, Sutton B, Santis G.

J Gen Virol. 2006 Sep;87(Pt 9):2497-505.

PMID:
16894187
[PubMed - indexed for MEDLINE]
Free Article
9.

Fiber-modified adenovirus vectors containing the TAT peptide derived from HIV-1 in the fiber knob have efficient gene transfer activity.

Kurachi S, Tashiro K, Sakurai F, Sakurai H, Kawabata K, Yayama K, Okamoto H, Nakagawa S, Mizuguchi H.

Gene Ther. 2007 Aug;14(15):1160-5. Epub 2007 May 17.

PMID:
17508008
[PubMed - indexed for MEDLINE]
10.

Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge.

Korokhov N, Mikheeva G, Krendelshchikov A, Belousova N, Simonenko V, Krendelshchikova V, Pereboev A, Kotov A, Kotova O, Triozzi PL, Aldrich WA, Douglas JT, Lo KM, Banerjee PT, Gillies SD, Curiel DT, Krasnykh V.

J Virol. 2003 Dec;77(24):12931-40.

PMID:
14645549
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Generation of fiber-modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob.

Koizumi N, Mizuguchi H, Utoguchi N, Watanabe Y, Hayakawa T.

J Gene Med. 2003 Apr;5(4):267-76.

PMID:
12692861
[PubMed - indexed for MEDLINE]
12.

The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses.

Shayakhmetov DM, Li ZY, Ternovoi V, Gaggar A, Gharwan H, Lieber A.

J Virol. 2003 Mar;77(6):3712-23.

PMID:
12610146
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation.

Koizumi N, Mizuguchi H, Sakurai F, Yamaguchi T, Watanabe Y, Hayakawa T.

J Virol. 2003 Dec;77(24):13062-72.

PMID:
14645563
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode.

Veesler D, Dreier B, Blangy S, Lichière J, Tremblay D, Moineau S, Spinelli S, Tegoni M, Plückthun A, Campanacci V, Cambillau C.

J Biol Chem. 2009 Oct 30;284(44):30718-26. doi: 10.1074/jbc.M109.037812. Epub 2009 Sep 9.

PMID:
19740746
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structural determinants for improved stability of designed ankyrin repeat proteins with a redesigned C-capping module.

Kramer MA, Wetzel SK, Plückthun A, Mittl PR, Grütter MG.

J Mol Biol. 2010 Dec 3;404(3):381-91. doi: 10.1016/j.jmb.2010.09.023. Epub 2010 Sep 17.

PMID:
20851127
[PubMed - indexed for MEDLINE]
16.

Adenovirus interaction with its cellular receptor CAR.

Howitt J, Anderson CW, Freimuth P.

Curr Top Microbiol Immunol. 2003;272:331-64. Review.

PMID:
12747555
[PubMed - indexed for MEDLINE]
17.

Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific manner.

Shayakhmetov DM, Li ZY, Gaggar A, Gharwan H, Ternovoi V, Sandig V, Lieber A.

J Virol. 2004 Sep;78(18):10009-22.

PMID:
15331734
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR.

Bewley MC, Springer K, Zhang YB, Freimuth P, Flanagan JM.

Science. 1999 Nov 19;286(5444):1579-83.

PMID:
10567268
[PubMed - indexed for MEDLINE]
Free Article
19.

Dependence of adenovirus infectivity on length of the fiber shaft domain.

Shayakhmetov DM, Lieber A.

J Virol. 2000 Nov;74(22):10274-86.

PMID:
11044071
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.

Belousova N, Krendelchtchikova V, Curiel DT, Krasnykh V.

J Virol. 2002 Sep;76(17):8621-31.

PMID:
12163581
[PubMed - indexed for MEDLINE]
Free PMC Article

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