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Items: 1 to 20 of 88

1.

Unraveling the mode of action of an obesogen: mechanistic analysis of the model obesogen tributyltin in the 3T3-L1 cell line.

Pereira-Fernandes A, Vanparys C, Hectors TL, Vergauwen L, Knapen D, Jorens PG, Blust R.

Mol Cell Endocrinol. 2013 May 6;370(1-2):52-64. doi: 10.1016/j.mce.2013.02.011. Epub 2013 Feb 18.

PMID:
23428407
2.

Toxicogenomics in the 3T3-L1 cell line, a new approach for screening of obesogenic compounds.

Pereira-Fernandes A, Vanparys C, Vergauwen L, Knapen D, Jorens PG, Blust R.

Toxicol Sci. 2014 Aug 1;140(2):352-63. doi: 10.1093/toxsci/kfu092. Epub 2014 May 20.

3.

The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes.

Li X, Ycaza J, Blumberg B.

J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):9-15. doi: 10.1016/j.jsbmb.2011.03.012. Epub 2011 Mar 21.

4.

Environmental chemical tributyltin augments adipocyte differentiation.

Inadera H, Shimomura A.

Toxicol Lett. 2005 Dec 15;159(3):226-34. Epub 2005 Jun 29.

PMID:
15993011
5.

The Mammalian "Obesogen" Tributyltin Targets Hepatic Triglyceride Accumulation and the Transcriptional Regulation of Lipid Metabolism in the Liver and Brain of Zebrafish.

Lyssimachou A, Santos JG, André A, Soares J, Lima D, Guimarães L, Almeida CM, Teixeira C, Castro LF, Santos MM.

PLoS One. 2015 Dec 3;10(12):e0143911. doi: 10.1371/journal.pone.0143911. eCollection 2015.

6.

Grape skin extract reduces adipogenesis- and lipogenesis-related gene expression in 3T3-L1 adipocytes through the peroxisome proliferator-activated receptor-γ signaling pathway.

Jeong YS, Hong JH, Cho KH, Jung HK.

Nutr Res. 2012 Jul;32(7):514-21. doi: 10.1016/j.nutres.2012.06.001. Epub 2012 Jul 18.

PMID:
22901559
7.

Obesogens, stem cells and the developmental programming of obesity.

Janesick A, Blumberg B.

Int J Androl. 2012 Jun;35(3):437-48. doi: 10.1111/j.1365-2605.2012.01247.x. Epub 2012 Feb 28. Review.

8.

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W.

Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022. Epub 2013 Mar 19.

9.

Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.

Pereira-Fernandes A, Demaegdt H, Vandermeiren K, Hectors TL, Jorens PG, Blust R, Vanparys C.

PLoS One. 2013 Oct 14;8(10):e77481. doi: 10.1371/journal.pone.0077481. eCollection 2013.

10.

Pharmacological evaluation of the mechanisms involved in increased adiposity in zebrafish triggered by the environmental contaminant tributyltin.

Ouadah-Boussouf N, Babin PJ.

Toxicol Appl Pharmacol. 2016 Mar 1;294:32-42. doi: 10.1016/j.taap.2016.01.014. Epub 2016 Jan 23.

PMID:
26812627
11.

Gene expression profiling of 3T3-L1 adipocytes exposed to phloretin.

Hassan M, El Yazidi C, Malezet-Desmoulins C, Amiot MJ, Margotat A.

J Nutr Biochem. 2010 Jul;21(7):645-52. doi: 10.1016/j.jnutbio.2009.04.006. Epub 2009 Jul 2.

PMID:
19576747
12.

Substance P decreases fat storage and increases adipocytokine production in 3T3-L1 adipocytes.

Miegueu P, St-Pierre DH, Lapointe M, Poursharifi P, Lu H, Gupta A, Cianflone K.

Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G420-7. doi: 10.1152/ajpgi.00162.2012. Epub 2012 Dec 20.

13.

Centipede grass exerts anti-adipogenic activity through inhibition of C/EBPβ, C/EBPα, and PPARγ expression and the AKT signaling pathway in 3T3-L1 adipocytes.

Park HJ, Chung BY, Lee MK, Song Y, Lee SS, Chu GM, Kang SN, Song YM, Kim GS, Cho JH.

BMC Complement Altern Med. 2012 Nov 26;12:230. doi: 10.1186/1472-6882-12-230.

14.

SH21B, an anti-obesity herbal composition, inhibits fat accumulation in 3T3-L1 adipocytes and high fat diet-induced obese mice through the modulation of the adipogenesis pathway.

Lee H, Kang R, Yoon Y.

J Ethnopharmacol. 2010 Feb 17;127(3):709-17. doi: 10.1016/j.jep.2009.12.002. Epub 2009 Dec 4.

PMID:
19963057
15.

The obesogen tributyltin.

Grün F.

Vitam Horm. 2014;94:277-325. doi: 10.1016/B978-0-12-800095-3.00011-0. Review.

PMID:
24388195
16.

(+)-Episesamin inhibits adipogenesis and exerts anti-inflammatory effects in 3T3-L1 (pre)adipocytes by sustained Wnt signaling, down-regulation of PPARγ and induction of iNOS.

Freise C, Trowitzsch-Kienast W, Erben U, Seehofer D, Kim KY, Zeitz M, Ruehl M, Somasundaram R.

J Nutr Biochem. 2013 Mar;24(3):550-5. doi: 10.1016/j.jnutbio.2012.02.004. Epub 2012 Jul 19.

PMID:
22818712
17.

Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadipocytes.

Kim KJ, Lee OH, Lee BY.

Life Sci. 2010 May 22;86(21-22):791-7. doi: 10.1016/j.lfs.2010.03.010. Epub 2010 Mar 25.

PMID:
20346961
18.

An active extract of Lindera obtusiloba inhibits adipogenesis via sustained Wnt signaling and exerts anti-inflammatory effects in the 3T3-L1 preadipocytes.

Freise C, Erben U, Neuman U, Kim K, Zeitz M, Somasundaram R, Ruehl M.

J Nutr Biochem. 2010 Dec;21(12):1170-7. doi: 10.1016/j.jnutbio.2009.09.013. Epub 2010 Jan 25.

PMID:
20092995
19.

Modulation of acute steroidogenesis, peroxisome proliferator-activated receptors and CYP3A/PXR in salmon interrenal tissues by tributyltin and the second messenger activator, forskolin.

Pavlikova N, Kortner TM, Arukwe A.

Chem Biol Interact. 2010 Apr 29;185(2):119-27. doi: 10.1016/j.cbi.2010.03.005. Epub 2010 Mar 6.

PMID:
20211155
20.

Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice.

Chamorro-García R, Sahu M, Abbey RJ, Laude J, Pham N, Blumberg B.

Environ Health Perspect. 2013 Mar;121(3):359-66. doi: 10.1289/ehp.1205701. Epub 2013 Jan 15.

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