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Items: 1 to 20 of 99


Distinct activity of BK channel β1-subunit in cerebral and pulmonary artery smooth muscle cells.

Zheng YM, Park SW, Stokes L, Tang Q, Xiao JH, Wang YX.

Am J Physiol Cell Physiol. 2013 Apr 15;304(8):C780-9. doi: 10.1152/ajpcell.00006.2012. Epub 2013 Feb 20.


Functional and molecular evidence for impairment of calcium-activated potassium channels in type-1 diabetic cerebral artery smooth muscle cells.

Dong L, Zheng YM, Van Riper D, Rathore R, Liu QH, Singer HA, Wang YX.

J Cereb Blood Flow Metab. 2008 Feb;28(2):377-86. Epub 2007 Aug 8.


Abnormal Ca2+ spark/STOC coupling in cerebral artery smooth muscle cells of obese type 2 diabetic mice.

Rueda A, Fernández-Velasco M, Benitah JP, Gómez AM.

PLoS One. 2013;8(1):e53321. doi: 10.1371/journal.pone.0053321. Epub 2013 Jan 3.


Smooth muscle cholesterol enables BK β1 subunit-mediated channel inhibition and subsequent vasoconstriction evoked by alcohol.

Bukiya AN, Vaithianathan T, Kuntamallappanavar G, Asuncion-Chin M, Dopico AM.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2410-23. doi: 10.1161/ATVBAHA.111.233965.


Activation of BKCa channel is associated with increased apoptosis of cerebrovascular smooth muscle cells in simulated microgravity rats.

Xie MJ, Ma YG, Gao F, Bai YG, Cheng JH, Chang YM, Yu ZB, Ma J.

Am J Physiol Cell Physiol. 2010 Jun;298(6):C1489-500. doi: 10.1152/ajpcell.00474.2009. Epub 2010 Mar 24.


Docosahexaenoic acid attenuates hypoxic pulmonary vasoconstriction by activating the large conductance Ca2+-activated K+ currents in pulmonary artery smooth muscle cells.

Yan J, Chen R, Liu P, Gu Y.

Pulm Pharmacol Ther. 2014 Jun;28(1):9-16. doi: 10.1016/j.pupt.2013.11.004. Epub 2013 Nov 20.


11,12-EET stimulates the association of BK channel α and β(1) subunits in mitochondria to induce pulmonary vasoconstriction.

Loot AE, Moneke I, Keserü B, Oelze M, Syzonenko T, Daiber A, Fleming I.

PLoS One. 2012;7(9):e46065. doi: 10.1371/journal.pone.0046065. Epub 2012 Sep 24.


Role of Ca(2+)-sensitive K(+) channels in the remission phase of pulmonary hypertension in chronic obstructive pulmonary diseases.

Bonnet S, Savineau JP, Barillot W, Dubuis E, Vandier C, Bonnet P.

Cardiovasc Res. 2003 Nov 1;60(2):326-36.


Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells.

Zhao G, Neeb ZP, Leo MD, Pachuau J, Adebiyi A, Ouyang K, Chen J, Jaggar JH.

J Gen Physiol. 2010 Sep;136(3):283-91. doi: 10.1085/jgp.201010453. Epub 2010 Aug 16.


The role of the large-conductance voltage-dependent and calcium-activated potassium (BK(Ca)) channels in the regulation of rat ductus arteriosus tone.

Sun F, Hayama E, Katsube Y, Matsuoka R, Nakanishi T.

Heart Vessels. 2010 Nov;25(6):556-64. doi: 10.1007/s00380-010-0008-1. Epub 2010 Oct 9.


Enhanced large conductance K+ channel activity contributes to the impaired myogenic response in the cerebral vasculature of Fawn Hooded Hypertensive rats.

Pabbidi MR, Mazur O, Fan F, Farley JM, Gebremedhin D, Harder DR, Roman RJ.

Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H989-H1000. doi: 10.1152/ajpheart.00636.2013. Epub 2014 Jan 24.


High glucose alters apoptosis and proliferation in HEK293 cells by inhibition of cloned BK Ca channel.

Chang H, Ma YG, Wang YY, Song Z, Li Q, Yang N, Zhao HZ, Feng HZ, Chang YM, Ma J, Yu ZB, Xie MJ.

J Cell Physiol. 2011 Jun;226(6):1660-75. doi: 10.1002/jcp.22497.


Requirement for functional BK channels in maintaining oscillation in venomotor tone revealed by species differences in expression of the β1 accessory subunits.

Xu H, Kandlikar SS, Westcott EB, Fink GD, Galligan JJ.

J Cardiovasc Pharmacol. 2012 Jan;59(1):29-36. doi: 10.1097/FJC.0b013e318233614c.


Long-term hypoxia increases calcium affinity of BK channels in ovine fetal and adult cerebral artery smooth muscle.

Tao X, Lin MT, Thorington GU, Wilson SM, Longo LD, Hessinger DA.

Am J Physiol Heart Circ Physiol. 2015 Apr 1;308(7):H707-22. doi: 10.1152/ajpheart.00564.2014. Epub 2015 Jan 16.


Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent.

Bukiya AN, McMillan JE, Fedinec AL, Patil SA, Miller DD, Leffler CW, Parrill AL, Dopico AM.

Mol Pharmacol. 2013 May;83(5):1030-44. doi: 10.1124/mol.112.083519. Epub 2013 Mar 1.


Daidzein relaxes rat cerebral basilar artery via activation of large-conductance Ca2+-activated K+ channels in vascular smooth muscle cells.

Zhang HT, Wang Y, Deng XL, Dong MQ, Zhao LM, Wang YW.

Eur J Pharmacol. 2010 Mar 25;630(1-3):100-6. doi: 10.1016/j.ejphar.2009.12.032. Epub 2010 Jan 5.


Altered L-type Ca2+ channel activity contributes to exacerbated hypoperfusion and mortality in smooth muscle cell BK channel-deficient septic mice.

Xu H, Garver H, Fernandes R, Galligan JJ, Fink GD.

Am J Physiol Regul Integr Comp Physiol. 2014 Jul 15;307(2):R138-48.


Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits.

Resnik E, Herron J, Fu R, Ivy DD, Cornfield DN.

Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L761-L768. Epub 2005 Nov 11.


Characterization of voltage-and Ca2+-activated K+ channels in rat dorsal root ganglion neurons.

Li W, Gao SB, Lv CX, Wu Y, Guo ZH, Ding JP, Xu T.

J Cell Physiol. 2007 Aug;212(2):348-57.


Large-conductance voltage- and Ca2+-activated K+ channels regulate human detrusor smooth muscle function.

Hristov KL, Chen M, Kellett WF, Rovner ES, Petkov GV.

Am J Physiol Cell Physiol. 2011 Oct;301(4):C903-12. doi: 10.1152/ajpcell.00495.2010. Epub 2011 Jun 22.

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