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Results: 1 to 20 of 109

1.

Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.

Shafqat N, Muniz JR, Pilka ES, Papagrigoriou E, von Delft F, Oppermann U, Yue WW.

Biochem J. 2013 May 15;452(1):27-36. doi: 10.1042/BJ20121580.

PMID:
23425511
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of S-adenosylmethionine synthesis from ATP and Met.

Komoto J, Yamada T, Takata Y, Markham GD, Takusagawa F.

Biochemistry. 2004 Feb 24;43(7):1821-31.

PMID:
14967023
[PubMed - indexed for MEDLINE]
3.

Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism.

González B, Pajares MA, Hermoso JA, Guillerm D, Guillerm G, Sanz-Aparicio J.

J Mol Biol. 2003 Aug 8;331(2):407-16.

PMID:
12888348
[PubMed - indexed for MEDLINE]
4.

Methionine adenosyltransferase 2A/2B and methylation: gene sequence variation and functional genomics.

Nordgren KK, Peng Y, Pelleymounter LL, Moon I, Abo R, Feng Q, Eckloff B, Yee VC, Wieben E, Weinshilboum RM.

Drug Metab Dispos. 2011 Nov;39(11):2135-47. doi: 10.1124/dmd.111.040857. Epub 2011 Aug 3.

PMID:
21813468
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat.

Huang ZZ, Mato JM, Kanel G, Lu SC.

Hepatology. 1999 May;29(5):1471-8.

PMID:
10216131
[PubMed - indexed for MEDLINE]
6.

S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver.

García-Trevijano ER, Latasa MU, Carretero MV, Berasain C, Mato JM, Avila MA.

FASEB J. 2000 Dec;14(15):2511-8.

PMID:
11099469
[PubMed - indexed for MEDLINE]
Free Article
7.

Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.

Lu SC, Mato JM.

Alcohol. 2005 Apr;35(3):227-34. Review.

PMID:
16054984
[PubMed - indexed for MEDLINE]
8.

Structure-function relationships in methionine adenosyltransferases.

Markham GD, Pajares MA.

Cell Mol Life Sci. 2009 Feb;66(4):636-48. doi: 10.1007/s00018-008-8516-1. Review.

PMID:
18953685
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The crystal structure of tetrameric methionine adenosyltransferase from rat liver reveals the methionine-binding site.

González B, Pajares MA, Hermoso JA, Alvarez L, Garrido F, Sufrin JR, Sanz-Aparicio J.

J Mol Biol. 2000 Jul 7;300(2):363-75.

PMID:
10873471
[PubMed - indexed for MEDLINE]
10.

Metabolic aspects of epigenome: coupling of S-adenosylmethionine synthesis and gene regulation on chromatin by SAMIT module.

Igarashi K, Katoh Y.

Subcell Biochem. 2013;61:105-18. doi: 10.1007/978-94-007-4525-4_5. Review.

PMID:
23150248
[PubMed - indexed for MEDLINE]
11.

Structure and function of S-adenosylmethionine synthetase: crystal structures of S-adenosylmethionine synthetase with ADP, BrADP, and PPi at 28 angstroms resolution.

Takusagawa F, Kamitori S, Markham GD.

Biochemistry. 1996 Feb 27;35(8):2586-96.

PMID:
8611562
[PubMed - indexed for MEDLINE]
12.

Regulation of mammalian liver methionine adenosyltransferase.

Corrales FJ, Pérez-Mato I, Sánchez Del Pino MM, Ruiz F, Castro C, García-Trevijano ER, Latasa U, Martínez-Chantar ML, Martínez-Cruz A, Avila MA, Mato JM.

J Nutr. 2002 Aug;132(8 Suppl):2377S-2381S.

PMID:
12163696
[PubMed - indexed for MEDLINE]
Free Article
14.

NADP+ binding to the regulatory subunit of methionine adenosyltransferase II increases intersubunit binding affinity in the hetero-trimer.

González B, Garrido F, Ortega R, Martínez-Júlvez M, Revilla-Guarinos A, Pérez-Pertejo Y, Velázquez-Campoy A, Sanz-Aparicio J, Pajares MA.

PLoS One. 2012;7(11):e50329. doi: 10.1371/journal.pone.0050329. Epub 2012 Nov 26.

PMID:
23189196
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer.

Yang H, Huang ZZ, Zeng Z, Chen C, Selby RR, Lu SC.

Am J Physiol Gastrointest Liver Physiol. 2001 Feb;280(2):G184-90.

PMID:
11208539
[PubMed - indexed for MEDLINE]
Free Article
16.

S-adenosylmethionine synthesis: molecular mechanisms and clinical implications.

Mato JM, Alvarez L, Ortiz P, Pajares MA.

Pharmacol Ther. 1997;73(3):265-80. Review.

PMID:
9175157
[PubMed - indexed for MEDLINE]
17.

MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth.

Lo TF, Tsai WC, Chen ST.

PLoS One. 2013 Sep 30;8(9):e75628. doi: 10.1371/journal.pone.0075628. eCollection 2013.

PMID:
24098708
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

DNA methylation and histone acetylation of rat methionine adenosyltransferase 1A and 2A genes is tissue-specific.

Torre L, López-Rodas G, Latasa MU, Carretero MV, Boukaba A, Rodríguez JL, Franco L, Mato JM, Avila MA.

Int J Biochem Cell Biol. 2000 Apr;32(4):397-404.

PMID:
10762065
[PubMed - indexed for MEDLINE]
19.

Regulation of the human MAT2B gene encoding the regulatory beta subunit of methionine adenosyltransferase, MAT II.

LeGros L, Halim AB, Chamberlin ME, Geller A, Kotb M.

J Biol Chem. 2001 Jul 6;276(27):24918-24. Epub 2001 May 3.

PMID:
11337507
[PubMed - indexed for MEDLINE]
Free Article
20.

Flexible loop in the structure of S-adenosylmethionine synthetase crystallized in the tetragonal modification.

Fu Z, Hu Y, Markham GD, Takusagawa F.

J Biomol Struct Dyn. 1996 Apr;13(5):727-39.

PMID:
8723769
[PubMed - indexed for MEDLINE]

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