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Results: 1 to 20 of 237

1.

Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer.

Lin YW, Ren LL, Xiong H, Du W, Yu YN, Sun TT, Weng YR, Wang ZH, Wang JL, Wang YC, Cui Y, Sun DF, Han ZG, Shen N, Zou W, Xu J, Chen HY, Cao W, Hong J, Fang JY.

J Pathol. 2013 Jul;230(3):277-90. doi: 10.1002/path.4179.

PMID:
23424038
[PubMed - indexed for MEDLINE]
2.

Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, β-catenin and EZH2.

Weng YR, Yu YN, Ren LL, Cui Y, Lu YY, Chen HY, Ma X, Qin WX, Cao W, Hong J, Fang JY.

Carcinogenesis. 2014 Jun;35(6):1389-98. doi: 10.1093/carcin/bgu057. Epub 2014 Mar 6.

PMID:
24608043
[PubMed - indexed for MEDLINE]
3.

Epigenetic regulation of cell adhesion and communication by enhancer of zeste homolog 2 in human endothelial cells.

Dreger H, Ludwig A, Weller A, Stangl V, Baumann G, Meiners S, Stangl K.

Hypertension. 2012 Nov;60(5):1176-83. doi: 10.1161/HYPERTENSIONAHA.112.191098. Epub 2012 Sep 10.

PMID:
22966008
[PubMed - indexed for MEDLINE]
Free Article
4.

Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition.

Xiong H, Hong J, Du W, Lin YW, Ren LL, Wang YC, Su WY, Wang JL, Cui Y, Wang ZH, Fang JY.

J Biol Chem. 2012 Feb 17;287(8):5819-32. doi: 10.1074/jbc.M111.295964. Epub 2011 Dec 28.

PMID:
22205702
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.

Xia H, Ooi LL, Hui KM.

PLoS One. 2012;7(9):e44206. doi: 10.1371/journal.pone.0044206. Epub 2012 Sep 4. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/1be2a62e-45a1-4c13-9a8d-f265005a21e0.

PMID:
22962603
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer.

Kodach LL, Jacobs RJ, Heijmans J, van Noesel CJ, Langers AM, Verspaget HW, Hommes DW, Offerhaus GJ, van den Brink GR, Hardwick JC.

Carcinogenesis. 2010 Sep;31(9):1567-75. doi: 10.1093/carcin/bgq147. Epub 2010 Jul 14.

PMID:
20631058
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).

McCabe MT, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y, Smitheman KN, Ott HM, Pappalardi MB, Allen KE, Chen SB, Della Pietra A 3rd, Dul E, Hughes AM, Gilbert SA, Thrall SH, Tummino PJ, Kruger RG, Brandt M, Schwartz B, Creasy CL.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2989-94. doi: 10.1073/pnas.1116418109. Epub 2012 Feb 8.

PMID:
22323599
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.

Kogure M, Takawa M, Saloura V, Sone K, Piao L, Ueda K, Ibrahim R, Tsunoda T, Sugiyama M, Atomi Y, Nakamura Y, Hamamoto R.

Neoplasia. 2013 Nov;15(11):1251-61.

PMID:
24339737
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.

Yokoyama Y, Hieda M, Nishioka Y, Matsumoto A, Higashi S, Kimura H, Yamamoto H, Mori M, Matsuura S, Matsuura N.

Cancer Sci. 2013 Jul;104(7):889-95. doi: 10.1111/cas.12166. Epub 2013 May 15.

PMID:
23557258
[PubMed - indexed for MEDLINE]
10.

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer.

Asangani IA, Ateeq B, Cao Q, Dodson L, Pandhi M, Kunju LP, Mehra R, Lonigro RJ, Siddiqui J, Palanisamy N, Wu YM, Cao X, Kim JH, Zhao M, Qin ZS, Iyer MK, Maher CA, Kumar-Sinha C, Varambally S, Chinnaiyan AM.

Mol Cell. 2013 Jan 10;49(1):80-93. doi: 10.1016/j.molcel.2012.10.008. Epub 2012 Nov 15.

PMID:
23159737
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation.

Fujii S, Ito K, Ito Y, Ochiai A.

J Biol Chem. 2008 Jun 20;283(25):17324-32. doi: 10.1074/jbc.M800224200. Epub 2008 Apr 22.

PMID:
18430739
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer.

Chen H, Tu SW, Hsieh JT.

J Biol Chem. 2005 Jun 10;280(23):22437-44. Epub 2005 Apr 6.

PMID:
15817459
[PubMed - indexed for MEDLINE]
Free Article
13.

The histone H3K27 methylation mark regulates intestinal epithelial cell density-dependent proliferation and the inflammatory response.

Turgeon N, Blais M, Delabre JF, Asselin C.

J Cell Biochem. 2013 May;114(5):1203-15. doi: 10.1002/jcb.24463.

PMID:
23192652
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo.

Hu S, Yu L, Li Z, Shen Y, Wang J, Cai J, Xiao L, Wang Z.

Cancer Biol Ther. 2010 Oct 15;10(8):788-95. Epub 2010 Oct 15.

PMID:
20686362
[PubMed - indexed for MEDLINE]
Free Article
15.

Enhancer of zeste homolog 2 promotes the proliferation and invasion of epithelial ovarian cancer cells.

Li H, Cai Q, Godwin AK, Zhang R.

Mol Cancer Res. 2010 Dec;8(12):1610-8. doi: 10.1158/1541-7786.MCR-10-0398. Epub 2010 Nov 29.

PMID:
21115743
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.

Liang L, Li X, Zhang X, Lv Z, He G, Zhao W, Ren X, Li Y, Bian X, Liao W, Liu W, Yang G, Ding Y.

Gastroenterology. 2013 Mar;144(3):624-635.e4. doi: 10.1053/j.gastro.2012.11.033. Epub 2012 Nov 27.

PMID:
23201162
[PubMed - indexed for MEDLINE]
17.

Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer.

Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, Bazeley PS, Beshir AB, Fenteany G, Mehra R, Daignault S, Al-Mulla F, Keller E, Bonavida B, de la Serna I, Yeung KC.

Cancer Res. 2012 Jun 15;72(12):3091-104. doi: 10.1158/0008-5472.CAN-11-3546. Epub 2012 Apr 13.

PMID:
22505648
[PubMed - indexed for MEDLINE]
Free Article
18.

Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

Holm K, Grabau D, Lövgren K, Aradottir S, Gruvberger-Saal S, Howlin J, Saal LH, Ethier SP, Bendahl PO, Stål O, Malmström P, Fernö M, Rydén L, Hegardt C, Borg Å, Ringnér M.

Mol Oncol. 2012 Oct;6(5):494-506. doi: 10.1016/j.molonc.2012.06.002. Epub 2012 Jun 20.

PMID:
22766277
[PubMed - indexed for MEDLINE]
Free Article
19.

EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of histone methyltransferase activity.

Yan J, Ng SB, Tay JL, Lin B, Koh TL, Tan J, Selvarajan V, Liu SC, Bi C, Wang S, Choo SN, Shimizu N, Huang G, Yu Q, Chng WJ.

Blood. 2013 May 30;121(22):4512-20. doi: 10.1182/blood-2012-08-450494. Epub 2013 Mar 25.

PMID:
23529930
[PubMed - indexed for MEDLINE]
Free Article
20.

Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.

Xiong H, Zhang ZG, Tian XQ, Sun DF, Liang QC, Zhang YJ, Lu R, Chen YX, Fang JY.

Neoplasia. 2008 Mar;10(3):287-97.

PMID:
18320073
[PubMed - indexed for MEDLINE]
Free PMC Article

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