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CDK inhibitor p57 (Kip2) is downregulated by Akt during HER2-mediated tumorigenicity.

Zhao R, Yang HY, Shin J, Phan L, Fang L, Che TF, Su CH, Yeung SC, Lee MH.

Cell Cycle. 2013 Mar 15;12(6):935-43. doi: 10.4161/cc.23883. Epub 2013 Feb 19.


Characteristic expression of p57/Kip2 in balloon cells in focal cortical dysplasia.

Kimura T, Kitaura H, Masuda H, Kameyama S, Saito Y, Sugai K, Otsuki T, Nakazawa A, Morota N, Yamamoto T, Iida K, Nakagawa M, Mizuno T, Takahashi H, Kakita A.

Neuropathology. 2015 May 7. doi: 10.1111/neup.12199. [Epub ahead of print]


Regulating the stability and localization of CDK inhibitor p27Kip1 via CSN6-COP1 axis.

Choi HH, Guma S, Fang L, Phan L, Ivan C, Baggerly K, Sood A, Lee MH.

Cell Cycle. 2015 May 6:1-9. [Epub ahead of print]


ATM kinase sustains HER2 tumorigenicity in breast cancer.

Stagni V, Manni I, Oropallo V, Mottolese M, Di Benedetto A, Piaggio G, Falcioni R, Giaccari D, Di Carlo S, Sperati F, Cencioni MT, Barilà D.

Nat Commun. 2015 Apr 16;6:6886. doi: 10.1038/ncomms7886.


[Expression of p57(kip2) gene in placenta tissue of patients with pre-eclampsia].

He GL, Xu WM, Liu XH.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2015 Jan;46(1):123-8. Chinese. No abstract available.


Akt-Girdin signaling in cancer-associated fibroblasts contributes to tumor progression.

Yamamura Y, Asai N, Enomoto A, Kato T, Mii S, Kondo Y, Ushida K, Niimi K, Tsunoda N, Nagino M, Ichihara S, Furukawa K, Maeda K, Murohara T, Takahashi M.

Cancer Res. 2015 Mar 1;75(5):813-23. doi: 10.1158/0008-5472.CAN-14-1317.


Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes.

Ju JH, Oh S, Lee KM, Yang W, Nam KS, Moon HG, Noh DY, Kim CG, Park G, Park JB, Lee T, Arteaga CL, Shin I.

Cell Death Differ. 2015 Apr;22(4):665-76. doi: 10.1038/cdd.2014.155. Epub 2014 Oct 24.


Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer.

Yaglom JA, McFarland C, Mirny L, Sherman MY.

Oncotarget. 2014 Sep 30;5(18):8367-78.


MicroRNA-21 inhibits p57Kip2 expression in prostate cancer.

Mishra S, Lin CL, Huang TH, Bouamar H, Sun LZ.

Mol Cancer. 2014 Sep 12;13:212. doi: 10.1186/1476-4598-13-212.


The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes.

Wang HM, Xu YF, Ning SL, Yang DX, Li Y, Du YJ, Yang F, Zhang Y, Liang N, Yao W, Zhang LL, Gu LC, Gao CJ, Pang Q, Chen YX, Xiao KH, Ma R, Yu X, Sun JP.

Cell Res. 2014 Sep;24(9):1067-90. doi: 10.1038/cr.2014.99. Epub 2014 Aug 1.


A mechanistic role for the chromatin modulator, NAP1L1, in pancreatic neuroendocrine neoplasm proliferation and metastases.

Schimmack S, Taylor A, Lawrence B, Alaimo D, Schmitz-Winnenthal H, Büchler MW, Modlin IM, Kidd M.

Epigenetics Chromatin. 2014 Jul 21;7:15. doi: 10.1186/1756-8935-7-15. eCollection 2014.


p57(Kip2) regulates T-cell development and lymphoma.

Jayapal SR, Kaldis P.

Blood. 2014 May 29;123(22):3370-1. doi: 10.1182/blood-2014-04-565309. No abstract available.


Correlation between PDZK1, Cdc37, Akt and breast cancer malignancy: the role of PDZK1 in cell growth through Akt stabilization by increasing and interacting with Cdc37.

Kim H, Abd Elmageed ZY, Davis C, El-Bahrawy AH, Naura AS, Ekaidi I, Abdel-Mageed AB, Boulares AH.

Mol Med. 2014 Jul 14;20:270-9. doi: 10.2119/molmed.2013.00166.


Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis.

de Renty C, DePamphilis ML, Ullah Z.

PLoS One. 2014 May 21;9(5):e97434. doi: 10.1371/journal.pone.0097434. eCollection 2014.


Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells.

Jung S, Ohk J, Jeong D, Li C, Lee S, Duan J, Kim C, Lim JS, Yang Y, Kim KI, Lee MS.

Int J Oncol. 2014 Jul;45(1):189-96. doi: 10.3892/ijo.2014.2403. Epub 2014 Apr 28.


Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells.

Hosonaga M, Arima Y, Sugihara E, Kohno N, Saya H.

Cancer Sci. 2014 Jul;105(7):779-87. doi: 10.1111/cas.12427. Epub 2014 Jun 2.


p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling.

Matsumoto A, Takeishi S, Nakayama KI.

Blood. 2014 May 29;123(22):3429-39. doi: 10.1182/blood-2013-10-532390. Epub 2014 Mar 20.


Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway.

Fusella F, Ferretti R, Recupero D, Rocca S, Di Savino A, Tornillo G, Silengo L, Turco E, Cabodi S, Provero P, Pandolfi PP, Sapino A, Tarone G, Brancaccio M.

J Pathol. 2014 Oct;234(2):152-63. doi: 10.1002/path.4341. Epub 2014 Aug 6.


S100A14, a member of the EF-hand calcium-binding proteins, is overexpressed in breast cancer and acts as a modulator of HER2 signaling.

Xu C, Chen H, Wang X, Gao J, Che Y, Li Y, Ding F, Luo A, Zhang S, Liu Z.

J Biol Chem. 2014 Jan 10;289(2):827-37. doi: 10.1074/jbc.M113.469718. Epub 2013 Nov 27.


Deubiquitylation and stabilization of PTEN by USP13.

Zhang J, Zhang P, Wei Y, Piao HL, Wang W, Maddika S, Wang M, Chen D, Sun Y, Hung MC, Chen J, Ma L.

Nat Cell Biol. 2013 Dec;15(12):1486-94. doi: 10.1038/ncb2874. Epub 2013 Nov 24.

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