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Results: 1 to 20 of 145

1.

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.

Tschaharganeh DF, Chen X, Latzko P, Malz M, Gaida MM, Felix K, Ladu S, Singer S, Pinna F, Gretz N, Sticht C, Tomasi ML, Delogu S, Evert M, Fan B, Ribback S, Jiang L, Brozzetti S, Bergmann F, Dombrowski F, Schirmacher P, Calvisi DF, Breuhahn K.

Gastroenterology. 2013 Jun;144(7):1530-1542.e12. doi: 10.1053/j.gastro.2013.02.009. Epub 2013 Feb 16.

PMID:
23419361
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

RASSF1A-mediated regulation of AREG via the Hippo pathway in hepatocellular carcinoma.

Ahn EY, Kim JS, Kim GJ, Park YN.

Mol Cancer Res. 2013 Jul;11(7):748-58. doi: 10.1158/1541-7786.MCR-12-0665. Epub 2013 Apr 17.

PMID:
23594797
[PubMed - indexed for MEDLINE]
Free Article
3.

Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells.

Zhang T, Zhang J, You X, Liu Q, Du Y, Gao Y, Shan C, Kong G, Wang Y, Yang X, Ye L, Zhang X.

Hepatology. 2012 Dec;56(6):2051-9. doi: 10.1002/hep.25899. Epub 2012 Nov 13.

PMID:
22707013
[PubMed - indexed for MEDLINE]
4.

AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma.

Xu MZ, Chan SW, Liu AM, Wong KF, Fan ST, Chen J, Poon RT, Zender L, Lowe SW, Hong W, Luk JM.

Oncogene. 2011 Mar 10;30(10):1229-40. doi: 10.1038/onc.2010.504. Epub 2010 Nov 15.

PMID:
21076472
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP.

Miao HL, Pan ZJ, Lei CJ, Wen JY, Li MY, Liu ZK, Qiu ZD, Lin MZ, Chen NP, Chen M.

J Cell Biochem. 2013 Mar;114(3):625-31. doi: 10.1002/jcb.24404.

PMID:
23060277
[PubMed - indexed for MEDLINE]
6.

Wnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells.

Konsavage WM Jr, Kyler SL, Rennoll SA, Jin G, Yochum GS.

J Biol Chem. 2012 Apr 6;287(15):11730-9. doi: 10.1074/jbc.M111.327767. Epub 2012 Feb 15.

PMID:
22337891
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53.

Bai N, Zhang C, Liang N, Zhang Z, Chang A, Yin J, Li Z, Luo N, Tan X, Luo N, Luo Y, Xiang R, Li X, Reisfeld RA, Stupack D, Lv D, Liu C.

Cancer Biol Ther. 2013 Jun;14(6):511-20. doi: 10.4161/cbt.24345.

PMID:
23760493
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system.

Latasa MU, Salis F, Urtasun R, Garcia-Irigoyen O, Elizalde M, Uriarte I, Santamaria M, Feo F, Pascale RM, Prieto J, Berasain C, Avila MA.

PLoS One. 2012;7(12):e52711. doi: 10.1371/journal.pone.0052711. Epub 2012 Dec 20.

PMID:
23285165
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity.

Shimomura T, Miyamura N, Hata S, Miura R, Hirayama J, Nishina H.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):917-23. doi: 10.1016/j.bbrc.2013.12.100. Epub 2013 Dec 28.

PMID:
24380865
[PubMed - indexed for MEDLINE]
10.

YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor.

Zhi X, Zhao D, Zhou Z, Liu R, Chen C.

Am J Pathol. 2012 Jun;180(6):2452-61. doi: 10.1016/j.ajpath.2012.02.025.

PMID:
22632819
[PubMed - indexed for MEDLINE]
11.

Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma.

Huo X, Zhang Q, Liu AM, Tang C, Gong Y, Bian J, Luk JM, Xu Z, Chen J.

Oncol Rep. 2013 Feb;29(2):840-6. doi: 10.3892/or.2012.2176. Epub 2012 Dec 10.

PMID:
23232767
[PubMed - indexed for MEDLINE]
12.

Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice.

Kowalik MA, Saliba C, Pibiri M, Perra A, Ledda-Columbano GM, Sarotto I, Ghiso E, Giordano S, Columbano A.

Hepatology. 2011 Jun;53(6):2086-96. doi: 10.1002/hep.24289. Epub 2011 May 13.

PMID:
21391223
[PubMed - indexed for MEDLINE]
13.

The miR-143/145 cluster is a novel transcriptional target of Jagged-1/Notch signaling in vascular smooth muscle cells.

Boucher JM, Peterson SM, Urs S, Zhang C, Liaw L.

J Biol Chem. 2011 Aug 12;286(32):28312-21. doi: 10.1074/jbc.M111.221945. Epub 2011 Jun 17. Erratum in: J Biol Chem. 2012 May 25;287(22):18585.

PMID:
21685392
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Notch signalling beyond liver development: emerging concepts in liver repair and oncogenesis.

Morell CM, Fiorotto R, Fabris L, Strazzabosco M.

Clin Res Hepatol Gastroenterol. 2013 Nov;37(5):447-54. doi: 10.1016/j.clinre.2013.05.008. Epub 2013 Jun 24. Review.

PMID:
23806629
[PubMed - indexed for MEDLINE]
15.

GSI-I has a better effect in inhibiting hepatocellular carcinoma cell growth than GSI-IX, GSI-X, or GSI-XXI.

Shen Y, Lv D, Wang J, Yin Y, Miao F, Dou F, Zhang J.

Anticancer Drugs. 2012 Aug;23(7):683-90. doi: 10.1097/CAD.0b013e3283549a22.

PMID:
22569108
[PubMed - indexed for MEDLINE]
16.

Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.

Nishina S, Shiraha H, Nakanishi Y, Tanaka S, Matsubara M, Takaoka N, Uemura M, Horiguchi S, Kataoka J, Iwamuro M, Yagi T, Yamamoto K.

Oncol Rep. 2011 Sep;26(3):523-31. doi: 10.3892/or.2011.1336. Epub 2011 May 31.

PMID:
21637926
[PubMed - indexed for MEDLINE]
17.

Deregulation of Hippo kinase signalling in human hepatic malignancies.

Li H, Wolfe A, Septer S, Edwards G, Zhong X, Abdulkarim AB, Ranganathan S, Apte U.

Liver Int. 2012 Jan;32(1):38-47. doi: 10.1111/j.1478-3231.2011.02646.x. Epub 2011 Oct 20.

PMID:
22098159
[PubMed - indexed for MEDLINE]
18.

Neuron-derived orphan receptor 1 promotes proliferation of quiescent hepatocytes.

Vacca M, Murzilli S, Salvatore L, Di Tullio G, D'Orazio A, Lo Sasso G, Graziano G, Pinzani M, Chieppa M, Mariani-Costantini R, Palasciano G, Moschetta A.

Gastroenterology. 2013 Jun;144(7):1518-1529.e3. doi: 10.1053/j.gastro.2013.02.027. Epub 2013 Feb 24.

PMID:
23462179
[PubMed - indexed for MEDLINE]
19.

Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice.

Villanueva A, Alsinet C, Yanger K, Hoshida Y, Zong Y, Toffanin S, Rodriguez-Carunchio L, Solé M, Thung S, Stanger BZ, Llovet JM.

Gastroenterology. 2012 Dec;143(6):1660-1669.e7. doi: 10.1053/j.gastro.2012.09.002. Epub 2012 Sep 11.

PMID:
22974708
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade.

Ma J, Meng Y, Kwiatkowski DJ, Chen X, Peng H, Sun Q, Zha X, Wang F, Wang Y, Jing Y, Zhang S, Chen R, Wang L, Wu E, Cai G, Malinowska-Kolodziej I, Liao Q, Liu Y, Zhao Y, Sun Q, Xu K, Dai J, Han J, Wu L, Zhao RC, Shen H, Zhang H.

J Clin Invest. 2010 Jan;120(1):103-14. doi: 10.1172/JCI37964. Epub 2009 Dec 28.

PMID:
20038814
[PubMed - indexed for MEDLINE]
Free PMC Article

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