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Results: 1 to 20 of 95

1.

Activation of GCN2 upon HIV-1 infection and inhibition of translation.

Cosnefroy O, Jaspart A, Calmels C, Parissi V, Fleury H, Ventura M, Reigadas S, Andréola ML.

Cell Mol Life Sci. 2013 Jul;70(13):2411-21. doi: 10.1007/s00018-013-1272-x. Epub 2013 Feb 17.

PMID:
23417324
[PubMed - indexed for MEDLINE]
2.

GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection.

del Pino J, Jiménez JL, Ventoso I, Castelló A, Muñoz-Fernández MÁ, de Haro C, Berlanga JJ.

PLoS One. 2012;7(10):e47272. doi: 10.1371/journal.pone.0047272. Epub 2012 Oct 23.

PMID:
23110064
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses.

Berlanga JJ, Ventoso I, Harding HP, Deng J, Ron D, Sonenberg N, Carrasco L, de Haro C.

EMBO J. 2006 Apr 19;25(8):1730-40. Epub 2006 Apr 6.

PMID:
16601681
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

New functions of protein kinase Gcn2 in yeast and mammals.

Murguía JR, Serrano R.

IUBMB Life. 2012 Dec;64(12):971-4. doi: 10.1002/iub.1090. Epub 2012 Nov 5. Review.

PMID:
23129244
[PubMed - indexed for MEDLINE]
5.

Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity.

Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E.

J Virol. 2009 Mar;83(5):2298-309. doi: 10.1128/JVI.01245-08. Epub 2008 Dec 24.

PMID:
19109397
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.
8.

Activation of GCN2 in UV-irradiated cells inhibits translation.

Deng J, Harding HP, Raught B, Gingras AC, Berlanga JJ, Scheuner D, Kaufman RJ, Ron D, Sonenberg N.

Curr Biol. 2002 Aug 6;12(15):1279-86.

PMID:
12176355
[PubMed - indexed for MEDLINE]
Free Article
9.

Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2.

Wek RC, Cannon JF, Dever TE, Hinnebusch AG.

Mol Cell Biol. 1992 Dec;12(12):5700-10.

PMID:
1333044
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.

Marton MJ, Vazquez de Aldana CR, Qiu H, Chakraburtty K, Hinnebusch AG.

Mol Cell Biol. 1997 Aug;17(8):4474-89.

PMID:
9234705
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The eIF-2alpha kinases and the control of protein synthesis.

de Haro C, Méndez R, Santoyo J.

FASEB J. 1996 Oct;10(12):1378-87. Review.

PMID:
8903508
[PubMed - indexed for MEDLINE]
Free Article
12.

A new functional role of HIV-1 integrase during uncoating of the viral core.

Briones MS, Chow SA.

Immunol Res. 2010 Dec;48(1-3):14-26. doi: 10.1007/s12026-010-8164-z.

PMID:
20721640
[PubMed - indexed for MEDLINE]
13.

The roles of stress-activated Sty1 and Gcn2 kinases and of the protooncoprotein homologue Int6/eIF3e in responses to endogenous oxidative stress during histidine starvation.

Nemoto N, Udagawa T, Ohira T, Jiang L, Hirota K, Wilkinson CR, Bähler J, Jones N, Ohta K, Wek RC, Asano K.

J Mol Biol. 2010 Nov 26;404(2):183-201. doi: 10.1016/j.jmb.2010.09.016. Epub 2010 Sep 25.

PMID:
20875427
[PubMed - indexed for MEDLINE]
14.

Increased susceptibility to DNA virus infection in mice with a GCN2 mutation.

Won S, Eidenschenk C, Arnold CN, Siggs OM, Sun L, Brandl K, Mullen TM, Nemerow GR, Moresco EM, Beutler B.

J Virol. 2012 Feb;86(3):1802-8. doi: 10.1128/JVI.05660-11. Epub 2011 Nov 23.

PMID:
22114338
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase.

Lau A, Swinbank KM, Ahmed PS, Taylor DL, Jackson SP, Smith GC, O'Connor MJ.

Nat Cell Biol. 2005 May;7(5):493-500. Epub 2005 Apr 17.

PMID:
15834407
[PubMed - indexed for MEDLINE]
16.

YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.

Sattlegger E, Swanson MJ, Ashcraft EA, Jennings JL, Fekete RA, Link AJ, Hinnebusch AG.

J Biol Chem. 2004 Jul 16;279(29):29952-62. Epub 2004 May 4.

PMID:
15126500
[PubMed - indexed for MEDLINE]
Free Article
17.

Role of phosphorylation in the nuclear biology of HIV-1.

Francis AC, Di Primio C, Allouch A, Cereseto A.

Curr Med Chem. 2011;18(19):2904-12. Review.

PMID:
21651489
[PubMed - indexed for MEDLINE]
18.
19.

MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells.

Thiaville MM, Pan YX, Gjymishka A, Zhong C, Kaufman RJ, Kilberg MS.

J Biol Chem. 2008 Apr 18;283(16):10848-57. doi: 10.1074/jbc.M708320200. Epub 2008 Feb 20.

PMID:
18287093
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation.

Sattlegger E, Hinnebusch AG.

J Biol Chem. 2005 Apr 22;280(16):16514-21. Epub 2005 Feb 18.

PMID:
15722345
[PubMed - indexed for MEDLINE]
Free Article

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