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Items: 1 to 20 of 144

1.

Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.

Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV Jr, Walther TC.

Dev Cell. 2013 Feb 25;24(4):384-99. doi: 10.1016/j.devcel.2013.01.013. Epub 2013 Feb 14.

2.

An ER protein functionally couples neutral lipid metabolism on lipid droplets to membrane lipid synthesis in the ER.

Markgraf DF, Klemm RW, Junker M, Hannibal-Bach HK, Ejsing CS, Rapoport TA.

Cell Rep. 2014 Jan 16;6(1):44-55. doi: 10.1016/j.celrep.2013.11.046. Epub 2013 Dec 27.

3.

Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae.

Jacquier N, Choudhary V, Mari M, Toulmay A, Reggiori F, Schneiter R.

J Cell Sci. 2011 Jul 15;124(Pt 14):2424-37. doi: 10.1242/jcs.076836. Epub 2011 Jun 21.

4.

Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum.

McFie PJ, Banman SL, Kary S, Stone SJ.

J Biol Chem. 2011 Aug 12;286(32):28235-46. doi: 10.1074/jbc.M111.256008. Epub 2011 Jun 16.

5.

Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting.

Wilfling F, Thiam AR, Olarte MJ, Wang J, Beck R, Gould TJ, Allgeyer ES, Pincet F, Bewersdorf J, Farese RV Jr, Walther TC.

Elife. 2014;3:e01607. doi: 10.7554/eLife.01607. Epub 2014 Feb 4.

6.

The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface.

Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV Jr, Mak HY.

J Cell Biol. 2012 Sep 3;198(5):895-911. doi: 10.1083/jcb.201201139. Epub 2012 Aug 27.

7.

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes.

Harris CA, Haas JT, Streeper RS, Stone SJ, Kumari M, Yang K, Han X, Brownell N, Gross RW, Zechner R, Farese RV Jr.

J Lipid Res. 2011 Apr;52(4):657-67. doi: 10.1194/jlr.M013003. Epub 2011 Feb 11.

8.

Diacylglycerol acyltransferase-2 (DGAT2) and monoacylglycerol acyltransferase-2 (MGAT2) interact to promote triacylglycerol synthesis.

Jin Y, McFie PJ, Banman SL, Brandt C, Stone SJ.

J Biol Chem. 2014 Oct 10;289(41):28237-48. doi: 10.1074/jbc.M114.571190. Epub 2014 Aug 27.

9.

Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.

Takahashi Y, Shinoda A, Furuya N, Harada E, Arimura N, Ichi I, Fujiwara Y, Inoue J, Sato R.

PLoS One. 2013 May 29;8(5):e64605. doi: 10.1371/journal.pone.0064605. Print 2013.

10.

Expression of oleosin and perilipins in yeast promotes formation of lipid droplets from the endoplasmic reticulum.

Jacquier N, Mishra S, Choudhary V, Schneiter R.

J Cell Sci. 2013 Nov 15;126(Pt 22):5198-209. doi: 10.1242/jcs.131896. Epub 2013 Sep 4.

11.

Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression.

Wang H, Wei E, Quiroga AD, Sun X, Touret N, Lehner R.

Mol Biol Cell. 2010 Jun 15;21(12):1991-2000. doi: 10.1091/mbc.E09-05-0364. Epub 2010 Apr 21.

12.

Characterization of the interaction of diacylglycerol acyltransferase-2 with the endoplasmic reticulum and lipid droplets.

McFie PJ, Jin Y, Banman SL, Beauchamp E, Berthiaume LG, Stone SJ.

Biochim Biophys Acta. 2014 Sep;1841(9):1318-28. doi: 10.1016/j.bbalip.2014.06.004. Epub 2014 Jun 19.

PMID:
24953780
13.

Diacylglycerol enrichment of endoplasmic reticulum or lipid droplets recruits perilipin 3/TIP47 during lipid storage and mobilization.

Skinner JR, Shew TM, Schwartz DM, Tzekov A, Lepus CM, Abumrad NA, Wolins NE.

J Biol Chem. 2009 Nov 6;284(45):30941-8. doi: 10.1074/jbc.M109.013995. Epub 2009 Sep 11.

14.

Glycerol-3-phosphate Acyltransferase contributes to triacylglycerol biosynthesis, lipid droplet formation, and host invasion in Metarhizium robertsii.

Gao Q, Shang Y, Huang W, Wang C.

Appl Environ Microbiol. 2013 Dec;79(24):7646-53. doi: 10.1128/AEM.02905-13. Epub 2013 Sep 27.

15.

The role of phospholipids in the biological activity and structure of the endoplasmic reticulum.

Lagace TA, Ridgway ND.

Biochim Biophys Acta. 2013 Nov;1833(11):2499-510. doi: 10.1016/j.bbamcr.2013.05.018. Epub 2013 May 24. Review.

16.

Dictyostelium discoideum Dgat2 can substitute for the essential function of Dgat1 in triglyceride production but not in ether lipid synthesis.

Du X, Herrfurth C, Gottlieb T, Kawelke S, Feussner K, Rühling H, Feussner I, Maniak M.

Eukaryot Cell. 2014 Apr;13(4):517-26. doi: 10.1128/EC.00327-13. Epub 2014 Feb 21.

17.

Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets.

Kuerschner L, Moessinger C, Thiele C.

Traffic. 2008 Mar;9(3):338-52. Epub 2007 Dec 11.

19.

Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation.

Gross DA, Zhan C, Silver DL.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19581-6. doi: 10.1073/pnas.1110817108. Epub 2011 Nov 21.

20.

The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria.

Stone SJ, Levin MC, Zhou P, Han J, Walther TC, Farese RV Jr.

J Biol Chem. 2009 Feb 20;284(8):5352-61. doi: 10.1074/jbc.M805768200. Epub 2008 Dec 1.

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