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Items: 1 to 20 of 160

1.

Cytotoxic agents of the crinane series of amaryllidaceae alkaloids.

Nair JJ, Bastida J, Viladomat F, van Staden J.

Nat Prod Commun. 2012 Dec;7(12):1677-88. Review.

PMID:
23413581
2.

Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.

Nair JJ, Rárová L, Strnad M, Bastida J, van Staden J.

Bioorg Med Chem Lett. 2012 Oct 1;22(19):6195-9. doi: 10.1016/j.bmcl.2012.08.005. Epub 2012 Aug 10.

PMID:
22921081
3.

Alkaloids of the South African Amaryllidaceae: a review.

Nair JJ, Bastida J, Codina C, Viladomat F, van Staden J.

Nat Prod Commun. 2013 Sep;8(9):1335-50. Review.

PMID:
24273880
4.

Mechanistic insights to the cytotoxicity of Amaryllidaceae alkaloids.

Nair JJ, Rárová L, Strnad M, Bastida J, van Staden J.

Nat Prod Commun. 2015 Jan;10(1):171-82. Review.

PMID:
25920242
5.

Cytotoxicity studies of lycorine alkaloids of the Amaryllidaceae.

Nair JJ, van Staden J.

Nat Prod Commun. 2014 Aug;9(8):1193-210. Review.

PMID:
25233606
6.

Lycorine and its derivatives for anticancer drug design.

Lamoral-Theys D, Decaestecker C, Mathieu V, Dubois J, Kornienko A, Kiss R, Evidente A, Pottier L.

Mini Rev Med Chem. 2010 Jan;10(1):41-50. Review.

PMID:
20105122
7.

Apoptosis-Inducing Effects of Amaryllidaceae Alkaloids.

Nair JJ, van Staden J, Bastida J.

Curr Med Chem. 2016;23(2):161-85. Review.

PMID:
26577925
8.

Selective apoptosis-inducing activity of crinum-type Amaryllidaceae alkaloids.

McNulty J, Nair JJ, Codina C, Bastida J, Pandey S, Gerasimoff J, Griffin C.

Phytochemistry. 2007 Apr;68(7):1068-74. Epub 2007 Feb 28.

PMID:
17331551
9.

Acetylcholinesterase inhibition within the lycorine series of Amaryllidaceae alkaloids.

Nair JJ, van Staden J.

Nat Prod Commun. 2012 Jul;7(7):959-62.

PMID:
22908593
10.

Pharmacological and toxicological insights to the South African Amaryllidaceae.

Nair JJ, van Staden J.

Food Chem Toxicol. 2013 Dec;62:262-75. doi: 10.1016/j.fct.2013.08.042. Epub 2013 Aug 28. Review.

PMID:
23994658
11.

Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design.

Evidente A, Kireev AS, Jenkins AR, Romero AE, Steelant WF, Van Slambrouck S, Kornienko A.

Planta Med. 2009 Apr;75(5):501-7. doi: 10.1055/s-0029-1185340. Epub 2009 Feb 23.

12.

Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids.

McNulty J, Nair JJ, Singh M, Crankshaw DJ, Holloway AC, Bastida J.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3233-7. doi: 10.1016/j.bmcl.2009.04.086. Epub 2009 Apr 24.

PMID:
19428250
13.

A formal [3+3]-annulation-based approach to pancratistatins: total synthesis of (±)-7-deoxy-pancratistatin and its 2-epi and 2,4-diepi analogues.

Nieto-García O, Lago-Santomé H, Cagide-Fagín F, Ortiz-Lara JC, Alonso R.

Org Biomol Chem. 2012 Jan 28;10(4):825-34. doi: 10.1039/c1ob06374j. Epub 2011 Dec 1.

PMID:
22130626
14.

Alkaloids from Boophone haemanthoides (Amaryllidaceae).

Nair JJ, Rárová L, Strnad M, Bastidad J, van Staden J.

Nat Prod Commun. 2013 Dec;8(12):1705-10.

PMID:
24555277
15.

Structure-activity studies on the lycorine pharmacophore: A potent inducer of apoptosis in human leukemia cells.

McNulty J, Nair JJ, Bastida J, Pandey S, Griffin C.

Phytochemistry. 2009 May;70(7):913-9. doi: 10.1016/j.phytochem.2009.04.012. Epub 2009 May 20.

PMID:
19464034
16.

Towards a molecular understanding of the biosynthesis of amaryllidaceae alkaloids in support of their expanding medical use.

Takos AM, Rook F.

Int J Mol Sci. 2013 May 31;14(6):11713-41. doi: 10.3390/ijms140611713. Review.

17.

The effect of Amaryllidaceae alkaloids haemanthamine and haemanthidine on cell cycle progression and apoptosis in p53-negative human leukemic Jurkat cells.

Havelek R, Seifrtova M, Kralovec K, Bruckova L, Cahlikova L, Dalecka M, Vavrova J, Rezacova M, Opletal L, Bilkova Z.

Phytomedicine. 2014 Mar 15;21(4):479-90. doi: 10.1016/j.phymed.2013.09.005. Epub 2013 Oct 29.

PMID:
24182986
18.

In vivo Cytotoxicity Studies of Amaryllidaceae Alkaloids.

Nair JJ, Bastida J, van Staden J.

Nat Prod Commun. 2016 Jan;11(1):121-32.

PMID:
26996036
19.

Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.

Van Goietsenoven G, Andolfi A, Lallemand B, Cimmino A, Lamoral-Theys D, Gras T, Abou-Donia A, Dubois J, Lefranc F, Mathieu V, Kornienko A, Kiss R, Evidente A.

J Nat Prod. 2010 Jul 23;73(7):1223-7. doi: 10.1021/np9008255.

PMID:
20550100
20.

Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs.

McNulty J, Nair JJ, Singh M, Crankshaw DJ, Holloway AC.

Bioorg Med Chem Lett. 2010 Apr 1;20(7):2335-9. doi: 10.1016/j.bmcl.2010.01.157. Epub 2010 Feb 4.

PMID:
20189386
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