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Results: 1 to 20 of 89

1.

Cannabisin B induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arrest in HepG2 cells.

Chen T, Hao J, He J, Zhang J, Li Y, Liu R, Li L.

Food Chem. 2013 Jun 1;138(2-3):1034-41. doi: 10.1016/j.foodchem.2012.11.102. Epub 2012 Dec 5.

PMID:
23411211
[PubMed - indexed for MEDLINE]
2.

6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells.

Hung JY, Hsu YL, Li CT, Ko YC, Ni WC, Huang MS, Kuo PL.

J Agric Food Chem. 2009 Oct 28;57(20):9809-16. doi: 10.1021/jf902315e.

PMID:
19799425
[PubMed - indexed for MEDLINE]
3.

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells.

Viola G, Bortolozzi R, Hamel E, Moro S, Brun P, Castagliuolo I, Ferlin MG, Basso G.

Biochem Pharmacol. 2012 Jan 1;83(1):16-26. doi: 10.1016/j.bcp.2011.09.017. Epub 2011 Sep 22.

PMID:
21964343
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells.

Huang WW, Tsai SC, Peng SF, Lin MW, Chiang JH, Chiu YJ, Fushiya S, Tseng MT, Yang JS.

Int J Oncol. 2013 Jun;42(6):2069-77. doi: 10.3892/ijo.2013.1909. Epub 2013 Apr 17.

PMID:
23591552
[PubMed - indexed for MEDLINE]
5.

HBx induces HepG-2 cells autophagy through PI3K/Akt-mTOR pathway.

Wang P, Guo QS, Wang ZW, Qian HX.

Mol Cell Biochem. 2013 Jan;372(1-2):161-8. doi: 10.1007/s11010-012-1457-x. Epub 2012 Sep 23.

PMID:
23001846
[PubMed - indexed for MEDLINE]
6.

Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells.

Tsai SC, Yang JS, Peng SF, Lu CC, Chiang JH, Chung JG, Lin MW, Lin JK, Amagaya S, Wai-Shan Chung C, Tung TT, Huang WW, Tseng MT.

Int J Oncol. 2012 Oct;41(4):1431-42. doi: 10.3892/ijo.2012.1579. Epub 2012 Jul 31.

PMID:
22858649
[PubMed - indexed for MEDLINE]
7.

Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.

Wu JC, Lai CS, Badmaev V, Nagabhushanam K, Ho CT, Pan MH.

Mol Nutr Food Res. 2011 Nov;55(11):1646-54. doi: 10.1002/mnfr.201100454. Epub 2011 Sep 19.

PMID:
21928294
[PubMed - indexed for MEDLINE]
8.

Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells.

Kuo PL, Hsu YL, Cho CY.

Mol Cancer Ther. 2006 Dec;5(12):3209-21.

PMID:
17172425
[PubMed - indexed for MEDLINE]
Free Article
9.

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.

Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.

Carcinogenesis. 2013 Jun;34(6):1331-42. doi: 10.1093/carcin/bgt060. Epub 2013 Feb 7.

PMID:
23393227
[PubMed - indexed for MEDLINE]
Free Article
10.

Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells.

Chow SE, Chen YW, Liang CA, Huang YK, Wang JS.

J Cell Biochem. 2012 Nov;113(11):3476-85. doi: 10.1002/jcb.24224.

PMID:
22689083
[PubMed - indexed for MEDLINE]
11.

Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling.

Wang K, Liu R, Li J, Mao J, Lei Y, Wu J, Zeng J, Zhang T, Wu H, Chen L, Huang C, Wei Y.

Autophagy. 2011 Sep;7(9):966-78. Epub 2011 Sep 1.

PMID:
21610320
[PubMed - indexed for MEDLINE]
Free Article
12.

Fructus ligustri lucidi extracts induce human glioma cell death through regulation of Akt/mTOR pathway in vitro and reduce glioma tumor growth in U87MG xenograft mouse model.

Jeong JC, Kim JW, Kwon CH, Kim TH, Kim YK.

Phytother Res. 2011 Mar;25(3):429-34. doi: 10.1002/ptr.3265. Epub 2010 Aug 25.

PMID:
20737659
[PubMed - indexed for MEDLINE]
13.

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt-TSC2-mTOR signaling.

Liu HL, Zhang YL, Yang N, Zhang YX, Liu XQ, Li CG, Zhao Y, Wang YG, Zhang GG, Yang P, Guo F, Sun Y, Jiang CY.

Cell Death Dis. 2011 May 19;2:e159. doi: 10.1038/cddis.2011.27.

PMID:
21593791
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
[PubMed - indexed for MEDLINE]
Free Article
15.

Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.

Cirstea D, Hideshima T, Rodig S, Santo L, Pozzi S, Vallet S, Ikeda H, Perrone G, Gorgun G, Patel K, Desai N, Sportelli P, Kapoor S, Vali S, Mukherjee S, Munshi NC, Anderson KC, Raje N.

Mol Cancer Ther. 2010 Apr;9(4):963-75. doi: 10.1158/1535-7163.MCT-09-0763. Epub 2010 Apr 6.

PMID:
20371718
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells.

Poornima P, Weng CF, Padma VV.

Food Chem. 2013 Dec 15;141(4):3598-605. doi: 10.1016/j.foodchem.2013.05.138. Epub 2013 Jun 7.

PMID:
23993526
[PubMed - indexed for MEDLINE]
17.

Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling.

Lin JF, Tsai TF, Liao PC, Lin YH, Lin YC, Chen HE, Chou KY, Hwang TI.

Carcinogenesis. 2013 Feb;34(2):406-14. doi: 10.1093/carcin/bgs359. Epub 2012 Nov 21.

PMID:
23172666
[PubMed - indexed for MEDLINE]
Free Article
18.

Inhibition of AMPK-dependent autophagy enhances in vitro antiglioma effect of simvastatin.

Misirkic M, Janjetovic K, Vucicevic L, Tovilovic G, Ristic B, Vilimanovich U, Harhaji-Trajkovic L, Sumarac-Dumanovic M, Micic D, Bumbasirevic V, Trajkovic V.

Pharmacol Res. 2012 Jan;65(1):111-9. doi: 10.1016/j.phrs.2011.08.003. Epub 2011 Aug 18.

PMID:
21871960
[PubMed - indexed for MEDLINE]
19.

Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells.

Yu CC, Chiang PC, Lu PH, Kuo MT, Wen WC, Chen P, Guh JH.

J Nutr Biochem. 2012 Aug;23(8):900-7. doi: 10.1016/j.jnutbio.2011.04.015. Epub 2011 Aug 12.

PMID:
21840189
[PubMed - indexed for MEDLINE]
20.

Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt-mTOR signaling pathway in oral squamous cell carcinoma.

Kapoor V, Zaharieva MM, Das SN, Berger MR.

Cancer Lett. 2012 Jun 1;319(1):39-48. doi: 10.1016/j.canlet.2011.12.032. Epub 2011 Dec 24.

PMID:
22202640
[PubMed - indexed for MEDLINE]

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