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Items: 1 to 20 of 103

1.

6-Hydroxy-[1,1'-biphenyl]-3-yl-cyclohexyl-[11C-carbonyl]carbamate.

Leung K.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2012 Oct 24 [updated 2013 Mar 21].

2.

4-(3-((5-(2-[18F]Fluoroethoxy)pyridine-2-yl)oxy)benzylidene)-N-(pyridazin-3-yl)piperidine-1-carboxamide.

Leung K.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2012 Oct 20 [updated 2013 Feb 07].

3.

Biphenyl-3-yl-4-[11C]methoxyphenylcarbamate.

Leung K.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2012 Dec 18 [updated 2013 Feb 21].

4.

[11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography.

Wilson AA, Garcia A, Parkes J, Houle S, Tong J, Vasdev N.

Nucl Med Biol. 2011 Feb;38(2):247-53. doi: 10.1016/j.nucmedbio.2010.08.001.

PMID:
21315280
5.

PET imaging of fatty acid amide hydrolase in the brain: synthesis and biological evaluation of an 11C-labelled URB597 analogue.

Wyffels L, Muccioli GG, Kapanda CN, Labar G, De Bruyne S, De Vos F, Lambert DM.

Nucl Med Biol. 2010 Jul;37(5):665-75. doi: 10.1016/j.nucmedbio.2010.03.009. Epub 2010 May 6.

PMID:
20610171
6.

The fatty acid amide hydrolase C385A variant affects brain binding of the positron emission tomography tracer [11C]CURB.

Boileau I, Tyndale RF, Williams B, Mansouri E, Westwood DJ, Le Foll B, Rusjan PM, Mizrahi R, De Luca V, Zhou Q, Wilson AA, Houle S, Kish SJ, Tong J.

J Cereb Blood Flow Metab. 2015 Aug;35(8):1237-40. doi: 10.1038/jcbfm.2015.119. Epub 2015 Jun 3.

PMID:
26036940
7.

Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase.

Hicks JW, Parkes J, Sadovski O, Tong J, Houle S, Vasdev N, Wilson AA.

Nucl Med Biol. 2013 Aug;40(6):740-6. doi: 10.1016/j.nucmedbio.2013.04.008. Epub 2013 May 31.

8.

Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo.

Lichtman AH, Hawkins EG, Griffin G, Cravatt BF.

J Pharmacol Exp Ther. 2002 Jul;302(1):73-9.

9.

The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice.

Russo R, Loverme J, La Rana G, Compton TR, Parrott J, Duranti A, Tontini A, Mor M, Tarzia G, Calignano A, Piomelli D.

J Pharmacol Exp Ther. 2007 Jul;322(1):236-42. Epub 2007 Apr 5.

10.

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation.

Fegley D, Gaetani S, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D.

J Pharmacol Exp Ther. 2005 Apr;313(1):352-8. Epub 2004 Dec 3.

12.

Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse.

Justinova Z, Panlilio LV, Moreno-Sanz G, Redhi GH, Auber A, Secci ME, Mascia P, Bandiera T, Armirotti A, Bertorelli R, Chefer SI, Barnes C, Yasar S, Piomelli D, Goldberg SR.

Neuropsychopharmacology. 2015 Aug;40(9):2185-97. doi: 10.1038/npp.2015.62. Epub 2015 Mar 10.

13.

Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on α-Ketoheterocyclic Scaffold.

Wang L, Yui J, Wang Q, Zhang Y, Mori W, Shimoda Y, Fujinaga M, Kumata K, Yamasaki T, Hatori A, Rotstein BH, Collier TL, Ran C, Vasdev N, Zhang MR, Liang SH.

ACS Chem Neurosci. 2016 Jan 20;7(1):109-18. doi: 10.1021/acschemneuro.5b00248. Epub 2015 Nov 17.

14.

PET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates.

Rotstein BH, Wey HY, Shoup TM, Wilson AA, Liang SH, Hooker JM, Vasdev N.

Mol Pharm. 2014 Nov 3;11(11):3832-8. doi: 10.1021/mp500316h. Epub 2014 Jul 16.

15.

The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models.

Caprioli A, Coccurello R, Rapino C, Di Serio S, Di Tommaso M, Vertechy M, Vacca V, Battista N, Pavone F, Maccarrone M, Borsini F.

J Pharmacol Exp Ther. 2012 Jul;342(1):188-95. doi: 10.1124/jpet.111.191403. Epub 2012 Apr 18.

16.

Development of [(11)C]MFTC for PET imaging of fatty acid amide hydrolase in rat and monkey brains.

Kumata K, Yui J, Hatori A, Maeda J, Xie L, Ogawa M, Yamasaki T, Nagai Y, Shimoda Y, Fujinaga M, Kawamura K, Zhang MR.

ACS Chem Neurosci. 2015 Feb 18;6(2):339-46. doi: 10.1021/cn500269g. Epub 2014 Nov 26.

PMID:
25398123
17.

Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain.

Kinsey SG, Long JZ, O'Neal ST, Abdullah RA, Poklis JL, Boger DL, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2009 Sep;330(3):902-10. doi: 10.1124/jpet.109.155465. Epub 2009 Jun 5.

18.

Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus.

Schlosburg JE, Boger DL, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2009 Apr;329(1):314-23. doi: 10.1124/jpet.108.150136. Epub 2009 Jan 23.

19.

Fatty Acid Amide Hydrolase Binding in Brain of Cannabis Users: Imaging With the Novel Radiotracer [11C]CURB.

Boileau I, Mansouri E, Williams B, Le Foll B, Rusjan P, Mizrahi R, Tyndale RF, Huestis MA, Payer DE, Wilson AA, Houle S, Kish SJ, Tong J.

Biol Psychiatry. 2016 Apr 25. pii: S0006-3223(16)32300-9. doi: 10.1016/j.biopsych.2016.04.012. [Epub ahead of print]

PMID:
27345297
20.

The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues.

Clapper JR, Duranti A, Tontini A, Mor M, Tarzia G, Piomelli D.

Pharmacol Res. 2006 Nov;54(5):341-4. Epub 2006 Jun 29.

PMID:
16935521
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