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Results: 1 to 20 of 111

1.

Molecular mechanisms underlying the analgesic property of intrathecal dexmedetomidine and its neurotoxicity evaluation: an in vivo and in vitro experimental study.

Zhang H, Zhou F, Li C, Kong M, Liu H, Zhang P, Zhang S, Cao J, Zhang L, Ma H.

PLoS One. 2013;8(2):e55556. doi: 10.1371/journal.pone.0055556. Epub 2013 Feb 7.

PMID:
23409000
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Biphasic effects of chronic intrathecal gabapentin administration on the expression of protein kinase C gamma in the spinal cord of neuropathic pain rats.

Yeh CY, Chung SC, Tseng FL, Tsai YC, Liu YC.

Acta Anaesthesiol Taiwan. 2011 Dec;49(4):144-8. doi: 10.1016/j.aat.2011.11.006. Epub 2011 Dec 23.

PMID:
22221687
[PubMed - indexed for MEDLINE]
3.

Activation of ERK/CREB pathway in spinal cord contributes to chronic constrictive injury-induced neuropathic pain in rats.

Song XS, Cao JL, Xu YB, He JH, Zhang LC, Zeng YM.

Acta Pharmacol Sin. 2005 Jul;26(7):789-98.

PMID:
15960884
[PubMed - indexed for MEDLINE]
Free Article
4.

Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensory-specific analgesic effects.

Liu H, Zhang HX, Hou HY, Lu XF, Wei JQ, Wang CG, Zhang LC, Zeng YM, Wu YP, Cao JL.

PLoS One. 2011;6(12):e29395. doi: 10.1371/journal.pone.0029395. Epub 2011 Dec 28.

PMID:
22216270
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Intrathecal clonidine in the neonatal rat: dose-dependent analgesia and evaluation of spinal apoptosis and toxicity.

Walker SM, Grafe M, Yaksh TL.

Anesth Analg. 2012 Aug;115(2):450-60. doi: 10.1213/ANE.0b013e3182501a09. Epub 2012 Mar 30.

PMID:
22467896
[PubMed - indexed for MEDLINE]
6.

[Clonidine and dexmedetomidine's effect on the altered expressions of growth associated protein-43 mRNA in rat dorsal root ganglion during the development of chronic neuropathic pain].

Xing YH, Leng YF, Wang SX, Gao XM.

Zhonghua Yi Xue Za Zhi. 2012 Feb 21;92(7):444-7. Chinese.

PMID:
22490962
[PubMed - indexed for MEDLINE]
7.

Effects of radolmidine, a novel alpha2 -adrenergic agonist compared with dexmedetomidine in different pain models in the rat.

Xu M, Kontinen VK, Kalso E.

Anesthesiology. 2000 Aug;93(2):473-81.

PMID:
10910498
[PubMed - indexed for MEDLINE]
Free Article
8.

Antinociceptive effect of intrathecal administration of hypotaurine in rat models of inflammatory and neuropathic pain.

Hara K, Nakamura M, Haranishi Y, Terada T, Kataoka K, Sata T.

Amino Acids. 2012 Jul;43(1):397-404. doi: 10.1007/s00726-011-1094-9. Epub 2011 Oct 5.

PMID:
21971909
[PubMed - indexed for MEDLINE]
9.

Intrathecal adenosine interacts with a spinal noradrenergic system to produce antinociception in nerve-injured rats.

Gomes JA, Li X, Pan HL, Eisenach JC.

Anesthesiology. 1999 Oct;91(4):1072-9.

PMID:
10519511
[PubMed - indexed for MEDLINE]
Free Article
10.

Intrathecal ketorolac tromethamine produces analgesia after chronic constriction injury of sciatic nerve in rat.

Parris WC, Janicki PK, Johnson B Jr, Horn JL.

Can J Anaesth. 1996 Aug;43(8):867-70.

PMID:
8840068
[PubMed - indexed for MEDLINE]
11.

Effect of intrathecal octreotide on thermal hyperalgesia and evoked spinal c-Fos expression in rats with sciatic constriction injury.

Tsai YC, So EC, Chen HH, Wang LK, Chien CH.

Pain. 2002 Oct;99(3):407-13.

PMID:
12406515
[PubMed - indexed for MEDLINE]
12.

Central and peripheral sites of action for CB₂ receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats.

Hsieh GC, Pai M, Chandran P, Hooker BA, Zhu CZ, Salyers AK, Wensink EJ, Zhan C, Carroll WA, Dart MJ, Yao BB, Honore P, Meyer MD.

Br J Pharmacol. 2011 Jan;162(2):428-40. doi: 10.1111/j.1476-5381.2010.01046.x.

PMID:
20880025
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Dexmedetomidine prolongs spinal anaesthesia induced by levobupivacaine 0.5% in guinea-pigs.

Calasans-Maia JA, Zapata-Sudo G, Sudo RT.

J Pharm Pharmacol. 2005 Nov;57(11):1415-20.

PMID:
16259773
[PubMed - indexed for MEDLINE]
14.

Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine.

Nazarian A, Christianson CA, Hua XY, Yaksh TL.

Br J Pharmacol. 2008 Dec;155(7):1117-26. doi: 10.1038/bjp.2008.341. Epub 2008 Sep 1.

PMID:
18846040
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The effects of electroacupuncture on the extracellular signal-regulated kinase 1/2/P2X3 signal pathway in the spinal cord of rats with chronic constriction injury.

Yu J, Zhao C, Luo X.

Anesth Analg. 2013 Jan;116(1):239-46. doi: 10.1213/ANE.0b013e31826f0a4a. Epub 2012 Dec 7.

PMID:
23223107
[PubMed - indexed for MEDLINE]
16.
17.

Chronic intrathecal infusion of gabapentin prevents nerve ligation-induced pain in rats.

Chu LC, Tsaur ML, Lin CS, Hung YC, Wang TY, Chen CC, Cheng JK.

Br J Anaesth. 2011 May;106(5):699-705. doi: 10.1093/bja/aer063. Epub 2011 Mar 25.

PMID:
21441243
[PubMed - indexed for MEDLINE]
Free Article
18.

Intrathecal ultra-low dose naloxone enhances the antinociceptive effect of morphine by enhancing the reuptake of excitatory amino acids from the synaptic cleft in the spinal cord of partial sciatic nerve-transected rats.

Yang CP, Cherng CH, Wu CT, Huang HY, Tao PL, Wong CS.

Anesth Analg. 2011 Dec;113(6):1490-500. doi: 10.1213/ANE.0b013e31822d39c1. Epub 2011 Aug 24.

PMID:
21865493
[PubMed - indexed for MEDLINE]
19.

Effect of intrathecal NG-nitro-L-arginine methyl ester administration on Fos expression in the spinal dorsal horn in rats following sciatic nerve ligation.

Li P, Xue FS, Li CW, Liu KP, Liu Y, Xu YC, Yang QY.

Acta Anaesthesiol Taiwan. 2007 Jun;45(2):65-72.

PMID:
17694681
[PubMed - indexed for MEDLINE]
20.

Antiallodynic effect of intrathecal neostigmine is mediated by spinal nitric oxide in a rat model of diabetic neuropathic pain.

Chen SR, Khan GM, Pan HL.

Anesthesiology. 2001 Oct;95(4):1007-12.

PMID:
11605898
[PubMed - indexed for MEDLINE]
Free Article

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