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Results: 1 to 20 of 114

1.

Monte Carlo simulations based on phase 1 studies predict target attainment of ceftobiprole in nosocomial pneumonia patients: a validation study.

Muller AE, Schmitt-Hoffmann AH, Punt N, Mouton JW.

Antimicrob Agents Chemother. 2013 May;57(5):2047-53. doi: 10.1128/AAC.02292-12. Epub 2013 Feb 12.

PMID:
23403430
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Probability of target attainment for ceftobiprole as derived from a population pharmacokinetic analysis of 150 subjects.

Lodise TP Jr, Pypstra R, Kahn JB, Murthy BP, Kimko HC, Bush K, Noel GJ, Drusano GL.

Antimicrob Agents Chemother. 2007 Jul;51(7):2378-87. Epub 2007 Mar 26.

PMID:
17387149
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identifying exposure targets for treatment of staphylococcal pneumonia with ceftobiprole.

Rodvold KA, Nicolau DP, Lodise TP, Khashab M, Noel GJ, Kahn JB, Gotfried M, Murray SA, Nicholson S, Laohavaleeson S, Tessier PR, Drusano GL.

Antimicrob Agents Chemother. 2009 Aug;53(8):3294-301. doi: 10.1128/AAC.00144-09. Epub 2009 May 18.

PMID:
19451287
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Use of preclinical data for selection of a phase II/III dose for evernimicin and identification of a preclinical MIC breakpoint.

Drusano GL, Preston SL, Hardalo C, Hare R, Banfield C, Andes D, Vesga O, Craig WA.

Antimicrob Agents Chemother. 2001 Jan;45(1):13-22.

PMID:
11120938
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Optimal dose finding of garenoxacin based on population pharmacokinetics/pharmacodynamics and Monte Carlo simulation.

Tanigawara Y, Nozawa K, Tsuda H.

Eur J Clin Pharmacol. 2012 Jan;68(1):39-53. doi: 10.1007/s00228-011-1095-3. Epub 2011 Jul 28.

PMID:
21796376
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Correlation of pharmacokinetic/pharmacodynamic-derived predictions of antibiotic efficacy with clinical outcomes in severely ill patients with Pseudomonas aeruginosa pneumonia.

Fish DN, Kiser TH.

Pharmacotherapy. 2013 Oct;33(10):1022-34. doi: 10.1002/phar.1310. Epub 2013 Jun 6.

PMID:
23744833
[PubMed - indexed for MEDLINE]
8.

Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial.

Sakka SG, Glauner AK, Bulitta JB, Kinzig-Schippers M, Pfister W, Drusano GL, Sörgel F.

Antimicrob Agents Chemother. 2007 Sep;51(9):3304-10. Epub 2007 Jul 9.

PMID:
17620371
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Optimal exposures of ceftazidime predict the probability of microbiological and clinical outcome in the treatment of nosocomial pneumonia.

Muller AE, Punt N, Mouton JW.

J Antimicrob Chemother. 2013 Apr;68(4):900-6. doi: 10.1093/jac/dks468. Epub 2012 Nov 28.

PMID:
23190766
[PubMed - indexed for MEDLINE]
Free Article
10.

Use of population pharmacokinetic modeling and Monte Carlo simulation to describe the pharmacodynamic profile of cefditoren in plasma and epithelial lining fluid.

Lodise TP, Kinzig-Schippers M, Drusano GL, Loos U, Vogel F, Bulitta J, Hinder M, Sörgel F.

Antimicrob Agents Chemother. 2008 Jun;52(6):1945-51. Epub 2007 May 7.

PMID:
17485507
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Comparable population pharmacokinetics and pharmacodynamic breakpoints of cefpirome in cystic fibrosis patients and healthy volunteers.

Bulitta JB, Kinzig M, Landersdorfer CB, Holzgrabe U, Stephan U, Sörgel F.

Antimicrob Agents Chemother. 2011 Jun;55(6):2927-36. doi: 10.1128/AAC.01484-10. Epub 2011 Mar 14.

PMID:
21402834
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Clinical pharmacodynamics of cefepime in patients infected with Pseudomonas aeruginosa.

Crandon JL, Bulik CC, Kuti JL, Nicolau DP.

Antimicrob Agents Chemother. 2010 Mar;54(3):1111-6. doi: 10.1128/AAC.01183-09. Epub 2009 Dec 28.

PMID:
20038614
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Population pharmacokinetic modeling and Monte Carlo simulation of varying doses of intravenous metronidazole.

Sprandel KA, Drusano GL, Hecht DW, Rotschafer JC, Danziger LH, Rodvold KA.

Diagn Microbiol Infect Dis. 2006 Aug;55(4):303-9.

PMID:
16887471
[PubMed - indexed for MEDLINE]
14.

Vancomycin dosing assessment in intensive care unit patients based on a population pharmacokinetic/pharmacodynamic simulation.

Revilla N, Martín-Suárez A, Pérez MP, González FM, Fernández de Gatta Mdel M.

Br J Clin Pharmacol. 2010 Aug;70(2):201-12. doi: 10.1111/j.1365-2125.2010.03679.x.

PMID:
20653673
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Population pharmacokinetics and use of Monte Carlo simulation to evaluate currently recommended dosing regimens of ciprofloxacin in adult patients with cystic fibrosis.

Montgomery MJ, Beringer PM, Aminimanizani A, Louie SG, Shapiro BJ, Jelliffe R, Gill MA.

Antimicrob Agents Chemother. 2001 Dec;45(12):3468-73.

PMID:
11709326
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Monte Carlo simulations: maximizing antibiotic pharmacokinetic data to optimize clinical practice for critically ill patients.

Roberts JA, Kirkpatrick CM, Lipman J.

J Antimicrob Chemother. 2011 Feb;66(2):227-31. doi: 10.1093/jac/dkq449. Epub 2010 Nov 30.

PMID:
21118912
[PubMed - indexed for MEDLINE]
Free Article
17.

Pharmacodynamics of antimicrobials for the empirical treatment of nosocomial pneumonia: a report from the OPTAMA Program.

Sun HK, Kuti JL, Nicolau DP.

Crit Care Med. 2005 Oct;33(10):2222-7.

PMID:
16215374
[PubMed - indexed for MEDLINE]
18.

Cefepime pharmacodynamics in patients with extended spectrum beta-lactamase (ESBL) and non-ESBL infections.

Lee SY, Kuti JL, Nicolau DP.

J Infect. 2007 May;54(5):463-8. Epub 2006 Oct 24.

PMID:
17067681
[PubMed - indexed for MEDLINE]
19.

Pharmacodynamic profiling of ceftobiprole for treatment of complicated skin and skin structure infections.

Kimko H, Xu X, Nandy P, Samtani MN, Strauss RS, Bagchi P, Noel GJ.

Antimicrob Agents Chemother. 2009 Aug;53(8):3371-4. doi: 10.1128/AAC.01653-08. Epub 2009 Jun 15.

PMID:
19528285
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Probability of pharmacodynamic target attainment with standard and prolonged-infusion antibiotic regimens for empiric therapy in adults with hospital-acquired pneumonia.

Kim A, Kuti JL, Nicolau DP.

Clin Ther. 2009 Nov;31(11):2765-78. doi: 10.1016/j.clinthera.2009.11.026.

PMID:
20110018
[PubMed - indexed for MEDLINE]

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