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Results: 1 to 20 of 103

1.

Efficacy and safety of leflunomide in DMARD-naive patients with early rheumatoid arthritis: comparison of a loading and a fixed-dose regimen.

Cutolo M, Bolosiu H, Perdriset G; LEADER Study Group.

Rheumatology (Oxford). 2013 Jun;52(6):1132-40. doi: 10.1093/rheumatology/kes321. Epub 2013 Feb 11.

PMID:
23401601
[PubMed - indexed for MEDLINE]
2.

Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group.

Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N, Furst D, Sharp J, Moreland L, Caldwell J, Kaine J, Strand V.

Arthritis Rheum. 2001 Sep;44(9):1984-92.

PMID:
11592358
[PubMed - indexed for MEDLINE]
Free Article
3.

Combination leflunomide and methotrexate (MTX) therapy for patients with active rheumatoid arthritis failing MTX monotherapy: open-label extension of a randomized, double-blind, placebo controlled trial.

Kremer J, Genovese M, Cannon GW, Caldwell J, Cush J, Furst DE, Luggen M, Keystone E, Bathon J, Kavanaugh A, Ruderman E, Coleman P, Curtis D, Kopp E, Kantor S, Weisman M, Waltuck J, Lindsley HB, Markenson J, Crawford B, Fernando I, Simpson K, Strand V.

J Rheumatol. 2004 Aug;31(8):1521-31.

PMID:
15290730
[PubMed - indexed for MEDLINE]
4.

Infliximab and methotrexate in the treatment of rheumatoid arthritis: a systematic review and meta-analysis of dosage regimens.

Zintzaras E, Dahabreh IJ, Giannouli S, Voulgarelis M, Moutsopoulos HM.

Clin Ther. 2008 Nov;30(11):1939-55. doi: 10.1016/j.clinthera.2008.11.007. Review.

PMID:
19108784
[PubMed - indexed for MEDLINE]
5.

The influence of previous and concomitant leflunomide on the efficacy and safety of infliximab therapy in patients with rheumatoid arthritis; a longitudinal observational study.

Flendrie M, Creemers MC, Welsing PM, van Riel PL.

Rheumatology (Oxford). 2005 Apr;44(4):472-8. Epub 2004 Dec 14.

PMID:
15598707
[PubMed - indexed for MEDLINE]
Free Article
6.

Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid arthritis: results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis).

Furst DE, Schiff MH, Fleischmann RM, Strand V, Birbara CA, Compagnone D, Fischkoff SA, Chartash EK.

J Rheumatol. 2003 Dec;30(12):2563-71.

PMID:
14719195
[PubMed - indexed for MEDLINE]
7.

Efficacy of leflunomide 100mg weekly compared to low dose methotrexate in patients with active rheumatoid arthritis. Double blind, randomized clinical trial.

Jaimes-Hernández J, Meléndez-Mercado CI, Mendoza-Fuentes A, Aranda-Pereira P, Castañeda-Hernández G.

Reumatol Clin. 2012 Sep-Oct;8(5):243-9. Epub 2012 Jul 2.

PMID:
22763150
[PubMed - indexed for MEDLINE]
Free Article
8.

When a DMARD fails, should patients switch to sulfasalazine or add sulfasalazine to continuing leflunomide?

Dougados M, Emery P, Lemmel EM, Zerbini CA, Brin S, van Riel P.

Ann Rheum Dis. 2005 Jan;64(1):44-51. Epub 2004 Jul 22.

PMID:
15271770
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Efficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumor necrosis factor-alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: a pilot study.

Weisman MH, Moreland LW, Furst DE, Weinblatt ME, Keystone EC, Paulus HE, Teoh LS, Velagapudi RB, Noertersheuser PA, Granneman GR, Fischkoff SA, Chartash EK.

Clin Ther. 2003 Jun;25(6):1700-21.

PMID:
12860493
[PubMed - indexed for MEDLINE]
10.

Eight versus 16-week re-evaluation period in rheumatoid arthritis patients treated with leflunomide or methotrexate accompanied by moderate dose prednisone.

Fiehn C, Jacki S, Heilig B, Lampe M, Wiesmüller G, Richter C, Röther E, Rochel E, Gao I.

Rheumatol Int. 2007 Aug;27(10):975-9. Epub 2007 Apr 12.

PMID:
17429636
[PubMed - indexed for MEDLINE]
11.

Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group.

Strand V, Cohen S, Schiff M, Weaver A, Fleischmann R, Cannon G, Fox R, Moreland L, Olsen N, Furst D, Caldwell J, Kaine J, Sharp J, Hurley F, Loew-Friedrich I.

Arch Intern Med. 1999 Nov 22;159(21):2542-50.

PMID:
10573044
[PubMed - indexed for MEDLINE]
12.

The efficacy and safety of leflunomide in patients with active rheumatoid arthritis: a five-year followup study.

Kalden JR, Schattenkirchner M, Sörensen H, Emery P, Deighton C, Rozman B, Breedveld F.

Arthritis Rheum. 2003 Jun;48(6):1513-20.

PMID:
12794818
[PubMed - indexed for MEDLINE]
Free Article
13.

Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: results of a forty-eight–week randomized, double-blind, placebo-controlled, parallel-group phase III trial.

Tak PP, Mease PJ, Genovese MC, Kremer J, Haraoui B, Tanaka Y, Bingham CO 3rd, Ashrafzadeh A, Travers H, Safa-Leathers S, Kumar S, Dummer W.

Arthritis Rheum. 2012 Feb;64(2):360-70.

PMID:
22389919
[PubMed - indexed for MEDLINE]
14.

Combination treatment with infliximab and leflunomide in patients with active rheumatoid arthritis: safety and efficacy in an open-label clinical trial.

Kalden JR, Nüsslein HG, Wollenhaupt J, Burmester GR, Krüger K, Antoni C.

Clin Exp Rheumatol. 2008 Sep-Oct;26(5):834-40.

PMID:
19032816
[PubMed - indexed for MEDLINE]
15.

Leflunomide treatment in elderly patients with rheumatoid or psoriatic arthritis: retrospective analysis of safety and adherence to treatment.

Alivernini S, Mazzotta D, Zoli A, Ferraccioli G.

Drugs Aging. 2009;26(5):395-402. doi: 10.2165/00002512-200926050-00003.

PMID:
19552491
[PubMed - indexed for MEDLINE]
16.

Long-term open-label preliminary study of the safety and efficacy of leflunomide in patients with polyarticular-course juvenile rheumatoid arthritis.

Silverman E, Spiegel L, Hawkins D, Petty R, Goldsmith D, Schanberg L, Duffy C, Howard P, Strand V.

Arthritis Rheum. 2005 Feb;52(2):554-62.

PMID:
15693001
[PubMed - indexed for MEDLINE]
Free Article
17.

Combination of cyclosporine and leflunomide versus single therapy in severe rheumatoid arthritis.

Karanikolas G, Charalambopoulos D, Andrianakos A, Antoniades C, Katsilambros N.

J Rheumatol. 2006 Mar;33(3):486-9.

PMID:
16511917
[PubMed - indexed for MEDLINE]
18.

Leflunomide (Arava) is a useful DMARD in Indian (Asian) patients: a clinic-based observational study of 1-year treatment.

Chopra A, Saluja M, Lagu-Joshi V, Sarmukadam S.

Clin Rheumatol. 2008 Aug;27(8):1039-44. doi: 10.1007/s10067-008-0897-x. Epub 2008 May 10.

PMID:
18470473
[PubMed - indexed for MEDLINE]
19.

Effects of double filtration plasmapheresis, leflunomide, and methotrexate on inflammatory changes found through magnetic resonance imaging in early rheumatoid arthritis.

Yu X, Wang L, Xu P, Lu W, Lan G, Ping L, Wang X, Tian J, Liu J.

J Rheumatol. 2012 Jun;39(6):1171-8. doi: 10.3899/jrheum.110978. Epub 2012 Apr 15.

PMID:
22505700
[PubMed - indexed for MEDLINE]
20.

Efficacy and safety of leflunomide 10 mg versus 20 mg once daily in patients with active rheumatoid arthritis: multinational double-blind, randomized trial.

Poór G, Strand V; Leflunomide Multinational Study Group.

Rheumatology (Oxford). 2004 Jun;43(6):744-9. Epub 2004 Mar 16.

PMID:
15026583
[PubMed - indexed for MEDLINE]
Free Article

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