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Results: 1 to 20 of 91

Similar articles for PubMed (Select 23395632)

1.

Amberlite IR-120H catalyzed MCR: design, synthesis and crystal structure analysis of 1,8-dioxodecahydroacridines as potential inhibitors of sirtuins.

Nakhi A, Srinivas PT, Rahman MS, Kishore R, Seerapu GP, Lalith Kumar K, Haldar D, Rao MV, Pal M.

Bioorg Med Chem Lett. 2013 Mar 15;23(6):1828-33. doi: 10.1016/j.bmcl.2013.01.026. Epub 2013 Jan 19.

PMID:
23395632
2.

Construction and functionalization of pyranone ring fused with pyran moiety: design and synthesis of novel pyrano[4,3-b]pyran-5(4H)-ones as potential inhibitors of sirtuins.

Nakhi A, Rahman MS, Archana S, Kishore R, Seerapu GP, Kumar KL, Haldar D, Pal M.

Bioorg Med Chem Lett. 2013 Jul 15;23(14):4195-205. doi: 10.1016/j.bmcl.2013.05.014. Epub 2013 May 15.

PMID:
23743280
3.

Benzimidazoles as new scaffold of sirtuin inhibitors: green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties.

Yoon YK, Ali MA, Wei AC, Shirazi AN, Parang K, Choon TS.

Eur J Med Chem. 2014 Aug 18;83:448-54. doi: 10.1016/j.ejmech.2014.06.060. Epub 2014 Jun 26.

PMID:
24992072
4.

Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins.

McCarthy AR, Pirrie L, Hollick JJ, Ronseaux S, Campbell J, Higgins M, Staples OD, Tran F, Slawin AM, Lain S, Westwood NJ.

Bioorg Med Chem. 2012 Mar 1;20(5):1779-93. doi: 10.1016/j.bmc.2012.01.001. Epub 2012 Jan 12.

PMID:
22304848
5.

Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).

Huber K, Schemies J, Uciechowska U, Wagner JM, Rumpf T, Lewrick F, Süss R, Sippl W, Jung M, Bracher F.

J Med Chem. 2010 Feb 11;53(3):1383-6. doi: 10.1021/jm901055u.

PMID:
20030343
6.

Inhibitors of Sir2: evaluation of splitomicin analogues.

Posakony J, Hirao M, Stevens S, Simon JA, Bedalov A.

J Med Chem. 2004 May 6;47(10):2635-44.

PMID:
15115404
7.

Catalysis by molecular iodine: a rapid synthesis of 1,8-dioxo-octahydroxanthenes and their evaluation as potential anticancer agents.

Mulakayala N, Murthy PV, Rambabu D, Aeluri M, Adepu R, Krishna GR, Reddy CM, Prasad KR, Chaitanya M, Kumar CS, Rao MV, Pal M.

Bioorg Med Chem Lett. 2012 Mar 15;22(6):2186-91. doi: 10.1016/j.bmcl.2012.01.126. Epub 2012 Feb 7.

PMID:
22365759
8.

Structure and chemistry of the Sir2 family of NAD+-dependent histone/protein deactylases.

Marmorstein R.

Biochem Soc Trans. 2004 Dec;32(Pt 6):904-9. Review.

PMID:
15506920
9.

Sirtuin modulators.

Mahajan SS, Leko V, Simon JA, Bedalov A.

Handb Exp Pharmacol. 2011;206:241-55. doi: 10.1007/978-3-642-21631-2_11. Review.

10.

Structure and autoregulation of the yeast Hst2 homolog of Sir2.

Zhao K, Chai X, Clements A, Marmorstein R.

Nat Struct Biol. 2003 Oct;10(10):864-71. Epub 2003 Sep 21.

PMID:
14502267
11.
12.

Cu(II) Schiff base as catalyst in the synthesis of 1,8-dioxodecahydroacridine.

Vahdat SM, Mardani HR, Golchoubian H, Khavarpour M, Baghery S, Roshankouhi Z.

Comb Chem High Throughput Screen. 2013 Jan;16(1):2-6.

PMID:
22998593
13.

Pd(II)-catalyzed one-pot, three-step route for the synthesis of unsymmetrical acridines.

Guo HM, Mao RZ, Wang QT, Niu HY, Xie MS, Qu GR.

Org Lett. 2013 Nov 1;15(21):5460-3. doi: 10.1021/ol402596g. Epub 2013 Oct 23.

PMID:
24152129
14.

Structure-activity studies on suramin analogues as inhibitors of NAD+-dependent histone deacetylases (sirtuins).

Trapp J, Meier R, Hongwiset D, Kassack MU, Sippl W, Jung M.

ChemMedChem. 2007 Oct;2(10):1419-31.

PMID:
17628866
15.

Sequential coupling/desilylation-coupling/cyclization in a single pot under Pd/C-Cu catalysis: synthesis of 2-(hetero)aryl indoles.

Rao RM, Reddy UC, Alinakhi, Mulakayala N, Alvala M, Arunasree MK, Poondra RR, Iqbal J, Pal M.

Org Biomol Chem. 2011 May 21;9(10):3808-16. doi: 10.1039/c0ob01161d. Epub 2011 Mar 29.

PMID:
21448470
16.
17.

Ultrasound mediated catalyst free synthesis of 6H-1-benzopyrano[4,3-b]quinolin-6-ones leading to novel quinoline derivatives: their evaluation as potential anti-cancer agents.

Mulakayala N, Rambabu D, Raja MR, M C, Kumar CS, Kalle AM, Rama Krishna G, Malla Reddy C, Basaveswara Rao MV, Pal M.

Bioorg Med Chem. 2012 Jan 15;20(2):759-68. doi: 10.1016/j.bmc.2011.12.001. Epub 2011 Dec 8.

PMID:
22202437
18.

Pd-mediated functionalization of polysubstituted pyrroles: their evaluation as potential inhibitors of PDE4.

Bhaskar Kumar T, Sumanth Ch, Vaishaly S, Srinivasa Rao M, Chandra Sekhar KB, Meda CL, Kandale A, Rambabu D, Rama Krishna G, Malla Reddy C, Shiva Kumar K, Parsa KV, Pal M.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5639-47. doi: 10.1016/j.bmcl.2012.06.100. Epub 2012 Jul 20.

PMID:
22871579
19.

Pd-catalyzed direct C-H bond functionalization of spirocyclic σ1 ligands: generation of a pharmacophore model and analysis of the reverse binding mode by docking into a 3D homology model of the σ1 receptor.

Meyer C, Schepmann D, Yanagisawa S, Yamaguchi J, Dal Col V, Laurini E, Itami K, Pricl S, Wünsch B.

J Med Chem. 2012 Sep 27;55(18):8047-65. Epub 2012 Sep 10.

PMID:
22913577
20.

Concise, convergent syntheses of (±)-trichostatin A utilizing a Pd-catalyzed ketone enolate α-alkenylation reaction.

Cosner CC, Helquist P.

Org Lett. 2011 Jul 15;13(14):3564-7. doi: 10.1021/ol200964m. Epub 2011 Jun 21.

PMID:
21688856
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