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Results: 1 to 20 of 120

1.

Methotrexate pharmacogenetics in rheumatoid arthritis: a status report.

Malik F, Ranganathan P.

Pharmacogenomics. 2013 Feb;14(3):305-14. doi: 10.2217/pgs.12.214. Review.

PMID:
23394392
[PubMed - indexed for MEDLINE]
2.

Association of dihydrofolate reductase (DHFR) -317AA genotype with poor response to methotrexate in patients with rheumatoid arthritis.

Milic V, Jekic B, Lukovic L, Bunjevacki V, Milasin J, Novakovic I, Damnjanovic T, Popovic B, Maksimovic N, Damjanov N, Radunovic G, Pejnovic N, Krajinovic M.

Clin Exp Rheumatol. 2012 Mar-Apr;30(2):178-83. Epub 2012 Apr 13.

PMID:
22324981
[PubMed - indexed for MEDLINE]
3.

A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis.

Wessels JA, van der Kooij SM, le Cessie S, Kievit W, Barerra P, Allaart CF, Huizinga TW, Guchelaar HJ; Pharmacogenetics Collaborative Research Group.

Arthritis Rheum. 2007 Jun;56(6):1765-75.

PMID:
17530705
[PubMed - indexed for MEDLINE]
Free Article
4.

Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients.

Owen SA, Hider SL, Martin P, Bruce IN, Barton A, Thomson W.

Pharmacogenomics J. 2013 Jun;13(3):227-34. doi: 10.1038/tpj.2012.7. Epub 2012 Mar 27.

PMID:
22450926
[PubMed - indexed for MEDLINE]
5.

Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.

Lee YC, Cui J, Costenbader KH, Shadick NA, Weinblatt ME, Karlson EW.

Rheumatology (Oxford). 2009 Jun;48(6):613-7. doi: 10.1093/rheumatology/ken513. Epub 2009 Feb 4.

PMID:
19193698
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis.

Weisman MH, Furst DE, Park GS, Kremer JM, Smith KM, Wallace DJ, Caldwell JR, Dervieux T.

Arthritis Rheum. 2006 Feb;54(2):607-12.

PMID:
16447238
[PubMed - indexed for MEDLINE]
Free Article
7.
8.

ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients.

Takatori R, Takahashi KA, Tokunaga D, Hojo T, Fujioka M, Asano T, Hirata T, Kawahito Y, Satomi Y, Nishino H, Tanaka T, Hirota Y, Kubo T.

Clin Exp Rheumatol. 2006 Sep-Oct;24(5):546-54.

PMID:
17181924
[PubMed - indexed for MEDLINE]
9.

Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.

Plaza-Plaza JC, Aguilera M, Cañadas-Garre M, Chemello C, González-Utrilla A, Faus Dader MJ, Calleja MA.

OMICS. 2012 Nov;16(11):589-95. doi: 10.1089/omi.2011.0142. Epub 2012 Oct 24.

PMID:
23095111
[PubMed - indexed for MEDLINE]
10.

Methotrexate pharmacogenomics in rheumatoid arthritis: introducing false-positive report probability.

Dervieux T.

Rheumatology (Oxford). 2009 Jun;48(6):597-8. doi: 10.1093/rheumatology/kep060. Epub 2009 Apr 9. No abstract available.

PMID:
19359345
[PubMed - indexed for MEDLINE]
Free Article
11.

Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis.

Hinks A, Moncrieffe H, Martin P, Ursu S, Lal S, Kassoumeri L, Weiler T, Glass DN, Thompson SD, Wedderburn LR, Thomson W.

Ann Rheum Dis. 2011 Aug;70(8):1395-400. doi: 10.1136/ard.2010.146191. Epub 2011 Apr 22.

PMID:
21515602
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

Ranganathan P, Culverhouse R, Marsh S, Mody A, Scott-Horton TJ, Brasington R, Joseph A, Reddy V, Eisen S, McLeod HL.

J Rheumatol. 2008 Apr;35(4):572-9. Epub 2008 Mar 15.

PMID:
18381794
[PubMed - indexed for MEDLINE]
13.

Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms.

Warren RB, Smith RL, Campalani E, Eyre S, Smith CH, Barker JN, Worthington J, Griffiths CE.

Br J Dermatol. 2009 Feb;160(2):438-41. doi: 10.1111/j.1365-2133.2008.08898.x. Epub 2008 Oct 25.

PMID:
19016697
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Methotrexate pharmacogenetics in rheumatoid arthritis.

Brinker RR, Ranganathan P.

Clin Exp Rheumatol. 2010 Sep-Oct;28(5 Suppl 61):S33-9. Epub 2010 Oct 28. Review.

PMID:
21044431
[PubMed - indexed for MEDLINE]
15.

Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?

Ghodke Y, Chopra A, Joshi K, Patwardhan B.

Clin Rheumatol. 2008 Jun;27(6):787-9. doi: 10.1007/s10067-008-0852-x. Epub 2008 Feb 15.

PMID:
18274813
[PubMed - indexed for MEDLINE]
16.

[The importance of pharmacogenetic tests in evaluation of the effectiveness of methotrexate treatment in rheumatoid arthritis (part 2)].

Swierkot J, Slęzak R.

Postepy Hig Med Dosw (Online). 2011 Mar 30;65:207-15. Polish.

PMID:
21502697
[PubMed - indexed for MEDLINE]
Free Article
17.

Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis.

Hughes LB, Beasley TM, Patel H, Tiwari HK, Morgan SL, Baggott JE, Saag KG, McNicholl J, Moreland LW, Alarcón GS, Bridges SL Jr.

Ann Rheum Dis. 2006 Sep;65(9):1213-8. Epub 2006 Jan 26.

PMID:
16439441
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Clinical pharmacogenetic model to predict response of MTX monotherapy in patients with established rheumatoid arthritis after DMARD failure.

Fransen J, Kooloos WM, Wessels JA, Huizinga TW, Guchelaar HJ, van Riel PL, Barrera P.

Pharmacogenomics. 2012 Jul;13(9):1087-94. doi: 10.2217/pgs.12.83.

PMID:
22838954
[PubMed - indexed for MEDLINE]
19.

MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms.

Owen SA, Lunt M, Bowes J, Hider SL, Bruce IN, Thomson W, Barton A.

Pharmacogenomics J. 2013 Apr;13(2):137-47. doi: 10.1038/tpj.2011.42. Epub 2011 Sep 20.

PMID:
21931346
[PubMed - indexed for MEDLINE]
20.

Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis?

Ranganathan P, Eisen S, Yokoyama WM, McLeod HL.

Ann Rheum Dis. 2003 Jan;62(1):4-9. Review.

PMID:
12480661
[PubMed - indexed for MEDLINE]
Free PMC Article

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