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Items: 1 to 20 of 86

1.

Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma.

Liu H, Han D, Liu Y, Hou X, Wu J, Li H, Yang J, Shen C, Yang G, Fu C, Li X, Che H, Ai J, Zhao S.

J Neurooncol. 2013 Mar;112(1):39-48. doi: 10.1007/s11060-012-1034-x. Epub 2013 Feb 8.

PMID:
23392846
2.

Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.

Sunayama J, Sato A, Matsuda K, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C.

Neuro Oncol. 2010 Dec;12(12):1205-19. doi: 10.1093/neuonc/noq103. Epub 2010 Sep 22.

3.

Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt.

Kuo SZ, Blair KJ, Rahimy E, Kiang A, Abhold E, Fan JB, Wang-Rodriguez J, Altuna X, Ongkeko WM.

BMC Cancer. 2012 Nov 24;12:556. doi: 10.1186/1471-2407-12-556.

4.

Arsenic trioxide depletes cancer stem-like cells and inhibits repopulation of neurosphere derived from glioblastoma by downregulation of Notch pathway.

Wu J, Ji Z, Liu H, Liu Y, Han D, Shi C, Shi C, Wang C, Yang G, Chen X, Shen C, Li H, Bi Y, Zhang D, Zhao S.

Toxicol Lett. 2013 Jun 20;220(1):61-9. doi: 10.1016/j.toxlet.2013.03.019. Epub 2013 Mar 28.

PMID:
23542114
5.

Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.

Carra E, Barbieri F, Marubbi D, Pattarozzi A, Favoni RE, Florio T, Daga A.

Cell Cycle. 2013 Feb 1;12(3):491-500. doi: 10.4161/cc.23372. Epub 2013 Jan 16.

6.

Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002.

Kunnimalaiyaan M, Ndiaye M, Chen H.

Surgery. 2006 Dec;140(6):1009-14; discussion 1014-5. Epub 2006 Nov 1.

PMID:
17188151
7.

Girdin maintains the stemness of glioblastoma stem cells.

Natsume A, Kato T, Kinjo S, Enomoto A, Toda H, Shimato S, Ohka F, Motomura K, Kondo Y, Miyata T, Takahashi M, Wakabayashi T.

Oncogene. 2012 May 31;31(22):2715-24. doi: 10.1038/onc.2011.466. Epub 2011 Oct 24.

PMID:
22020337
8.

Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.

Yu XD, Wang SY, Chen GA, Hou CM, Zhao M, Hong JA, Nguyen DM, Schrump DS.

Cancer J. 2007 Mar-Apr;13(2):105-13.

PMID:
17476138
11.
12.

LY294002 induces G0/G1 cell cycle arrest and apoptosis of cancer stem-like cells from human osteosarcoma via down-regulation of PI3K activity.

Gong C, Liao H, Wang J, Lin Y, Qi J, Qin L, Tian LQ, Guo FJ.

Asian Pac J Cancer Prev. 2012;13(7):3103-7.

13.

An inhibitor of arachidonate 5-lipoxygenase, Nordy, induces differentiation and inhibits self-renewal of glioma stem-like cells.

Wang B, Yu SC, Jiang JY, Porter GW, Zhao LT, Wang Z, Tan H, Cui YH, Qian C, Ping YF, Bian XW.

Stem Cell Rev. 2011 Jun;7(2):458-70. doi: 10.1007/s12015-010-9175-9.

PMID:
20809257
14.

Src activation regulates anoikis in human colon tumor cell lines.

Windham TC, Parikh NU, Siwak DR, Summy JM, McConkey DJ, Kraker AJ, Gallick GE.

Oncogene. 2002 Nov 7;21(51):7797-807.

15.

Knockdown of cyclin D1 inhibits proliferation, induces apoptosis, and attenuates the invasive capacity of human glioblastoma cells.

Wang J, Wang Q, Cui Y, Liu ZY, Zhao W, Wang CL, Dong Y, Hou L, Hu G, Luo C, Chen J, Lu Y.

J Neurooncol. 2012 Feb;106(3):473-84. doi: 10.1007/s11060-011-0692-4. Epub 2011 Sep 13.

PMID:
21912938
16.

Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells.

Macha MA, Matta A, Chauhan SS, Siu KW, Ralhan R.

PLoS One. 2011 Feb 24;6(2):e14728. doi: 10.1371/journal.pone.0014728.

17.

Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway.

Huang KF, Zhang GD, Huang YQ, Diao Y.

Int Immunopharmacol. 2012 Feb;12(2):334-41. doi: 10.1016/j.intimp.2011.12.004. Epub 2011 Dec 17.

PMID:
22182776
18.

Jolkinolide B induces apoptosis in MDA-MB-231 cells through inhibition of the PI3K/Akt signaling pathway.

Lin Y, Cui H, Xu H, Yue L, Xu H, Jiang L, Liu J.

Oncol Rep. 2012 Jun;27(6):1976-80. doi: 10.3892/or.2012.1717. Epub 2012 Mar 12.

PMID:
22426554
19.

Β-elemene inhibits Hsp90/Raf-1 molecular complex inducing apoptosis of glioblastoma cells.

Zhao YS, Zhu TZ, Chen YW, Yao YQ, Wu CM, Wei ZQ, Wang W, Xu YH.

J Neurooncol. 2012 Apr;107(2):307-14. doi: 10.1007/s11060-011-0770-7. Epub 2011 Dec 11.

PMID:
22160627
20.

Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway.

Cao MR, Li Q, Liu ZL, Liu HH, Wang W, Liao XL, Pan YL, Jiang JW.

Hepatobiliary Pancreat Dis Int. 2011 Dec;10(6):599-604.

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