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Results: 1 to 20 of 97

1.

The kinase domains of obscurin interact with intercellular adhesion proteins.

Hu LY, Kontrogianni-Konstantopoulos A.

FASEB J. 2013 May;27(5):2001-12. doi: 10.1096/fj.12-221317. Epub 2013 Feb 7.

PMID:
23392350
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth.

Borisov AB, Raeker MO, Kontrogianni-Konstantopoulos A, Yang K, Kurnit DM, Bloch RJ, Russell MW.

Biochem Biophys Res Commun. 2003 Oct 24;310(3):910-8.

PMID:
14550291
[PubMed - indexed for MEDLINE]
3.

Obscurins: Goliaths and Davids take over non-muscle tissues.

Ackermann MA, Shriver M, Perry NA, Hu LY, Kontrogianni-Konstantopoulos A.

PLoS One. 2014 Feb 6;9(2):e88162. doi: 10.1371/journal.pone.0088162. eCollection 2014.

PMID:
24516603
[PubMed - in process]
Free PMC Article
4.

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

Bagnato P, Barone V, Giacomello E, Rossi D, Sorrentino V.

J Cell Biol. 2003 Jan 20;160(2):245-53. Epub 2003 Jan 13.

PMID:
12527750
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.

Ford-Speelman DL, Roche JA, Bowman AL, Bloch RJ.

Mol Biol Cell. 2009 Sep;20(17):3905-17. doi: 10.1091/mbc.E08-10-1029. Epub 2009 Jul 15.

PMID:
19605563
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly.

Ackermann MA, Hu LY, Bowman AL, Bloch RJ, Kontrogianni-Konstantopoulos A.

Mol Biol Cell. 2009 Jun;20(12):2963-78. doi: 10.1091/mbc.E08-12-1251. Epub 2009 Apr 29.

PMID:
19403693
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Obscurin: a multitasking muscle giant.

Kontrogianni-Konstantopoulos A, Bloch RJ.

J Muscle Res Cell Motil. 2005;26(6-8):419-26. Review.

PMID:
16625317
[PubMed - indexed for MEDLINE]
8.

Developmental expression and differential cellular localization of obscurin and obscurin-associated kinase in cardiac muscle cells.

Borisov AB, Raeker MO, Russell MW.

J Cell Biochem. 2008 Apr 1;103(5):1621-35. Erratum in: J Cell Biochem. 2008 May 1;104(1):357-8.

PMID:
18041765
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.

Fukuzawa A, Lange S, Holt M, Vihola A, Carmignac V, Ferreiro A, Udd B, Gautel M.

J Cell Sci. 2008 Jun 1;121(Pt 11):1841-51. doi: 10.1242/jcs.028019. Epub 2008 May 13.

PMID:
18477606
[PubMed - indexed for MEDLINE]
Free Article
10.

Essential role of obscurin in cardiac myofibrillogenesis and hypertrophic response: evidence from small interfering RNA-mediated gene silencing.

Borisov AB, Sutter SB, Kontrogianni-Konstantopoulos A, Bloch RJ, Westfall MV, Russell MW.

Histochem Cell Biol. 2006 Mar;125(3):227-38. Epub 2005 Oct 5.

PMID:
16205939
[PubMed - indexed for MEDLINE]
11.

Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly.

Young P, Ehler E, Gautel M.

J Cell Biol. 2001 Jul 9;154(1):123-36.

PMID:
11448995
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dynamics of obscurin localization during differentiation and remodeling of cardiac myocytes: obscurin as an integrator of myofibrillar structure.

Borisov AB, Kontrogianni-Konstantopoulos A, Bloch RJ, Westfall MV, Russell MW.

J Histochem Cytochem. 2004 Sep;52(9):1117-27.

PMID:
15314079
[PubMed - indexed for MEDLINE]
13.

Obscurin regulates the organization of myosin into A bands.

Kontrogianni-Konstantopoulos A, Catino DH, Strong JC, Randall WR, Bloch RJ.

Am J Physiol Cell Physiol. 2004 Jul;287(1):C209-17. Epub 2004 Mar 10.

PMID:
15013951
[PubMed - indexed for MEDLINE]
Free Article
14.

Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.

Sutter SB, Raeker MO, Borisov AB, Russell MW.

Dev Genes Evol. 2004 Jul;214(7):352-9. Epub 2004 Jun 5.

PMID:
15185077
[PubMed - indexed for MEDLINE]
15.

The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9.

Bowman AL, Catino DH, Strong JC, Randall WR, Kontrogianni-Konstantopoulos A, Bloch RJ.

Mol Biol Cell. 2008 Sep;19(9):3782-92. doi: 10.1091/mbc.E08-03-0237. Epub 2008 Jun 25.

PMID:
18579686
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Identification, tissue expression and chromosomal localization of human Obscurin-MLCK, a member of the titin and Dbl families of myosin light chain kinases.

Russell MW, Raeker MO, Korytkowski KA, Sonneman KJ.

Gene. 2002 Jan 9;282(1-2):237-46.

PMID:
11814696
[PubMed - indexed for MEDLINE]
17.

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system.

Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, Witt CC, Labeit D, Gregorio CC, Granzier H, Labeit S.

Circ Res. 2001 Nov 23;89(11):1065-72.

PMID:
11717165
[PubMed - indexed for MEDLINE]
Free Article
18.

Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development.

Raeker MO, Bieniek AN, Ryan AS, Tsai HJ, Zahn KM, Russell MW.

Dev Biol. 2010 Jan 15;337(2):432-43. doi: 10.1016/j.ydbio.2009.11.018. Epub 2009 Nov 26.

PMID:
19931525
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Obscurin is required for the lateral alignment of striated myofibrils in zebrafish.

Raeker MO, Su F, Geisler SB, Borisov AB, Kontrogianni-Konstantopoulos A, Lyons SE, Russell MW.

Dev Dyn. 2006 Aug;235(8):2018-29.

PMID:
16779859
[PubMed - indexed for MEDLINE]
Free Article
20.

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.

Cunha SR, Mohler PJ.

J Biol Chem. 2008 Nov 14;283(46):31968-80. doi: 10.1074/jbc.M806050200. Epub 2008 Sep 9.

PMID:
18782775
[PubMed - indexed for MEDLINE]
Free PMC Article

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