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Results: 1 to 20 of 65

1.

Apoptosis therapy: driving cancers down the road to ruin.

Green DR, Walczak H.

Nat Med. 2013 Feb;19(2):131-3. doi: 10.1038/nm.3076. No abstract available.

PMID:
23389605
[PubMed - indexed for MEDLINE]
2.

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.

Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH, Fairbrother WJ, Huang DC, Hymowitz SG, Jin S, Khaw SL, Kovar PJ, Lam LT, Lee J, Maecker HL, Marsh KC, Mason KD, Mitten MJ, Nimmer PM, Oleksijew A, Park CH, Park CM, Phillips DC, Roberts AW, Sampath D, Seymour JF, Smith ML, Sullivan GM, Tahir SK, Tse C, Wendt MD, Xiao Y, Xue JC, Zhang H, Humerickhouse RA, Rosenberg SH, Elmore SW.

Nat Med. 2013 Feb;19(2):202-8. doi: 10.1038/nm.3048. Epub 2013 Jan 6.

PMID:
23291630
[PubMed - indexed for MEDLINE]
3.

ABT-199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets.

Vogler M, Dinsdale D, Dyer MJ, Cohen GM.

Br J Haematol. 2013 Oct;163(1):139-42. doi: 10.1111/bjh.12457. Epub 2013 Jul 4. No abstract available.

PMID:
23826785
[PubMed - indexed for MEDLINE]
4.

BCL2-specific inhibitor ABT-199 synergizes strongly with cytarabine against the early immature LOUCY cell line but not more-differentiated T-ALL cell lines.

Anderson NM, Harrold I, Mansour MR, Sanda T, McKeown M, Nagykary N, Bradner JE, Lan Zhang G, Look AT, Feng H.

Leukemia. 2014 May;28(5):1145-8. doi: 10.1038/leu.2013.377. Epub 2013 Dec 17. No abstract available.

PMID:
24342948
[PubMed - indexed for MEDLINE]
5.

Priming BCL-2 to kill: the combination therapy of tamoxifen and ABT-199 in ER+ breast cancer.

Deng J, Letai A.

Breast Cancer Res. 2013;15(5):317.

PMID:
24172207
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family.

Shangary S, Johnson DE.

Leukemia. 2003 Aug;17(8):1470-81. Review.

PMID:
12886234
[PubMed - indexed for MEDLINE]
7.

[Progress in small-molecule inhibitors of Bcl-2 family proteins].

Tang Y, Zhang DY, Wu XM.

Yao Xue Xue Bao. 2008 Jul;43(7):669-77. Review. Chinese.

PMID:
18819468
[PubMed - indexed for MEDLINE]
8.

Targeting mitochondria emerges as therapeutic strategy.

Garber K.

J Natl Cancer Inst. 2005 Dec 21;97(24):1800-1. No abstract available.

PMID:
16368937
[PubMed - indexed for MEDLINE]
Free Article
9.

ABT-737 increases tyrosine kinase inhibitor-induced apoptosis in chronic myeloid leukemia cells through XIAP downregulation and sensitizes CD34(+) CD38(-) population to imatinib.

Airiau K, Mahon FX, Josselin M, Jeanneteau M, Turcq B, Belloc F.

Exp Hematol. 2012 May;40(5):367-78.e2. doi: 10.1016/j.exphem.2012.01.004. Epub 2012 Jan 10.

PMID:
22240609
[PubMed - indexed for MEDLINE]
10.

BH3 mimetic ABT-737 and a proteasome inhibitor synergistically kill melanomas through Noxa-dependent apoptosis.

Miller LA, Goldstein NB, Johannes WU, Walton CH, Fujita M, Norris DA, Shellman YG.

J Invest Dermatol. 2009 Apr;129(4):964-71. doi: 10.1038/jid.2008.327. Epub 2008 Nov 6.

PMID:
18987671
[PubMed - indexed for MEDLINE]
Free Article
11.

Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia.

Kuroda J, Kimura S, Strasser A, Andreeff M, O'Reilly LA, Ashihara E, Kamitsuji Y, Yokota A, Kawata E, Takeuchi M, Tanaka R, Tabe Y, Taniwaki M, Maekawa T.

Cell Death Differ. 2007 Sep;14(9):1667-77. Epub 2007 May 18.

PMID:
17510658
[PubMed - indexed for MEDLINE]
Free Article
12.

Effector mechanisms of norcantharidin-induced mitotic arrest and apoptosis in human hepatoma cells.

Chen YN, Chen JC, Yin SC, Wang GS, Tsauer W, Hsu SF, Hsu SL.

Int J Cancer. 2002 Jul 10;100(2):158-65.

PMID:
12115564
[PubMed - indexed for MEDLINE]
13.

Inhibition of Bcl-2 and Bcl-X enhances chemotherapy sensitivity in hepatoblastoma cells.

Lieber J, Kirchner B, Eicher C, Warmann SW, Seitz G, Fuchs J, Armeanu-Ebinger S.

Pediatr Blood Cancer. 2010 Dec 1;55(6):1089-95. doi: 10.1002/pbc.22740.

PMID:
20680965
[PubMed - indexed for MEDLINE]
14.

Targeting the Bcl-2-regulated apoptosis pathway by BH3 mimetics: a breakthrough in anticancer therapy?

Labi V, Grespi F, Baumgartner F, Villunger A.

Cell Death Differ. 2008 Jun;15(6):977-87. doi: 10.1038/cdd.2008.37. Epub 2008 Mar 28. Review.

PMID:
18369371
[PubMed - indexed for MEDLINE]
Free Article
15.

[Bcl-2 inhibitor ABT-737 enhances the cisplatin-induced apoptosis in breast cancer T47D cells].

Chen ZJ, Zhang B, Pan SH, Zhao HM, Zhang Y, Feng WH, Li YY, Cao XC.

Zhonghua Zhong Liu Za Zhi. 2011 Dec;33(12):891-5. Chinese.

PMID:
22340096
[PubMed - indexed for MEDLINE]
16.

Apoptosis-based therapies for hematologic malignancies.

Reed JC, Pellecchia M.

Blood. 2005 Jul 15;106(2):408-18. Epub 2005 Mar 29. Review.

PMID:
15797997
[PubMed - indexed for MEDLINE]
Free Article
17.

Subversion of the Bcl-2 life/death switch in cancer development and therapy.

Adams JM, Huang DC, Strasser A, Willis S, Chen L, Wei A, van Delft M, Fletcher JI, Puthalakath H, Kuroda J, Michalak EM, Kelly PN, Bouillet P, Villunger A, O'Reilly L, Bath ML, Smith DP, Egle A, Harris AW, Hinds M, Colman P, Cory S.

Cold Spring Harb Symp Quant Biol. 2005;70:469-77.

PMID:
16869785
[PubMed - indexed for MEDLINE]
18.

Emerging targets for hematological malignancies.

Cilloni D, Frassoni F, Saglio G.

Curr Opin Drug Discov Devel. 2010 Sep;13(5):548-58. Review.

PMID:
20812146
[PubMed - indexed for MEDLINE]
19.

Breaking down tumor defenses.

Hockenbery D.

Chem Biol. 2004 Apr;11(4):417-8. Review. No abstract available.

PMID:
15123233
[PubMed - indexed for MEDLINE]
Free Article
20.

[Induction of apoptosis in prostate cancer cell line PC-3 by BBSKE, a novel organoselenium compound, and its effect in vivo].

Shi CJ, Zeng HH, Li HW, Yang FG, Wu XQ, Yu LZ.

Zhonghua Yi Xue Za Zhi. 2003 Nov 25;83(22):1984-8. Chinese.

PMID:
14703435
[PubMed - indexed for MEDLINE]

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