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Results: 1 to 20 of 98

1.

Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex.

Stiegler AL, Grant TD, Luft JR, Calderwood DA, Snell EH, Boggon TJ.

PLoS One. 2013;8(1):e55591. doi: 10.1371/journal.pone.0055591. Epub 2013 Jan 31.

PMID:
23383235
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase.

Chiswell BP, Stiegler AL, Razinia Z, Nalibotski E, Boggon TJ, Calderwood DA.

J Struct Biol. 2010 Apr;170(1):157-63. doi: 10.1016/j.jsb.2009.12.002. Epub 2009 Dec 4.

PMID:
19963065
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Functional analysis of parvin and different modes of IPP-complex assembly at integrin sites during Drosophila development.

Vakaloglou KM, Chountala M, Zervas CG.

J Cell Sci. 2012 Jul 1;125(Pt 13):3221-32. doi: 10.1242/jcs.102384. Epub 2012 Mar 27.

PMID:
22454516
[PubMed - indexed for MEDLINE]
Free Article
4.

Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation.

Stanchi F, Grashoff C, Nguemeni Yonga CF, Grall D, Fässler R, Van Obberghen-Schilling E.

J Cell Sci. 2009 Jun 1;122(Pt 11):1800-11. doi: 10.1242/jcs.044602. Epub 2009 May 12.

PMID:
19435803
[PubMed - indexed for MEDLINE]
Free Article
5.

The structural basis of integrin-linked kinase-PINCH interactions.

Chiswell BP, Zhang R, Murphy JW, Boggon TJ, Calderwood DA.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20677-82. doi: 10.1073/pnas.0811415106. Epub 2008 Dec 12.

PMID:
19074270
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

mda-9/Syntenin protein positively regulates the activation of Akt protein by facilitating integrin-linked kinase adaptor function during adhesion to type I collagen.

Hwangbo C, Park J, Lee JH.

J Biol Chem. 2011 Sep 23;286(38):33601-12. doi: 10.1074/jbc.M110.206789. Epub 2011 Aug 2.

PMID:
21828040
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells.

Tu Y, Li F, Goicoechea S, Wu C.

Mol Cell Biol. 1999 Mar;19(3):2425-34.

PMID:
10022929
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Integrin-linked kinase regulates N-WASp-mediated actin polymerization and tension development in tracheal smooth muscle.

Zhang W, Wu Y, Wu C, Gunst SJ.

J Biol Chem. 2007 Nov 23;282(47):34568-80. Epub 2007 Sep 25.

PMID:
17897939
[PubMed - indexed for MEDLINE]
Free Article
9.

ILK: a pseudokinase with a unique function in the integrin-actin linkage.

Ghatak S, Morgner J, Wickström SA.

Biochem Soc Trans. 2013 Aug;41(4):995-1001. doi: 10.1042/BST20130062. Review.

PMID:
23863169
[PubMed - indexed for MEDLINE]
10.

The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells.

Dougherty GW, Jose C, Gimona M, Cutler ML.

Eur J Cell Biol. 2008 Sep;87(8-9):721-34. doi: 10.1016/j.ejcb.2008.02.011. Epub 2008 Apr 23.

PMID:
18436335
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain.

Velyvis A, Yang Y, Wu C, Qin J.

J Biol Chem. 2001 Feb 16;276(7):4932-9. Epub 2000 Nov 14.

PMID:
11078733
[PubMed - indexed for MEDLINE]
Free Article
12.

The integrin-linked kinase-PINCH-parvin complex supports integrin αIIbβ3 activation.

Honda S, Shirotani-Ikejima H, Tadokoro S, Tomiyama Y, Miyata T.

PLoS One. 2013 Dec 23;8(12):e85498. doi: 10.1371/journal.pone.0085498. eCollection 2013.

PMID:
24376884
[PubMed - in process]
Free PMC Article
13.

A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.

Tu Y, Huang Y, Zhang Y, Hua Y, Wu C.

J Cell Biol. 2001 Apr 30;153(3):585-98.

PMID:
11331308
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Quantitative chemical proteomics profiling differentiates erlotinib from gefitinib in EGFR wild-type non-small cell lung carcinoma cell lines.

Augustin A, Lamerz J, Meistermann H, Golling S, Scheiblich S, Hermann JC, Duchateau-Nguyen G, Tzouros M, Avila DW, Langen H, Essioux L, Klughammer B.

Mol Cancer Ther. 2013 Apr;12(4):520-9. doi: 10.1158/1535-7163.MCT-12-0880. Epub 2013 Jan 31.

PMID:
23371860
[PubMed - indexed for MEDLINE]
Free Article
15.

Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase.

Yang Y, Wang X, Hawkins CA, Chen K, Vaynberg J, Mao X, Tu Y, Zuo X, Wang J, Wang YX, Wu C, Tjandra N, Qin J.

J Biol Chem. 2009 Feb 27;284(9):5836-44. doi: 10.1074/jbc.M805319200. Epub 2008 Dec 30.

PMID:
19117955
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Significance of thymosin β4 and implication of PINCH-1-ILK-α-parvin (PIP) complex in human dilated cardiomyopathy.

Sopko N, Qin Y, Finan A, Dadabayev A, Chigurupati S, Qin J, Penn MS, Gupta S.

PLoS One. 2011;6(5):e20184. doi: 10.1371/journal.pone.0020184. Epub 2011 May 19.

PMID:
21625516
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Parvin-ILK: An intimate relationship.

Vakaloglou K, Zervas C.

Bioarchitecture. 2012 May 1;2(3):91-94.

PMID:
22880148
[PubMed]
Free PMC Article
19.

LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase.

Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, Carolin AS, Speicher DW, Skordalakes E, Huang Q, Dedhar S, Borden KL, Rauscher FJ 3rd.

Cancer Res. 2014 Mar 1;74(5):1390-403. doi: 10.1158/0008-5472.CAN-13-1275.

PMID:
24590809
[PubMed - indexed for MEDLINE]
20.

Formation and phosphorylation of the PINCH-1-integrin linked kinase-alpha-parvin complex are important for regulation of renal glomerular podocyte adhesion, architecture, and survival.

Yang Y, Guo L, Blattner SM, Mundel P, Kretzler M, Wu C.

J Am Soc Nephrol. 2005 Jul;16(7):1966-76. Epub 2005 May 4.

PMID:
15872073
[PubMed - indexed for MEDLINE]
Free Article

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