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Similar articles for PubMed (Select 23376934)


U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.

Jenkins JL, Agrawal AA, Gupta A, Green MR, Kielkopf CL.

Nucleic Acids Res. 2013 Apr 1;41(6):3859-73. doi: 10.1093/nar/gkt046. Epub 2013 Feb 1.


Alternative conformations at the RNA-binding surface of the N-terminal U2AF(65) RNA recognition motif.

Thickman KR, Sickmier EA, Kielkopf CL.

J Mol Biol. 2007 Feb 23;366(3):703-10. Epub 2006 Dec 2.


Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65.

Jenkins JL, Shen H, Green MR, Kielkopf CL.

J Biol Chem. 2008 Nov 28;283(48):33641-9. doi: 10.1074/jbc.M806297200. Epub 2008 Oct 8.


Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.

Sickmier EA, Frato KE, Shen H, Paranawithana SR, Green MR, Kielkopf CL.

Mol Cell. 2006 Jul 7;23(1):49-59.


Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M.

Nature. 2011 Jul 13;475(7356):408-11. doi: 10.1038/nature10171.


Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.

Agrawal AA, McLaughlin KJ, Jenkins JL, Kielkopf CL.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17420-5. doi: 10.1073/pnas.1412743111. Epub 2014 Nov 24.


A Broad range of conformations contribute to the solution ensemble of the essential splicing factor U2AF(65).

Jenkins JL, Laird KM, Kielkopf CL.

Biochemistry. 2012 Jul 3;51(26):5223-5. Epub 2012 Jun 19.


A flexible RNA backbone within the polypyrimidine tract is required for U2AF65 binding and pre-mRNA splicing in vivo.

Chen C, Zhao X, Kierzek R, Yu YT.

Mol Cell Biol. 2010 Sep;30(17):4108-19. doi: 10.1128/MCB.00531-10. Epub 2010 Jul 6.


hnRNP A1 proofreads 3' splice site recognition by U2AF.

Tavanez JP, Madl T, Kooshapur H, Sattler M, Valcárcel J.

Mol Cell. 2012 Feb 10;45(3):314-29. doi: 10.1016/j.molcel.2011.11.033.


In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site.

Pacheco TR, Coelho MB, Desterro JM, Mollet I, Carmo-Fonseca M.

Mol Cell Biol. 2006 Nov;26(21):8183-90. Epub 2006 Aug 28.


A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts.

Sridharan V, Singh R.

Mol Cell Biol. 2007 Oct;27(20):7334-44. Epub 2007 Aug 20.


RNA induces conformational changes in the SF1/U2AF65 splicing factor complex.

Gupta A, Jenkins JL, Kielkopf CL.

J Mol Biol. 2011 Feb 4;405(5):1128-38. doi: 10.1016/j.jmb.2010.11.054. Epub 2010 Dec 10.


Dual function for U2AF(35) in AG-dependent pre-mRNA splicing.

Guth S, Tange TØ, Kellenberger E, Valcárcel J.

Mol Cell Biol. 2001 Nov;21(22):7673-81.


Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.

Zhang Y, Madl T, Bagdiul I, Kern T, Kang HS, Zou P, Mäusbacher N, Sieber SA, Krämer A, Sattler M.

Nucleic Acids Res. 2013 Jan;41(2):1343-54. doi: 10.1093/nar/gks1097. Epub 2012 Nov 21.


Structure of phosphorylated SF1 bound to U2AF⁶⁵ in an essential splicing factor complex.

Wang W, Maucuer A, Gupta A, Manceau V, Thickman KR, Bauer WJ, Kennedy SD, Wedekind JE, Green MR, Kielkopf CL.

Structure. 2013 Feb 5;21(2):197-208. doi: 10.1016/j.str.2012.10.020. Epub 2012 Dec 27.


Signal-regulated Pre-mRNA occupancy by the general splicing factor U2AF.

Tisserant A, König H.

PLoS One. 2008 Jan 9;3(1):e1418. doi: 10.1371/journal.pone.0001418.

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