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Results: 1 to 20 of 111

1.

Adenovirus serotype 5 vectors with Tat-PTD modified hexon and serotype 35 fiber show greatly enhanced transduction capacity of primary cell cultures.

Yu D, Jin C, Ramachandran M, Xu J, Nilsson B, Korsgren O, Le Blanc K, Uhrbom L, Forsberg-Nilsson K, Westermark B, Adamson R, Maitland N, Fan X, Essand M.

PLoS One. 2013;8(1):e54952. doi: 10.1371/journal.pone.0054952. Epub 2013 Jan 25.

PMID:
23372800
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Adenovirus with hexon Tat-protein transduction domain modification exhibits increased therapeutic effect in experimental neuroblastoma and neuroendocrine tumors.

Yu D, Jin C, Leja J, Majdalani N, Nilsson B, Eriksson F, Essand M.

J Virol. 2011 Dec;85(24):13114-23. doi: 10.1128/JVI.05759-11. Epub 2011 Sep 28.

PMID:
21957304
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation.

Schoggins JW, Nociari M, Philpott N, Falck-Pedersen E.

J Virol. 2005 Sep;79(18):11627-37.

PMID:
16140740
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.

Tsuruta Y, Pereboeva L, Glasgow JN, Rein DT, Kawakami Y, Alvarez RD, Rocconi RP, Siegal GP, Dent P, Fisher PB, Curiel DT.

Clin Cancer Res. 2007 May 1;13(9):2777-83.

PMID:
17473211
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein.

Stevenson SC, Rollence M, Marshall-Neff J, McClelland A.

J Virol. 1997 Jun;71(6):4782-90.

PMID:
9151872
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tat conjugation of adenovirus vector broadens tropism and enhances transduction efficiency.

Yoshioka Y, Asavatanabodee R, Eto Y, Watanabe H, Morishige T, Yao X, Kida S, Maeda M, Mukai Y, Mizuguchi H, Kawasaki K, Okada N, Nakagawa S.

Life Sci. 2008 Nov 21;83(21-22):747-55. doi: 10.1016/j.lfs.2008.09.022. Epub 2008 Oct 5.

PMID:
18930744
[PubMed - indexed for MEDLINE]
7.

Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses.

Bruder JT, Semenova E, Chen P, Limbach K, Patterson NB, Stefaniak ME, Konovalova S, Thomas C, Hamilton M, King CR, Richie TL, Doolan DL.

PLoS One. 2012;7(4):e33920. doi: 10.1371/journal.pone.0033920. Epub 2012 Apr 5. Erratum in: PLoS One. 2012;7(5): doi/10.1371/annotation/c110beed-3cac-48db-9039-ba4498d5db50.

PMID:
22496772
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases.

Shayakhmetov DM, Li ZY, Ni S, Lieber A.

Cancer Res. 2002 Feb 15;62(4):1063-8.

PMID:
11861383
[PubMed - indexed for MEDLINE]
Free Article
10.

Adenovirus serotype 35 vector-induced innate immune responses in dendritic cells derived from wild-type and human CD46-transgenic mice: Comparison with a fiber-substituted Ad vector containing fiber proteins of Ad serotype 35.

Sakurai F, Nakashima K, Yamaguchi T, Ichinose T, Kawabata K, Hayakawa T, Mizuguchi H.

J Control Release. 2010 Dec 1;148(2):212-8. doi: 10.1016/j.jconrel.2010.08.025. Epub 2010 Aug 26.

PMID:
20800630
[PubMed - indexed for MEDLINE]
11.

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity.

Roberts DM, Nanda A, Havenga MJ, Abbink P, Lynch DM, Ewald BA, Liu J, Thorner AR, Swanson PE, Gorgone DA, Lifton MA, Lemckert AA, Holterman L, Chen B, Dilraj A, Carville A, Mansfield KG, Goudsmit J, Barouch DH.

Nature. 2006 May 11;441(7090):239-43. Epub 2006 Apr 16.

PMID:
16625206
[PubMed - indexed for MEDLINE]
12.

A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy.

Stoff-Khalili MA, Rivera AA, Glasgow JN, Le LP, Stoff A, Everts M, Tsuruta Y, Kawakami Y, Bauerschmitz GJ, Mathis JM, Pereboeva L, Seigal GP, Dall P, Curiel DT.

Gene Ther. 2005 Dec;12(23):1696-706.

PMID:
16034451
[PubMed - indexed for MEDLINE]
13.

Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy.

Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT.

Mol Cancer Ther. 2010 Sep;9(9):2536-44. doi: 10.1158/1535-7163.MCT-10-0332. Epub 2010 Aug 24.

PMID:
20736345
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.

Rein DT, Breidenbach M, Kirby TO, Han T, Siegal GP, Bauerschmitz GJ, Wang M, Nettelbeck DM, Tsuruta Y, Yamamoto M, Dall P, Hemminki A, Curiel DT.

Clin Cancer Res. 2005 Feb 1;11(3):1327-35.

PMID:
15709205
[PubMed - indexed for MEDLINE]
Free Article
15.

Fiber-modified adenoviruses for targeted gene therapy.

Wu H, Curiel DT.

Methods Mol Biol. 2008;434:113-32. doi: 10.1007/978-1-60327-248-3_8.

PMID:
18470642
[PubMed - indexed for MEDLINE]
16.

Fiber-modified adenovirus vectors containing the TAT peptide derived from HIV-1 in the fiber knob have efficient gene transfer activity.

Kurachi S, Tashiro K, Sakurai F, Sakurai H, Kawabata K, Yayama K, Okamoto H, Nakagawa S, Mizuguchi H.

Gene Ther. 2007 Aug;14(15):1160-5. Epub 2007 May 17.

PMID:
17508008
[PubMed - indexed for MEDLINE]
17.

Protein transduction domains fused to virus receptors improve cellular virus uptake and enhance oncolysis by tumor-specific replicating vectors.

Kühnel F, Schulte B, Wirth T, Woller N, Schäfers S, Zender L, Manns M, Kubicka S.

J Virol. 2004 Dec;78(24):13743-54.

PMID:
15564483
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Characterization of capsid-modified adenovirus vectors containing heterologous peptides in the fiber knob, protein IX, or hexon.

Kurachi S, Koizumi N, Sakurai F, Kawabata K, Sakurai H, Nakagawa S, Hayakawa T, Mizuguchi H.

Gene Ther. 2007 Feb;14(3):266-74. Epub 2006 Sep 28.

PMID:
17006548
[PubMed - indexed for MEDLINE]
19.

Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice.

Smith TA, Idamakanti N, Rollence ML, Marshall-Neff J, Kim J, Mulgrew K, Nemerow GR, Kaleko M, Stevenson SC.

Hum Gene Ther. 2003 May 20;14(8):777-87.

PMID:
12804140
[PubMed - indexed for MEDLINE]
20.

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