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Results: 1 to 20 of 119

1.

Single-stranded nucleic acids promote SAMHD1 complex formation.

Tüngler V, Staroske W, Kind B, Dobrick M, Kretschmer S, Schmidt F, Krug C, Lorenz M, Chara O, Schwille P, Lee-Kirsch MA.

J Mol Med (Berl). 2013 Jun;91(6):759-70. doi: 10.1007/s00109-013-0995-3. Epub 2013 Jan 31.

PMID:
23371319
[PubMed - indexed for MEDLINE]
2.

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations.

Goncalves A, Karayel E, Rice GI, Bennett KL, Crow YJ, Superti-Furga G, Bürckstümmer T.

Hum Mutat. 2012 Jul;33(7):1116-22. doi: 10.1002/humu.22087. Epub 2012 Apr 16.

PMID:
22461318
[PubMed - indexed for MEDLINE]
3.

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

Beloglazova N, Flick R, Tchigvintsev A, Brown G, Popovic A, Nocek B, Yakunin AF.

J Biol Chem. 2013 Mar 22;288(12):8101-10. doi: 10.1074/jbc.M112.431148. Epub 2013 Jan 30.

PMID:
23364794
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

SAMHD1-dependent retroviral control and escape in mice.

Rehwinkel J, Maelfait J, Bridgeman A, Rigby R, Hayward B, Liberatore RA, Bieniasz PD, Towers GJ, Moita LF, Crow YJ, Bonthron DT, Reis e Sousa C.

EMBO J. 2013 Sep 11;32(18):2454-62. doi: 10.1038/emboj.2013.163. Epub 2013 Jul 19.

PMID:
23872947
[PubMed - indexed for MEDLINE]
Free Article
5.

Aicardi-Goutières syndrome and systemic lupus erythematosus (SLE) in a 12-year-old boy with SAMHD1 mutations.

Ramantani G, Häusler M, Niggemann P, Wessling B, Guttmann H, Mull M, Tenbrock K, Lee-Kirsch MA.

J Child Neurol. 2011 Nov;26(11):1425-8. doi: 10.1177/0883073811408310. Epub 2011 Jun 13.

PMID:
21670392
[PubMed - indexed for MEDLINE]
6.

SAMHD1 host restriction factor: a link with innate immune sensing of retrovirus infection.

Sze A, Olagnier D, Lin R, van Grevenynghe J, Hiscott J.

J Mol Biol. 2013 Dec 13;425(24):4981-94. doi: 10.1016/j.jmb.2013.10.022. Epub 2013 Oct 23. Review.

PMID:
24161438
[PubMed - indexed for MEDLINE]
7.

SAMHD1: a novel antiviral factor in intrinsic immunity.

Chen Z, Zhang L, Ying S.

Future Microbiol. 2012 Sep;7(9):1117-26. doi: 10.2217/fmb.12.81. Review.

PMID:
22953710
[PubMed - indexed for MEDLINE]
8.

SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection.

Berger A, Sommer AF, Zwarg J, Hamdorf M, Welzel K, Esly N, Panitz S, Reuter A, Ramos I, Jatiani A, Mulder LC, Fernandez-Sesma A, Rutsch F, Simon V, König R, Flory E.

PLoS Pathog. 2011 Dec;7(12):e1002425. doi: 10.1371/journal.ppat.1002425. Epub 2011 Dec 8.

PMID:
22174685
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.

Powell RD, Holland PJ, Hollis T, Perrino FW.

J Biol Chem. 2011 Dec 23;286(51):43596-600. doi: 10.1074/jbc.C111.317628. Epub 2011 Nov 7.

PMID:
22069334
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

SAMHD1 prevents autoimmunity by maintaining genome stability.

Kretschmer S, Wolf C, König N, Staroske W, Guck J, Häusler M, Luksch H, Nguyen LA, Kim B, Alexopoulou D, Dahl A, Rapp A, Cardoso MC, Shevchenko A, Lee-Kirsch MA.

Ann Rheum Dis. 2014 Jan 29. doi: 10.1136/annrheumdis-2013-204845. [Epub ahead of print]

PMID:
24445253
[PubMed - as supplied by publisher]
Free Article
11.

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study.

Rice GI, Forte GM, Szynkiewicz M, Chase DS, Aeby A, Abdel-Hamid MS, Ackroyd S, Allcock R, Bailey KM, Balottin U, Barnerias C, Bernard G, Bodemer C, Botella MP, Cereda C, Chandler KE, Dabydeen L, Dale RC, De Laet C, De Goede CG, Del Toro M, Effat L, Enamorado NN, Fazzi E, Gener B, Haldre M, Lin JP, Livingston JH, Lourenco CM, Marques W Jr, Oades P, Peterson P, Rasmussen M, Roubertie A, Schmidt JL, Shalev SA, Simon R, Spiegel R, Swoboda KJ, Temtamy SA, Vassallo G, Vilain CN, Vogt J, Wermenbol V, Whitehouse WP, Soler D, Olivieri I, Orcesi S, Aglan MS, Zaki MS, Abdel-Salam GM, Vanderver A, Kisand K, Rozenberg F, Lebon P, Crow YJ.

Lancet Neurol. 2013 Dec;12(12):1159-69. doi: 10.1016/S1474-4422(13)70258-8. Epub 2013 Oct 30.

PMID:
24183309
[PubMed - indexed for MEDLINE]
12.

Expanding the phenotypic spectrum of lupus erythematosus in Aicardi-Goutières syndrome.

Ramantani G, Kohlhase J, Hertzberg C, Innes AM, Engel K, Hunger S, Borozdin W, Mah JK, Ungerath K, Walkenhorst H, Richardt HH, Buckard J, Bevot A, Siegel C, von Stülpnagel C, Ikonomidou C, Thomas K, Proud V, Niemann F, Wieczorek D, Häusler M, Niggemann P, Baltaci V, Conrad K, Lebon P, Lee-Kirsch MA.

Arthritis Rheum. 2010 May;62(5):1469-77. doi: 10.1002/art.27367.

PMID:
20131292
[PubMed - indexed for MEDLINE]
Free Article
13.

[Research progress of the anti-HIV activity of SAMHD1].

Huang J, Qiu C, Zhang XY.

Bing Du Xue Bao. 2012 Jun;28(4):477-81. Review. Chinese.

PMID:
22978176
[PubMed - indexed for MEDLINE]
14.

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

Clifford R, Louis T, Robbe P, Ackroyd S, Burns A, Timbs AT, Wright Colopy G, Dreau H, Sigaux F, Judde JG, Rotger M, Telenti A, Lin YL, Pasero P, Maelfait J, Titsias M, Cohen DR, Henderson SJ, Ross MT, Bentley D, Hillmen P, Pettitt A, Rehwinkel J, Knight SJ, Taylor JC, Crow YJ, Benkirane M, Schuh A.

Blood. 2014 Feb 13;123(7):1021-31. doi: 10.1182/blood-2013-04-490847. Epub 2013 Dec 12.

PMID:
24335234
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A large homozygous deletion in the SAMHD1 gene causes atypical Aicardi-Goutiéres syndrome associated with mtDNA deletions.

Leshinsky-Silver E, Malinger G, Ben-Sira L, Kidron D, Cohen S, Inbar S, Bezaleli T, Levine A, Vinkler C, Lev D, Lerman-Sagie T.

Eur J Hum Genet. 2011 Mar;19(3):287-92. doi: 10.1038/ejhg.2010.213. Epub 2010 Nov 24.

PMID:
21102625
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.

Behrendt R, Schumann T, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, Dittmer U, Kim B, Mueller W, Gramberg T, Roers A.

Cell Rep. 2013 Aug 29;4(4):689-96. doi: 10.1016/j.celrep.2013.07.037. Epub 2013 Aug 22.

PMID:
23972988
[PubMed - indexed for MEDLINE]
Free Article
17.

Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.

Zhao K, Du J, Han X, Goodier JL, Li P, Zhou X, Wei W, Evans SL, Li L, Zhang W, Cheung LE, Wang G, Kazazian HH Jr, Yu XF.

Cell Rep. 2013 Sep 26;4(6):1108-15. doi: 10.1016/j.celrep.2013.08.019. Epub 2013 Sep 12.

PMID:
24035396
[PubMed - indexed for MEDLINE]
Free Article
18.

The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells.

Franzolin E, Pontarin G, Rampazzo C, Miazzi C, Ferraro P, Palumbo E, Reichard P, Bianchi V.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14272-7. doi: 10.1073/pnas.1312033110. Epub 2013 Jul 15.

PMID:
23858451
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cerebral vasculopathy is a common feature in Aicardi-Goutieres syndrome associated with SAMHD1 mutations.

du Moulin M, Nürnberg P, Crow YJ, Rutsch F.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):E232; author reply E233. doi: 10.1073/pnas.1104699108. Epub 2011 Jun 1. No abstract available.

PMID:
21633013
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Aicardi-Goutières syndrome.

Crow YJ.

Handb Clin Neurol. 2013;113:1629-35. doi: 10.1016/B978-0-444-59565-2.00031-9. Review.

PMID:
23622384
[PubMed - indexed for MEDLINE]

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