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1.

Melatonin induces autophagy via an mTOR-dependent pathway and enhances clearance of mutant-TGFBIp.

Choi SI, Kim KS, Oh JY, Jin JY, Lee GH, Kim EK.

J Pineal Res. 2013 May;54(4):361-72. doi: 10.1111/jpi.12039. Epub 2013 Jan 31.

PMID:
23363291
2.

Autophagy is induced by raptor degradation via the ubiquitin/proteasome system in granular corneal dystrophy type 2.

Choi SI, Maeng YS, Kim KS, Kim TI, Kim EK.

Biochem Biophys Res Commun. 2014 Aug 8;450(4):1505-11. doi: 10.1016/j.bbrc.2014.07.035. Epub 2014 Jul 17.

PMID:
25044116
3.

Impaired autophagy and delayed autophagic clearance of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy type 2.

Choi SI, Kim BY, Dadakhujaev S, Oh JY, Kim TI, Kim JY, Kim EK.

Autophagy. 2012 Dec;8(12):1782-97. doi: 10.4161/auto.22067. Epub 2012 Sep 20.

4.

Lysophosphatidic acid activates TGFBIp expression in human corneal fibroblasts through a TGF-β1-dependent pathway.

Jeon ES, Kim JH, Ryu H, Kim EK.

Cell Signal. 2012 Jun;24(6):1241-50. doi: 10.1016/j.cellsig.2012.02.009. Epub 2012 Feb 21.

PMID:
22374302
5.

Inhibition of TGFBIp expression by lithium: implications for TGFBI-linked corneal dystrophy therapy.

Choi SI, Kim BY, Dadakhujaev S, Jester JV, Ryu H, Kim TI, Kim EK.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3293-300. doi: 10.1167/iovs.10-6405.

PMID:
21310903
6.

Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors.

Choi SI, Dadakhujaev S, Ryu H, Im Kim T, Kim EK.

J Pineal Res. 2011 Aug;51(1):94-103. doi: 10.1111/j.1600-079X.2011.00866.x. Epub 2011 Mar 11.

PMID:
21392093
7.

Lysosomal trafficking of TGFBIp via caveolae-mediated endocytosis.

Choi SI, Maeng YS, Kim TI, Lee Y, Kim YS, Kim EK.

PLoS One. 2015 Apr 8;10(4):e0119561. doi: 10.1371/journal.pone.0119561. eCollection 2015.

8.

Disrupted cell cycle arrest and reduced proliferation in corneal fibroblasts from GCD2 patients: a potential role for altered autophagy flux.

Choi SI, Dadakhujaev S, Maeng YS, Ahn SY, Kim TI, Kim EK.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):288-93. doi: 10.1016/j.bbrc.2014.11.073. Epub 2014 Nov 25.

PMID:
25450621
9.

Autophagy activation: a novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target of rapamycin pathway.

Zhang Q, Yang YJ, Wang H, Dong QT, Wang TJ, Qian HY, Xu H.

Stem Cells Dev. 2012 May 20;21(8):1321-32. doi: 10.1089/scd.2011.0684. Epub 2012 Mar 28.

10.

Inhibitory Effect of Tranilast on Transforming Growth Factor-Beta-Induced Protein in Granular Corneal Dystrophy Type 2 Corneal Fibroblasts.

Kim TI, Lee H, Hong HK, Kim KS, Choi SI, Maeng YS, Kim EK.

Cornea. 2015 Aug;34(8):950-8. doi: 10.1097/ICO.0000000000000466.

PMID:
26020822
11.

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, Prica M, Harhaji-Trajkovic L, Kravic-Stevovic T, Bumbasirevic V, Trajkovic V.

Autophagy. 2011 Jan;7(1):40-50. Epub 2011 Jan 1.

PMID:
20980833
12.

Involvement of melatonin in autophagy-mediated mouse hepatoma H22 cell survival.

Liu C, Jia Z, Zhang X, Hou J, Wang L, Hao S, Ruan X, Yu Z, Zheng Y.

Int Immunopharmacol. 2012 Feb;12(2):394-401. doi: 10.1016/j.intimp.2011.12.012. Epub 2012 Jan 2.

PMID:
22222116
13.
14.

Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion.

Choi YJ, Park YJ, Park JY, Jeong HO, Kim DH, Ha YM, Kim JM, Song YM, Heo HS, Yu BP, Chun P, Moon HR, Chung HY.

PLoS One. 2012;7(8):e43418. doi: 10.1371/journal.pone.0043418. Epub 2012 Aug 22. Erratum in: PLoS One. 2013;8(1). doi:10.1371/annotation/e3163ad5-f3d8-4a21-b3e1-f2033a76f9db.

15.

Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells.

Kongsuphol P, Mukda S, Nopparat C, Villarroel A, Govitrapong P.

J Pineal Res. 2009 Mar;46(2):199-206. doi: 10.1111/j.1600-079X.2008.00648.x. Epub 2008 Nov 19.

PMID:
19054297
16.

Hydrogen peroxide induces Beclin 1-independent autophagic cell death by suppressing the mTOR pathway via promoting the ubiquitination and degradation of Rheb in GSH-depleted RAW 264.7 cells.

Seo G, Kim SK, Byun YJ, Oh E, Jeong SW, Chae GT, Lee SB.

Free Radic Res. 2011 Apr;45(4):389-99. doi: 10.3109/10715762.2010.535530. Epub 2010 Nov 10.

PMID:
21067284
17.

Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway.

Yang YH, Chen K, Li B, Chen JW, Zheng XF, Wang YR, Jiang SD, Jiang LS.

Apoptosis. 2013 Nov;18(11):1363-75. doi: 10.1007/s10495-013-0867-x.

PMID:
23743762
18.

Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation.

Pang XL, He G, Liu YB, Wang Y, Zhang B.

World J Gastroenterol. 2013 Mar 21;19(11):1736-48. doi: 10.3748/wjg.v19.i11.1736.

19.

Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cells.

Yun SM, Jung JH, Jeong SJ, Sohn EJ, Kim B, Kim SH.

Phytother Res. 2014 Mar;28(3):458-64. doi: 10.1002/ptr.5015. Epub 2013 Jun 27.

PMID:
23813779
20.

Melatonin-induced autophagy is associated with degradation of MyoD protein in C2C12 myoblast cells.

Kim CH, Kim KH, Yoo YM.

J Pineal Res. 2012 Oct;53(3):289-97. doi: 10.1111/j.1600-079X.2012.00998.x. Epub 2012 May 14.

PMID:
22582971
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