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Results: 1 to 20 of 110

1.

The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid.

Martin ML, Barceló-Coblijn G, de Almeida RF, Noguera-Salvà MA, Terés S, Higuera M, Liebisch G, Schmitz G, Busquets X, Escribá PV.

Biochim Biophys Acta. 2013 May;1828(5):1405-13. doi: 10.1016/j.bbamem.2013.01.013. Epub 2013 Jan 27.

PMID:
23360770
[PubMed - indexed for MEDLINE]
Free Article
2.

The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes.

Piotto S, Trapani A, Bianchino E, Ibarguren M, López DJ, Busquets X, Concilio S.

Biochim Biophys Acta. 2014 Jun;1838(6):1509-17. doi: 10.1016/j.bbamem.2014.01.014. Epub 2014 Jan 24. Review.

PMID:
24463068
[PubMed - indexed for MEDLINE]
3.

Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.

Piotto S, Concilio S, Bianchino E, Iannelli P, López DJ, Terés S, Ibarguren M, Barceló-Coblijn G, Martin ML, Guardiola-Serrano F, Alonso-Sande M, Funari SS, Busquets X, Escribá PV.

Biochim Biophys Acta. 2014 Jun;1838(6):1628-37. doi: 10.1016/j.bbamem.2013.12.023. Epub 2014 Jan 9.

PMID:
24412218
[PubMed - indexed for MEDLINE]
4.

2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.

Terés S, Lladó V, Higuera M, Barceló-Coblijn G, Martin ML, Noguera-Salvà MA, Marcilla-Etxenike A, García-Verdugo JM, Soriano-Navarro M, Saus C, Gómez-Pinedo U, Busquets X, Escribá PV.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8489-94. doi: 10.1073/pnas.1118349109. Epub 2012 May 14.

PMID:
22586083
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell lines.

Marcilla-Etxenike A, Martín ML, Noguera-Salvà MA, García-Verdugo JM, Soriano-Navarro M, Dey I, Escribá PV, Busquets X.

PLoS One. 2012;7(10):e48235. doi: 10.1371/journal.pone.0048235. Epub 2012 Oct 25.

PMID:
23133576
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.

Barceló-Coblijn G, Martin ML, de Almeida RF, Noguera-Salvà MA, Marcilla-Etxenike A, Guardiola-Serrano F, Lüth A, Kleuser B, Halver JE, Escribá PV.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19569-74. doi: 10.1073/pnas.1115484108. Epub 2011 Nov 21.

PMID:
22106271
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Effect of a 2-hydroxylated fatty acid on cholesterol-rich membrane domains.

Prades J, Funari SS, Gomez-Florit M, Vögler O, Barceló F.

Mol Membr Biol. 2012 Dec;29(8):333-43. doi: 10.3109/09687688.2012.705023. Epub 2012 Jul 26.

PMID:
22830943
[PubMed - indexed for MEDLINE]
8.

Dietary cholesterol induces changes in molecular species of hepatic microsomal phosphatidylcholine.

Bernasconi AM, Garda HA, Brenner RR.

Lipids. 2000 Dec;35(12):1335-44.

PMID:
11201995
[PubMed - indexed for MEDLINE]
9.

Effects of 2-hydroxyoleic acid on the structural properties of biological and model plasma membranes.

Prades J, Alemany R, Perona JS, Funari SS, Vögler O, Ruiz-Gutiérrez V, Escribá PV, Barceló F.

Mol Membr Biol. 2008 Jan;25(1):46-57.

PMID:
17852735
[PubMed - indexed for MEDLINE]
10.

Pivotal role of dihydrofolate reductase knockdown in the anticancer activity of 2-hydroxyoleic acid.

Lladó V, Terés S, Higuera M, Alvarez R, Noguera-Salva MA, Halver JE, Escribá PV, Busquets X.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13754-8. doi: 10.1073/pnas.0907300106. Epub 2009 Aug 3.

PMID:
19666584
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Atomistic molecular dynamics simulations of the interactions of oleic and 2-hydroxyoleic acids with phosphatidylcholine bilayers.

Cerezo J, Zúñiga J, Bastida A, Requena A, Cerón-Carrasco JP.

J Phys Chem B. 2011 Oct 13;115(40):11727-38. doi: 10.1021/jp203498x. Epub 2011 Sep 22.

PMID:
21882864
[PubMed - indexed for MEDLINE]
12.

Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells.

Terés S, Lladó V, Higuera M, Barceló-Coblijn G, Martin ML, Noguera-Salvà MA, Marcilla-Etxenike A, García-Verdugo JM, Soriano-Navarro M, Saus C, Gómez-Pinedo U, Busquets X, Escribá PV.

Autophagy. 2012 Oct;8(10):1542-4. doi: 10.4161/auto.21341. Epub 2012 Aug 15.

PMID:
22892762
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma.

Lladó V, López DJ, Ibarguren M, Alonso M, Soriano JB, Escribá PV, Busquets X.

Biochim Biophys Acta. 2014 Jun;1838(6):1619-27. doi: 10.1016/j.bbamem.2014.01.027. Epub 2014 Feb 10. Review.

PMID:
24525074
[PubMed - indexed for MEDLINE]
14.

Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives.

Ibarguren M, López DJ, Encinar JA, González-Ros JM, Busquets X, Escribá PV.

Biochim Biophys Acta. 2013 Nov;1828(11):2553-63. doi: 10.1016/j.bbamem.2013.06.014. Epub 2013 Jun 18.

PMID:
23792066
[PubMed - indexed for MEDLINE]
Free Article
15.

Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells.

Scaglia N, Igal RA.

J Biol Chem. 2005 Jul 8;280(27):25339-49. Epub 2005 Apr 25.

PMID:
15851470
[PubMed - indexed for MEDLINE]
Free Article
16.

Effect of membrane lipid alteration on the growth, phospholipase C activity and G protein of HT-29 tumor cells.

Awad AB, Ntanios FY, Fink CS, Horvath PJ.

Prostaglandins Leukot Essent Fatty Acids. 1996 Nov;55(5):293-302.

PMID:
8981625
[PubMed - indexed for MEDLINE]
17.
18.

The effects of dietary phospholipids enriched with phosphatidylethanolamine on bile and red cell membrane lipids in humans.

Pakula R, Konikoff FM, Rubin M, Ringel Y, Peled Y, Tietz A, Gilat T.

Lipids. 1996 Mar;31(3):295-303.

PMID:
8900459
[PubMed - indexed for MEDLINE]
19.

Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel.

Schlaepfer IR, Hitz CA, Gijón MA, Bergman BC, Eckel RH, Jacobsen BM.

Mol Cell Endocrinol. 2012 Nov 5;363(1-2):111-21. doi: 10.1016/j.mce.2012.08.005. Epub 2012 Aug 16.

PMID:
22922095
[PubMed - indexed for MEDLINE]
20.

Modification of the fatty acid composition of cultured human fibroblasts.

Spector AA, Kiser RE, Denning GM, Koh SW, DeBault LE.

J Lipid Res. 1979 May;20(4):536-47.

PMID:
458270
[PubMed - indexed for MEDLINE]
Free Article

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