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Results: 1 to 20 of 107

1.

The autoimmunity risk variant LYP-W620 cooperates with CSK in the regulation of TCR signaling.

de la Puerta ML, Trinidad AG, Rodríguez Mdel C, de Pereda JM, Sánchez Crespo M, Bayón Y, Alonso A.

PLoS One. 2013;8(1):e54569. doi: 10.1371/journal.pone.0054569. Epub 2013 Jan 24.

PMID:
23359562
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue.

Fiorillo E, Orrú V, Stanford SM, Liu Y, Salek M, Rapini N, Schenone AD, Saccucci P, Delogu LG, Angelini F, Manca Bitti ML, Schmedt C, Chan AC, Acuto O, Bottini N.

J Biol Chem. 2010 Aug 20;285(34):26506-18. doi: 10.1074/jbc.M110.111104. Epub 2010 Jun 9.

PMID:
20538612
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses.

Vang T, Landskron J, Viken MK, Oberprieler N, Torgersen KM, Mustelin T, Tasken K, Tautz L, Rickert RC, Lie BA.

Hum Immunol. 2013 May;74(5):574-85. doi: 10.1016/j.humimm.2012.12.017. Epub 2013 Jan 17.

PMID:
23333624
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

LYP inhibits T-cell activation when dissociated from CSK.

Vang T, Liu WH, Delacroix L, Wu S, Vasile S, Dahl R, Yang L, Musumeci L, Francis D, Landskron J, Tasken K, Tremblay ML, Lie BA, Page R, Mustelin T, Rahmouni S, Rickert RC, Tautz L.

Nat Chem Biol. 2012 Mar 18;8(5):437-46. doi: 10.1038/nchembio.916.

PMID:
22426112
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase.

Cloutier JF, Veillette A.

J Exp Med. 1999 Jan 4;189(1):111-21.

PMID:
9874568
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.

Yu X, Sun JP, He Y, Guo X, Liu S, Zhou B, Hudmon A, Zhang ZY.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19767-72. Epub 2007 Dec 3.

PMID:
18056643
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF.

Wang B, Lemay S, Tsai S, Veillette A.

Mol Cell Biol. 2001 Feb;21(4):1077-88.

PMID:
11158295
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1.

Perez-Villar JJ, Whitney GS, Bowen MA, Hewgill DH, Aruffo AA, Kanner SB.

Mol Cell Biol. 1999 Apr;19(4):2903-12.

PMID:
10082557
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CSK associates with the TCR zeta and epsilon chains via its SH2 domain; a mechanism for turning off TCR signaling.

Catipović B.

Lijec Vjesn. 1996 Nov-Dec;118(11-12):264-71.

PMID:
9172452
[PubMed - indexed for MEDLINE]
11.

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.

Wu DJ, Zhou W, Enouz S, Orrú V, Stanford SM, Maine CJ, Rapini N, Sawatzke K, Engel I, Fiorillo E, Sherman LA, Kronenberg M, Zehn D, Peterson E, Bottini N.

PLoS One. 2014 Feb 3;9(2):e86677. doi: 10.1371/journal.pone.0086677. eCollection 2014.

PMID:
24498279
[PubMed - in process]
Free PMC Article
12.

A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.

Nika K, Tautz L, Arimura Y, Vang T, Williams S, Mustelin T.

J Biol Chem. 2007 Dec 7;282(49):36000-9. Epub 2007 Sep 26.

PMID:
17897955
[PubMed - indexed for MEDLINE]
Free Article
13.

The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation.

Hill RJ, Zozulya S, Lu YL, Ward K, Gishizky M, Jallal B.

Exp Hematol. 2002 Mar;30(3):237-44.

PMID:
11882361
[PubMed - indexed for MEDLINE]
14.

The putative role of the C1858T polymorphism of protein tyrosine phosphatase PTPN22 gene in autoimmunity.

Gianchecchi E, Palombi M, Fierabracci A.

Autoimmun Rev. 2013 May;12(7):717-25. doi: 10.1016/j.autrev.2012.12.003. Epub 2012 Dec 20. Review.

PMID:
23261816
[PubMed - indexed for MEDLINE]
15.
17.

Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes.

Ladner MB, Bottini N, Valdes AM, Noble JA.

Hum Immunol. 2005 Jan;66(1):60-4.

PMID:
15620463
[PubMed - indexed for MEDLINE]
18.

Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp.

Cohen S, Dadi H, Shaoul E, Sharfe N, Roifman CM.

Blood. 1999 Mar 15;93(6):2013-24.

PMID:
10068674
[PubMed - indexed for MEDLINE]
Free Article
19.

Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases.

Stanford SM, Mustelin TM, Bottini N.

Semin Immunopathol. 2010 Jun;32(2):127-36. doi: 10.1007/s00281-010-0201-4. Epub 2010 Mar 4. Review.

PMID:
20204370
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

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