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Results: 1 to 20 of 105

1.

Chemical genetics of acetyl-CoA carboxylases.

Zu X, Zhong J, Luo D, Tan J, Zhang Q, Wu Y, Liu J, Cao R, Wen G, Cao D.

Molecules. 2013 Jan 28;18(2):1704-19. doi: 10.3390/molecules18021704. Review.

PMID:
23358327
[PubMed - indexed for MEDLINE]
Free Article
2.

Targeting acetyl-CoA carboxylases: small molecular inhibitors and their therapeutic potential.

Luo DX, Tong DJ, Rajput S, Wang C, Liao DF, Cao D, Maser E.

Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):168-84. Review.

PMID:
22339356
[PubMed - indexed for MEDLINE]
3.

Structure, function and selective inhibition of bacterial acetyl-coa carboxylase.

Polyak SW, Abell AD, Wilce MC, Zhang L, Booker GW.

Appl Microbiol Biotechnol. 2012 Feb;93(3):983-92. doi: 10.1007/s00253-011-3796-z. Epub 2011 Dec 20. Review.

PMID:
22183085
[PubMed - indexed for MEDLINE]
4.

Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase.

Zhang H, Yang Z, Shen Y, Tong L.

Science. 2003 Mar 28;299(5615):2064-7.

PMID:
12663926
[PubMed - indexed for MEDLINE]
Free Article
5.

Acetyl-coenzyme A carboxylases: versatile targets for drug discovery.

Tong L, Harwood HJ Jr.

J Cell Biochem. 2006 Dec 15;99(6):1476-88. Review.

PMID:
16983687
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Molecular basis for the inhibition of the carboxyltransferase domain of acetyl-coenzyme-A carboxylase by haloxyfop and diclofop.

Zhang H, Tweel B, Tong L.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5910-5. Epub 2004 Apr 12.

PMID:
15079078
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Structure and function of biotin-dependent carboxylases.

Tong L.

Cell Mol Life Sci. 2013 Mar;70(5):863-91. doi: 10.1007/s00018-012-1096-0. Epub 2012 Aug 7. Review.

PMID:
22869039
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Acetyl-CoA carboxylase-a as a novel target for cancer therapy.

Wang C, Rajput S, Watabe K, Liao DF, Cao D.

Front Biosci (Schol Ed). 2010 Jan 1;2:515-26. Review.

PMID:
20036965
[PubMed - indexed for MEDLINE]
9.

Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery.

Tong L.

Cell Mol Life Sci. 2005 Aug;62(16):1784-803. Review.

PMID:
15968460
[PubMed - indexed for MEDLINE]
10.

Biotinoyl domain of human acetyl-CoA carboxylase: Structural insights into the carboxyl transfer mechanism.

Lee CK, Cheong HK, Ryu KS, Lee JI, Lee W, Jeon YH, Cheong C.

Proteins. 2008 Aug;72(2):613-24. doi: 10.1002/prot.21952.

PMID:
18247344
[PubMed - indexed for MEDLINE]
11.

Multi-subunit acetyl-CoA carboxylases.

Cronan JE Jr, Waldrop GL.

Prog Lipid Res. 2002 Sep;41(5):407-35. Review.

PMID:
12121720
[PubMed - indexed for MEDLINE]
12.

A high-throughput screening assay for the carboxyltransferase subunit of acetyl-CoA carboxylase.

Santoro N, Brtva T, Roest SV, Siegel K, Waldrop GL.

Anal Biochem. 2006 Jul 1;354(1):70-7. Epub 2006 May 3.

PMID:
16707089
[PubMed - indexed for MEDLINE]
13.

A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim.

Xiang S, Callaghan MM, Watson KG, Tong L.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20723-7. doi: 10.1073/pnas.0908431106. Epub 2009 Nov 19.

PMID:
19926852
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden.

Yu LP, Kim YS, Tong L.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22072-7. doi: 10.1073/pnas.1012039107. Epub 2010 Dec 6.

PMID:
21135213
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cyclohexanedione herbicides are inhibitors of rat heart acetyl-CoA carboxylase.

Seng TW, Skillman TR, Yang N, Hammond C.

Bioorg Med Chem Lett. 2003 Oct 6;13(19):3237-42.

PMID:
12951100
[PubMed - indexed for MEDLINE]
16.

Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with CP-640186.

Zhang H, Tweel B, Li J, Tong L.

Structure. 2004 Sep;12(9):1683-91.

PMID:
15341732
[PubMed - indexed for MEDLINE]
17.

Overexpression and kinetic characterization of the carboxyltransferase component of acetyl-CoA carboxylase.

Blanchard CZ, Waldrop GL.

J Biol Chem. 1998 Jul 24;273(30):19140-5.

PMID:
9668099
[PubMed - indexed for MEDLINE]
Free Article
18.

Structure-guided inhibitor design for human acetyl-coenzyme A carboxylase by interspecies active site conversion.

Rajamohan F, Marr E, Reyes AR, Landro JA, Anderson MD, Corbett JW, Dirico KJ, Harwood JH, Tu M, Vajdos FF.

J Biol Chem. 2011 Dec 2;286(48):41510-9. doi: 10.1074/jbc.M111.275396. Epub 2011 Sep 27.

PMID:
21953464
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK.

Cho YS, Lee JI, Shin D, Kim HT, Jung HY, Lee TG, Kang LW, Ahn YJ, Cho HS, Heo YS.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):187-92. doi: 10.1016/j.bbrc.2009.11.029. Epub 2009 Nov 10.

PMID:
19900410
[PubMed - indexed for MEDLINE]
20.

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