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Results: 1 to 20 of 105

1.

Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt.

Mohan ML, Jha BK, Gupta MK, Vasudevan NT, Martelli EE, Mosinski JD, Naga Prasad SV.

Sci Signal. 2013 Jan 22;6(259):ra4. doi: 10.1126/scisignal.2003308.

PMID:
23354687
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress.

Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, Liang W, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY.

Circ Res. 2010 Nov 12;107(10):1275-89. doi: 10.1161/CIRCRESAHA.110.229054. Epub 2010 Sep 16.

PMID:
20847309
[PubMed - indexed for MEDLINE]
Free Article
3.

Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling.

McLean BA, Kienesberger PC, Wang W, Masson G, Zhabyeyev P, Dyck JR, Oudit GY.

J Mol Cell Cardiol. 2013 Jan;54:9-18. doi: 10.1016/j.yjmcc.2012.10.015. Epub 2012 Nov 8.

PMID:
23142539
[PubMed - indexed for MEDLINE]
4.

Inhibition of protein phosphatase 2A activity by PI3Kγ regulates β-adrenergic receptor function.

Vasudevan NT, Mohan ML, Gupta MK, Hussain AK, Naga Prasad SV.

Mol Cell. 2011 Mar 18;41(6):636-48. doi: 10.1016/j.molcel.2011.02.025.

PMID:
21419339
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway.

Haubner BJ, Neely GG, Voelkl JG, Damilano F, Kuba K, Imai Y, Komnenovic V, Mayr A, Pachinger O, Hirsch E, Penninger JM, Metzler B.

PLoS One. 2010 Feb 22;5(2):e9350. doi: 10.1371/journal.pone.0009350.

PMID:
20179753
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Involvement of phosphoinositide 3-kinase gamma in angiogenesis and healing of experimental myocardial infarction in mice.

Siragusa M, Katare R, Meloni M, Damilano F, Hirsch E, Emanueli C, Madeddu P.

Circ Res. 2010 Mar 5;106(4):757-68. doi: 10.1161/CIRCRESAHA.109.207449. Epub 2010 Jan 7.

PMID:
20056919
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload.

Matsuda T, Zhai P, Maejima Y, Hong C, Gao S, Tian B, Goto K, Takagi H, Tamamori-Adachi M, Kitajima S, Sadoshima J.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20900-5. doi: 10.1073/pnas.0808315106. Epub 2008 Dec 23.

PMID:
19106302
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

TcR and TcR-CD28 engagement of protein kinase B (PKB/AKT) and glycogen synthase kinase-3 (GSK-3) operates independently of guanine nucleotide exchange factor VAV-1.

Wood JE, Schneider H, Rudd CE.

J Biol Chem. 2006 Oct 27;281(43):32385-94. Epub 2006 Aug 11.

PMID:
16905544
[PubMed - indexed for MEDLINE]
Free Article
9.

Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation.

Chung E, Yeung F, Leinwand LA.

J Appl Physiol (1985). 2012 May;112(9):1564-75. doi: 10.1152/japplphysiol.00027.2012. Epub 2012 Feb 16.

PMID:
22345431
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation.

Li HJ, Yin H, Yao YY, Shen B, Bader M, Chao L, Chao J.

Cardiovasc Res. 2007 Jan 1;73(1):130-42. Epub 2006 Oct 27.

PMID:
17137568
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Glycogen synthase kinase-3beta is involved in the process of myocardial hypertrophy stimulated by insulin-like growth factor-1.

Seimi SK, Seinosuke K, Tsuyoshi S, Tomomi U, Tetsuaki H, Miki K, Ryuji T, Kenji I, Mitsuhiro Y.

Circ J. 2004 Mar;68(3):247-53.

PMID:
14993781
[PubMed - indexed for MEDLINE]
Free Article
12.

Constitutive glycogen synthase kinase-3alpha/beta activity protects against chronic beta-adrenergic remodelling of the heart.

Webb IG, Nishino Y, Clark JE, Murdoch C, Walker SJ, Makowski MR, Botnar RM, Redwood SR, Shah AM, Marber MS.

Cardiovasc Res. 2010 Aug 1;87(3):494-503. doi: 10.1093/cvr/cvq061. Epub 2010 Mar 17.

PMID:
20299330
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure.

Oudit GY, Crackower MA, Eriksson U, Sarao R, Kozieradzki I, Sasaki T, Irie-Sasaki J, Gidrewicz D, Rybin VO, Wada T, Steinberg SF, Backx PH, Penninger JM.

Circulation. 2003 Oct 28;108(17):2147-52. Epub 2003 Sep 8.

PMID:
12963636
[PubMed - indexed for MEDLINE]
Free Article
14.

The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy.

Luckey SW, Walker LA, Smyth T, Mansoori J, Messmer-Kratzsch A, Rosenzweig A, Olson EN, Leinwand LA.

J Mol Cell Cardiol. 2009 May;46(5):739-47. doi: 10.1016/j.yjmcc.2009.02.010. Epub 2009 Feb 21.

PMID:
19233194
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Glycogen synthase kinase-3 is essential for β-arrestin-2 complex formation and lithium-sensitive behaviors in mice.

O'Brien WT, Huang J, Buccafusca R, Garskof J, Valvezan AJ, Berry GT, Klein PS.

J Clin Invest. 2011 Sep;121(9):3756-62. doi: 10.1172/JCI45194. Epub 2011 Aug 8.

PMID:
21821916
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Inhibitory phosphorylation of GSK-3β by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP).

Zhou X, Wang H, Burg MB, Ferraris JD.

Am J Physiol Renal Physiol. 2013 Apr 1;304(7):F908-17. doi: 10.1152/ajprenal.00591.2012. Epub 2013 Jan 16.

PMID:
23324178
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Atorvastatin inhibits GSK-3beta phosphorylation by cardiac hypertrophic stimuli.

Planavila A, Rodríguez-Calvo R, Palomer X, Coll T, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M.

Biochim Biophys Acta. 2008 Jan-Feb;1781(1-2):26-35. Epub 2007 Nov 12.

PMID:
18036354
[PubMed - indexed for MEDLINE]
18.
19.

PI3Kγ kinase activity is required for optimal T-cell activation and differentiation.

Ladygina N, Gottipati S, Ngo K, Castro G, Ma JY, Banie H, Rao TS, Fung-Leung WP.

Eur J Immunol. 2013 Dec;43(12):3183-96. doi: 10.1002/eji.201343812. Epub 2013 Oct 9.

PMID:
24030559
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure.

Damilano F, Franco I, Perrino C, Schaefer K, Azzolino O, Carnevale D, Cifelli G, Carullo P, Ragona R, Ghigo A, Perino A, Lembo G, Hirsch E.

Circulation. 2011 Feb 1;123(4):391-9. doi: 10.1161/CIRCULATIONAHA.110.950543. Epub 2011 Jan 17.

PMID:
21242482
[PubMed - indexed for MEDLINE]
Free Article
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