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Items: 1 to 20 of 127

1.

A 60day double-blind, placebo-controlled safety study involving Citrus aurantium (bitter orange) extract.

Kaats GR, Miller H, Preuss HG, Stohs SJ.

Food Chem Toxicol. 2013 May;55:358-62. doi: 10.1016/j.fct.2013.01.013. Epub 2013 Jan 25.

PMID:
23354394
2.
3.

The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrine.

Stohs SJ, Preuss HG, Shara M.

Phytother Res. 2011 Oct;25(10):1421-8. doi: 10.1002/ptr.3490. Epub 2011 Apr 8. Review.

PMID:
21480414
4.
5.

Effect of acute administration of an herbal preparation on blood pressure and heart rate in humans.

Seifert JG, Nelson A, Devonish J, Burke ER, Stohs SJ.

Int J Med Sci. 2011 Mar 2;8(3):192-7.

6.

Cardiovascular Safety of Oral p-Synephrine (Bitter Orange) in Healthy Subjects: A Randomized Placebo-Controlled Cross-over Clinical Trial.

Shara M, Stohs SJ, Mukattash TL.

Phytother Res. 2016 May;30(5):842-7. doi: 10.1002/ptr.5590. Epub 2016 Mar 7.

PMID:
26948284
7.

Blood pressure and heart rate effects following a single dose of bitter orange.

Bui LT, Nguyen DT, Ambrose PJ.

Ann Pharmacother. 2006 Jan;40(1):53-7. Epub 2005 Nov 29.

PMID:
16317106
8.

Absence of QTc-interval-prolonging or hemodynamic effects of a single dose of bitter-orange extract in healthy subjects.

Min B, Cios D, Kluger J, White CM.

Pharmacotherapy. 2005 Dec;25(12):1719-24.

PMID:
16305290
9.

Physiological effects following administration of Citrus aurantium for 28 days in rats.

Hansen DK, George NI, White GE, Pellicore LS, Abdel-Rahman A, Fabricant D; Food and Drug Administration.

Toxicol Appl Pharmacol. 2012 Jun 15;261(3):236-47. doi: 10.1016/j.taap.2012.04.006. Epub 2012 Apr 13.

PMID:
22521485
10.

Effects of Citrus aurantium (bitter orange) fruit extracts and p-synephrine on metabolic fluxes in the rat liver.

Peixoto JS, Comar JF, Moreira CT, Soares AA, de Oliveira AL, Bracht A, Peralta RM.

Molecules. 2012 May 16;17(5):5854-69. doi: 10.3390/molecules17055854.

11.

Mass spectrometric determination of the predominant adrenergic protoalkaloids in bitter orange (Citrus aurantium).

Nelson BC, Putzbach K, Sharpless KE, Sander LC.

J Agric Food Chem. 2007 Nov 28;55(24):9769-75. Epub 2007 Oct 30.

PMID:
17966980
12.

Concentrations of p-synephrine in fruits and leaves of Citrus species (Rutaceae) and the acute toxicity testing of Citrus aurantium extract and p-synephrine.

Arbo MD, Larentis ER, Linck VM, Aboy AL, Pimentel AL, Henriques AT, Dallegrave E, Garcia SC, Leal MB, Limberger RP.

Food Chem Toxicol. 2008 Aug;46(8):2770-5. doi: 10.1016/j.fct.2008.04.037. Epub 2008 May 4.

PMID:
18571300
13.

Hemodynamic effects of ephedra-free weight-loss supplements in humans.

Haller CA, Benowitz NL, Jacob P 3rd.

Am J Med. 2005 Sep;118(9):998-1003.

PMID:
16164886
14.

Developmental toxicity of Citrus aurantium in rats.

Hansen DK, Juliar BE, White GE, Pellicore LS.

Birth Defects Res B Dev Reprod Toxicol. 2011 Jun;92(3):216-23. doi: 10.1002/bdrb.20308. Epub 2011 May 18.

15.

A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects.

Stohs SJ, Preuss HG, Shara M.

Oxid Med Cell Longev. 2011;2011:482973. doi: 10.1155/2011/482973. Epub 2011 Aug 1. Review.

16.

Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium.

Mercader J, Wanecq E, Chen J, Carpéné C.

J Physiol Biochem. 2011 Sep;67(3):443-52. doi: 10.1007/s13105-011-0078-2. Epub 2011 Feb 19.

PMID:
21336650
17.

A rapid liquid chromatography electrospray ionization mass spectrometry(n) method for evaluation of synephrine in Citrus aurantium L. samples.

Mattoli L, Cangi F, Maidecchi A, Ghiara C, Tubaro M, Traldi P.

J Agric Food Chem. 2005 Dec 28;53(26):9860-6.

PMID:
16366666
18.

Response of CEDIA amphetamines assay after a single dose of bitter orange.

Nguyen DT, Bui LT, Ambrose PJ.

Ther Drug Monit. 2006 Apr;28(2):252-4.

PMID:
16628139
19.

Absence of furanocoumarins in Advantra Z® (Citrus aurantium, bitter orange) extracts.

Stohs SJ, Miller H, Romano F.

J Diet Suppl. 2014 Sep;11(3):288-93. doi: 10.3109/19390211.2014.937047. Epub 2014 Jul 15.

PMID:
25026202
20.
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