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Results: 1 to 20 of 112

1.

The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the β(1)-adrenergic receptor to G(s).

Hajjhussein H, Gardner LA, Fujii N, Anderson NM, Bahouth SW.

J Recept Signal Transduct Res. 2013 Apr;33(2):79-88. doi: 10.3109/10799893.2012.759590. Epub 2013 Jan 25.

PMID:
23351074
[PubMed - indexed for MEDLINE]
2.

Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies Lysine324 as a residue involved in imparting the high-affinity binding state of agonists.

Zeitoun O, Santos NM, Gardner LA, White SW, Bahouth SW.

Mol Pharmacol. 2006 Sep;70(3):838-50. Epub 2006 Jun 7.

PMID:
16760361
[PubMed - indexed for MEDLINE]
Free Article
3.

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

Feldman DS, Zamah AM, Pierce KL, Miller WE, Kelly F, Rapacciuolo A, Rockman HA, Koch WJ, Luttrell LM.

J Biol Chem. 2002 Aug 9;277(32):28631-40. Epub 2002 May 29.

PMID:
12036966
[PubMed - indexed for MEDLINE]
Free Article
4.

1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.

Smith KJ, Baillie GS, Hyde EI, Li X, Houslay TM, McCahill A, Dunlop AJ, Bolger GB, Klussmann E, Adams DR, Houslay MD.

Cell Signal. 2007 Dec;19(12):2612-24. Epub 2007 Sep 1.

PMID:
17900862
[PubMed - indexed for MEDLINE]
5.

Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins.

Delos Santos NM, Gardner LA, White SW, Bahouth SW.

J Biol Chem. 2006 May 5;281(18):12896-907. Epub 2006 Feb 24.

PMID:
16500896
[PubMed - indexed for MEDLINE]
Free Article
6.

Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation.

Gehret AU, Hinkle PM.

Biochem J. 2010 May 13;428(2):235-45. doi: 10.1042/BJ20100139.

PMID:
20345371
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.

Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ.

J Biol Chem. 2006 Jan 13;281(2):1261-73. Epub 2005 Nov 9.

PMID:
16280323
[PubMed - indexed for MEDLINE]
Free Article
8.

Role of AKAP79/150 protein in β1-adrenergic receptor trafficking and signaling in mammalian cells.

Li X, Nooh MM, Bahouth SW.

J Biol Chem. 2013 Nov 22;288(47):33797-812. doi: 10.1074/jbc.M113.470559. Epub 2013 Oct 11.

PMID:
24121510
[PubMed - indexed for MEDLINE]
9.

Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells.

Malik RU, Ritt M, DeVree BT, Neubig RR, Sunahara RK, Sivaramakrishnan S.

J Biol Chem. 2013 Jun 14;288(24):17167-78. doi: 10.1074/jbc.M113.464065. Epub 2013 Apr 29.

PMID:
23629648
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Distinct interactions of human beta1- and beta2-adrenoceptors with isoproterenol, epinephrine, norepinephrine, and dopamine.

Weitl N, Seifert R.

J Pharmacol Exp Ther. 2008 Dec;327(3):760-9. doi: 10.1124/jpet.108.143412. Epub 2008 Sep 4.

PMID:
18772317
[PubMed - indexed for MEDLINE]
Free Article
12.

Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation.

Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH.

J Biol Chem. 2006 Mar 17;281(11):7684-92. Epub 2006 Jan 3.

PMID:
16407241
[PubMed - indexed for MEDLINE]
Free Article
13.
14.

Mouse beta 3a- and beta 3b-adrenoceptors expressed in Chinese hamster ovary cells display identical pharmacology but utilize distinct signalling pathways.

Hutchinson DS, Bengtsson T, Evans BA, Summers RJ.

Br J Pharmacol. 2002 Apr;135(8):1903-14.

PMID:
11959793
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95.

Hu LA, Chen W, Premont RT, Cong M, Lefkowitz RJ.

J Biol Chem. 2002 Jan 11;277(2):1607-13. Epub 2001 Nov 7.

PMID:
11700307
[PubMed - indexed for MEDLINE]
Free Article
16.

Structure-function relationships of the alpha1b-adrenergic receptor.

Scheer A, Fanelli F, Diviani D, de Benedetti PG, Cotecchia S.

Eur Urol. 1999;36 Suppl 1:11-6.

PMID:
10393467
[PubMed - indexed for MEDLINE]
17.

Mutation of important amino acid residue of Asp104Lys in human beta(1)-adrenergic receptor triggers functional and constitutive inactivation.

Hossain M, Ahmed M, Bhuiyan MA, Ishiguro M, Nakamura T, Ozaki M, Nagatomo T.

Biol Pharm Bull. 2008 Aug;31(8):1517-22.

PMID:
18670082
[PubMed - indexed for MEDLINE]
Free Article
18.

Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system.

Zamah AM, Delahunty M, Luttrell LM, Lefkowitz RJ.

J Biol Chem. 2002 Aug 23;277(34):31249-56. Epub 2002 Jun 12.

PMID:
12063255
[PubMed - indexed for MEDLINE]
Free Article
19.

Interaction with beta-arrestin determines the difference in internalization behavor between beta1- and beta2-adrenergic receptors.

Shiina T, Kawasaki A, Nagao T, Kurose H.

J Biol Chem. 2000 Sep 15;275(37):29082-90.

PMID:
10862778
[PubMed - indexed for MEDLINE]
Free Article
20.

Duality of G protein-coupled mechanisms for beta-adrenergic activation of NKCC activity in skeletal muscle.

Gosmanov AR, Wong JA, Thomason DB.

Am J Physiol Cell Physiol. 2002 Oct;283(4):C1025-32.

PMID:
12225966
[PubMed - indexed for MEDLINE]
Free Article

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