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Results: 1 to 20 of 93

1.

Th inducing POZ-Kruppel Factor (ThPOK) is a key regulator of the immune response since the early steps of colorectal carcinogenesis.

Mariani F, Sena P, Pedroni M, Benatti P, Manni P, Di Gregorio C, Manenti A, Palumbo C, de Leon MP, Roncucci L.

PLoS One. 2013;8(1):e54488. doi: 10.1371/journal.pone.0054488. Epub 2013 Jan 17.

PMID:
23349906
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

p300-mediated acetylation stabilizes the Th-inducing POK factor.

Zhang M, Zhang J, Rui J, Liu X.

J Immunol. 2010 Oct 1;185(7):3960-9. doi: 10.4049/jimmunol.1001462. Epub 2010 Sep 1.

PMID:
20810990
[PubMed - indexed for MEDLINE]
Free Article
3.

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

He X, Park K, Wang H, He X, Zhang Y, Hua X, Li Y, Kappes DJ.

Immunity. 2008 Mar;28(3):346-58. doi: 10.1016/j.immuni.2008.02.006.

PMID:
18342007
[PubMed - indexed for MEDLINE]
Free Article
4.

Expanding roles for ThPOK in thymic development.

Kappes DJ.

Immunol Rev. 2010 Nov;238(1):182-94. doi: 10.1111/j.1600-065X.2010.00958.x. Review.

PMID:
20969593
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells.

Wang L, Wildt KF, Zhu J, Zhang X, Feigenbaum L, Tessarollo L, Paul WE, Fowlkes BJ, Bosselut R.

Nat Immunol. 2008 Oct;9(10):1122-30. doi: 10.1038/ni.1647. Epub 2008 Sep 7.

PMID:
18776904
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

60-kDa Tat-interactive protein (TIP60) positively regulates Th-inducing POK (ThPOK)-mediated repression of eomesodermin in human CD4+ T cells.

Li Y, Tsun A, Gao Z, Han Z, Gao Y, Li Z, Lin F, Wang Y, Wei G, Yao Z, Li B.

J Biol Chem. 2013 May 31;288(22):15537-46. doi: 10.1074/jbc.M112.430207. Epub 2013 Apr 22.

PMID:
23609452
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The enigma of CD4-lineage specification.

Xiong Y, Bosselut R.

Eur J Immunol. 2011 Mar;41(3):568-74. doi: 10.1002/eji.201041098. Epub 2011 Feb 10. Review.

PMID:
21341258
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

CD4-CD8 lineage differentiation: Thpok-ing into the nucleus.

Wang L, Bosselut R.

J Immunol. 2009 Sep 1;183(5):2903-10. doi: 10.4049/jimmunol.0901041. Review.

PMID:
19696430
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus.

Xiong Y, Castro E, Yagi R, Zhu J, Lesourne R, Love PE, Feigenbaum L, Bosselut R.

Eur J Immunol. 2013 Apr;43(4):918-28. doi: 10.1002/eji.201242944. Epub 2013 Feb 12.

PMID:
23310955
[PubMed - indexed for MEDLINE]
10.

TOX is required for development of the CD4 T cell lineage gene program.

Aliahmad P, Kadavallore A, de la Torre B, Kappes D, Kaye J.

J Immunol. 2011 Dec 1;187(11):5931-40. doi: 10.4049/jimmunol.1101474. Epub 2011 Oct 21.

PMID:
22021617
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

PLZF expression during colorectal cancer development and in normal colorectal mucosa according to body size, as marker of colorectal cancer risk.

Mariani F, Sena P, Magnani G, Mancini S, Palumbo C, Ponz de Leon M, Roncucci L.

ScientificWorldJournal. 2013 Nov 14;2013:630869. doi: 10.1155/2013/630869. eCollection 2013.

PMID:
24348178
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells.

Wang L, Wildt KF, Castro E, Xiong Y, Feigenbaum L, Tessarollo L, Bosselut R.

Immunity. 2008 Dec 19;29(6):876-87. doi: 10.1016/j.immuni.2008.09.019. Epub 2008 Dec 8.

PMID:
19062319
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells.

Grueter B, Petter M, Egawa T, Laule-Kilian K, Aldrian CJ, Wuerch A, Ludwig Y, Fukuyama H, Wardemann H, Waldschuetz R, Möröy T, Taniuchi I, Steimle V, Littman DR, Ehlers M.

J Immunol. 2005 Aug 1;175(3):1694-705. Erratum in: J Immunol. 2005 Nov 1;175(9):6238.

PMID:
16034110
[PubMed - indexed for MEDLINE]
Free Article
14.

The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling.

Luckey MA, Kimura MY, Waickman AT, Feigenbaum L, Singer A, Park JH.

Nat Immunol. 2014 Jul;15(7):638-45. doi: 10.1038/ni.2917. Epub 2014 Jun 1.

PMID:
24880459
[PubMed - indexed for MEDLINE]
15.

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage.

Egawa T, Littman DR.

Nat Immunol. 2008 Oct;9(10):1131-9. doi: 10.1038/ni.1652. Epub 2008 Sep 7.

PMID:
18776905
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The network of transcription factors that underlie the CD4 versus CD8 lineage decision.

Naito T, Taniuchi I.

Int Immunol. 2010 Oct;22(10):791-6. doi: 10.1093/intimm/dxq436. Epub 2010 Aug 22. Review.

PMID:
20732858
[PubMed - indexed for MEDLINE]
Free Article
17.

Antagonistic interplay between ThPOK and Runx in lineage choice of thymocytes.

Egawa T, Taniuchi I.

Blood Cells Mol Dis. 2009 Jul-Aug;43(1):27-9. doi: 10.1016/j.bcmd.2009.03.004. Epub 2009 Apr 16.

PMID:
19375362
[PubMed - indexed for MEDLINE]
18.

Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes.

van Hamburg JP, de Bruijn MJ, Ribeiro de Almeida C, Dingjan GM, Hendriks RW.

Mol Immunol. 2009 Oct;46(16):3251-60. doi: 10.1016/j.molimm.2009.08.004. Epub 2009 Sep 2.

PMID:
19729201
[PubMed - indexed for MEDLINE]
19.

Regulation of Th-POK and Runx3 in T cell development in human thymoma.

Tokunaga T, Hayashi A, Kadota Y, Shiono H, Inoue M, Sawabata N, Okumura M.

Autoimmunity. 2009;42(8):653-60. doi: 10.3109/08916930903120941.

PMID:
19886737
[PubMed - indexed for MEDLINE]
20.

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate.

Muroi S, Naoe Y, Miyamoto C, Akiyama K, Ikawa T, Masuda K, Kawamoto H, Taniuchi I.

Nat Immunol. 2008 Oct;9(10):1113-21. doi: 10.1038/ni.1650. Epub 2008 Sep 7.

PMID:
18776907
[PubMed - indexed for MEDLINE]

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