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Results: 1 to 20 of 144

1.

Stabilization of the skeletal muscle ryanodine receptor ion channel-FKBP12 complex by the 1,4-benzothiazepine derivative S107.

Mei Y, Xu L, Kramer HF, Tomberlin GH, Townsend C, Meissner G.

PLoS One. 2013;8(1):e54208. doi: 10.1371/journal.pone.0054208. Epub 2013 Jan 17.

PMID:
23349825
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201.

Blayney LM, Jones JL, Griffiths J, Lai FA.

Cardiovasc Res. 2010 Jan 1;85(1):68-78. doi: 10.1093/cvr/cvp273. Epub .

PMID:
19661110
[PubMed - indexed for MEDLINE]
Free Article
3.

N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor.

Lee EH, Rho SH, Kwon SJ, Eom SH, Allen PD, Kim do H.

J Biol Chem. 2004 Jun 18;279(25):26481-8. Epub 2004 Mar 19.

PMID:
15033987
[PubMed - indexed for MEDLINE]
Free Article
4.

Effects of S-glutathionylation and S-nitrosylation on calmodulin binding to triads and FKBP12 binding to type 1 calcium release channels.

Aracena P, Tang W, Hamilton SL, Hidalgo C.

Antioxid Redox Signal. 2005 Jul-Aug;7(7-8):870-81.

PMID:
15998242
[PubMed - indexed for MEDLINE]
5.

Designing calcium release channel inhibitors with enhanced electron donor properties: stabilizing the closed state of ryanodine receptor type 1.

Ye Y, Yaeger D, Owen LJ, Escobedo JO, Wang J, Singer JD, Strongin RM, Abramson JJ.

Mol Pharmacol. 2012 Jan;81(1):53-62. doi: 10.1124/mol.111.074740. Epub 2011 Oct 11.

PMID:
21989257
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes.

Avila G, Lee EH, Perez CF, Allen PD, Dirksen RT.

J Biol Chem. 2003 Jun 20;278(25):22600-8. Epub 2003 Apr 17.

PMID:
12704193
[PubMed - indexed for MEDLINE]
Free Article
7.

FKBP12 binding modulates ryanodine receptor channel gating.

Gaburjakova M, Gaburjakova J, Reiken S, Huang F, Marx SO, Rosemblit N, Marks AR.

J Biol Chem. 2001 May 18;276(20):16931-5. Epub 2001 Mar 1.

PMID:
11279144
[PubMed - indexed for MEDLINE]
Free Article
8.

PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure.

Reiken S, Lacampagne A, Zhou H, Kherani A, Lehnart SE, Ward C, Huang F, Gaburjakova M, Gaburjakova J, Rosemblit N, Warren MS, He KL, Yi GH, Wang J, Burkhoff D, Vassort G, Marks AR.

J Cell Biol. 2003 Mar 17;160(6):919-28. Epub 2003 Mar 10.

PMID:
12629052
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

RyR1 exhibits lower gain of CICR activity than RyR3 in the SR: evidence for selective stabilization of RyR1 channel.

Murayama T, Ogawa Y.

Am J Physiol Cell Physiol. 2004 Jul;287(1):C36-45. Epub 2004 Feb 25.

PMID:
14985235
[PubMed - indexed for MEDLINE]
Free Article
10.

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle.

Bellinger AM, Reiken S, Carlson C, Mongillo M, Liu X, Rothman L, Matecki S, Lacampagne A, Marks AR.

Nat Med. 2009 Mar;15(3):325-30. doi: 10.1038/nm.1916. Epub 2009 Feb 8.

PMID:
19198614
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

FK-binding protein is associated with the ryanodine receptor of skeletal muscle in vertebrate animals.

Qi Y, Ogunbunmi EM, Freund EA, Timerman AP, Fleischer S.

J Biol Chem. 1998 Dec 25;273(52):34813-9.

PMID:
9857007
[PubMed - indexed for MEDLINE]
Free Article
12.

FKBP12 modulation of the binding of the skeletal ryanodine receptor onto the II-III loop of the dihydropyridine receptor.

O'Reilly FM, Robert M, Jona I, Szegedi C, Albrieux M, Geib S, De Waard M, Villaz M, Ronjat M.

Biophys J. 2002 Jan;82(1 Pt 1):145-55.

PMID:
11751303
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Differential Ca(2+) sensitivity of skeletal and cardiac muscle ryanodine receptors in the presence of calmodulin.

Fruen BR, Bardy JM, Byrem TM, Strasburg GM, Louis CF.

Am J Physiol Cell Physiol. 2000 Sep;279(3):C724-33.

PMID:
10942723
[PubMed - indexed for MEDLINE]
Free Article
14.

Effects of ivermectin and midecamycin on ryanodine receptors and the Ca2+-ATPase in sarcoplasmic reticulum of rabbit and rat skeletal muscle.

Ahern GP, Junankar PR, Pace SM, Curtis S, Mould JA, Dulhunty AF.

J Physiol. 1999 Jan 15;514 ( Pt 2):313-26.

PMID:
9852316
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure.

Yano M, Kobayashi S, Kohno M, Doi M, Tokuhisa T, Okuda S, Suetsugu M, Hisaoka T, Obayashi M, Ohkusa T, Kohno M, Matsuzaki M.

Circulation. 2003 Jan 28;107(3):477-84.

PMID:
12551874
[PubMed - indexed for MEDLINE]
Free Article
16.

K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association.

Hunt DJ, Jones PP, Wang R, Chen W, Bolstad J, Chen K, Shimoni Y, Chen SR.

Biochem J. 2007 Jun 15;404(3):431-8.

PMID:
17313373
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

Bultynck G, De Smet P, Rossi D, Callewaert G, Missiaen L, Sorrentino V, De Smedt H, Parys JB.

Biochem J. 2001 Mar 1;354(Pt 2):413-22.

PMID:
11171121
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Aldolase potentiates DIDS activation of the ryanodine receptor in rabbit skeletal sarcoplasmic reticulum.

Seo IR, Moh SH, Lee EH, Meissner G, Kim do H.

Biochem J. 2006 Oct 15;399(2):325-33.

PMID:
16817780
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

H(2)O(2) and ethanol act synergistically to gate ryanodine receptor/calcium-release channel.

Oba T, Ishikawa T, Murayama T, Ogawa Y, Yamaguchi M.

Am J Physiol Cell Physiol. 2000 Nov;279(5):C1366-74.

PMID:
11029284
[PubMed - indexed for MEDLINE]
Free Article

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