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Results: 1 to 20 of 96

1.

Interleukins-12 and -23 do not alter expression or activity of multiple cytochrome P450 enzymes in cryopreserved human hepatocytes.

Dallas S, Chattopadhyay S, Sensenhauser C, Batheja A, Singer M, Silva J.

Drug Metab Dispos. 2013 Apr;41(4):689-93. doi: 10.1124/dmd.112.048884. Epub 2013 Jan 24.

PMID:
23349185
[PubMed - indexed for MEDLINE]
Free Article
2.

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes.

Madan A, Graham RA, Carroll KM, Mudra DR, Burton LA, Krueger LA, Downey AD, Czerwinski M, Forster J, Ribadeneira MD, Gan LS, LeCluyse EL, Zech K, Robertson P Jr, Koch P, Antonian L, Wagner G, Yu L, Parkinson A.

Drug Metab Dispos. 2003 Apr;31(4):421-31.

PMID:
12642468
[PubMed - indexed for MEDLINE]
Free Article
3.

Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture.

Muntané-Relat J, Ourlin JC, Domergue J, Maurel P.

Hepatology. 1995 Oct;22(4 Pt 1):1143-53.

PMID:
7557864
[PubMed - indexed for MEDLINE]
4.

Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up.

Meunier V, Bourrié M, Julian B, Marti E, Guillou F, Berger Y, Fabre G.

Xenobiotica. 2000 Jun;30(6):589-607.

PMID:
10923861
[PubMed - indexed for MEDLINE]
5.

Effect of phenobarbital and other model inducers on cytochrome P450 isoenzymes in primary culture of dog hepatocytes.

Nishibe Y, Hirata M.

Xenobiotica. 1993 Jun;23(6):681-92.

PMID:
8212741
[PubMed - indexed for MEDLINE]
6.

Suppression of cytochrome P450- and UDP glucuronosyl transferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes.

Monshouwer M, Witkamp RF, Nujmeijer SM, Van Amsterdam JG, Van Miert AS.

Toxicol Appl Pharmacol. 1996 Apr;137(2):237-44.

PMID:
8661349
[PubMed - indexed for MEDLINE]
7.

Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture.

Dickmann LJ, Patel SK, Rock DA, Wienkers LC, Slatter JG.

Drug Metab Dispos. 2011 Aug;39(8):1415-22. doi: 10.1124/dmd.111.038679. Epub 2011 May 9.

PMID:
21555507
[PubMed - indexed for MEDLINE]
Free Article
8.

Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of beta-naphthoflavone, phenobarbital and dexamethasone on cytochrome P450 isoforms expression and on glycogen storage.

Lupp A, Lucas N, Lindström-Seppa P, Koponen K, Hänninen O, Danz M, Klinger W.

Exp Toxicol Pathol. 1998 Jun;50(3):173-83.

PMID:
9681647
[PubMed - indexed for MEDLINE]
9.

A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin.

Zhang JG, Ho T, Callendrello AL, Crespi CL, Stresser DM.

Drug Metab Lett. 2010 Dec;4(4):185-94.

PMID:
20583967
[PubMed - indexed for MEDLINE]
10.

Differential effect of cytokines on the phenobarbital or 3-methylcholanthrene induction of P450 mediated monooxygenase activity in cultured rat hepatocytes.

Clark MA, Bing BA, Gottschall PE, Williams JF.

Biochem Pharmacol. 1995 Jan 6;49(1):97-104.

PMID:
7840789
[PubMed - indexed for MEDLINE]
11.

Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes.

Runge D, Köhler C, Kostrubsky VE, Jäger D, Lehmann T, Runge DM, May U, Stolz DB, Strom SC, Fleig WE, Michalopoulos GK.

Biochem Biophys Res Commun. 2000 Jun 24;273(1):333-41.

PMID:
10873607
[PubMed - indexed for MEDLINE]
13.

Glucocorticoid-dependent induction of interleukin-6 receptor expression in human hepatocytes facilitates interleukin-6 stimulation of amino acid transport.

Fischer CP, Bode BP, Takahashi K, Tanabe KK, Souba WW.

Ann Surg. 1996 May;223(5):610-8; discussion 618-9.

PMID:
8651752
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

In vitro inhibition and induction of human liver cytochrome p450 enzymes by milnacipran.

Paris BL, Ogilvie BW, Scheinkoenig JA, Ndikum-Moffor F, Gibson R, Parkinson A.

Drug Metab Dispos. 2009 Oct;37(10):2045-54. doi: 10.1124/dmd.109.028274. Epub 2009 Jul 16.

PMID:
19608694
[PubMed - indexed for MEDLINE]
Free Article
15.

The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.

Parkinson A, Mudra DR, Johnson C, Dwyer A, Carroll KM.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):193-209. Review.

PMID:
15364537
[PubMed - indexed for MEDLINE]
16.

Clinical versatility of porcine hepatocytes in the light of interspecies differences in cytochrome P450 regulation and expression.

Kleine M, Schrem H, Borlak J, Klempnauer J.

Xenotransplantation. 2008 Jul-Aug;15(4):208-17. doi: 10.1111/j.1399-3089.2008.00478.x.

PMID:
18957043
[PubMed - indexed for MEDLINE]
18.

Cryopreserved human hepatocytes as alternative in vitro model for cytochrome p450 induction studies.

Garcia M, Rager J, Wang Q, Strab R, Hidalgo IJ, Owen A, Li J.

In Vitro Cell Dev Biol Anim. 2003 Jul-Aug;39(7):283-7.

PMID:
14599235
[PubMed - indexed for MEDLINE]
19.

The cytotoxicity of mitomycin C and adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes.

Goeptar AR, te Koppele JM, Glatt HR, Groot EJ, Seidel A, Barrenscheen M, Wölfel C, Doehmer J, Vermeulen NP.

Chem Biol Interact. 1995 Jul 14;97(2):149-68.

PMID:
7606813
[PubMed - indexed for MEDLINE]
20.

Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.

Aitken AE, Morgan ET.

Drug Metab Dispos. 2007 Sep;35(9):1687-93. Epub 2007 Jun 18.

PMID:
17576808
[PubMed - indexed for MEDLINE]
Free PMC Article

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