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Results: 1 to 20 of 104

1.

The immunobiology and pathophysiology of primary biliary cirrhosis.

Hirschfield GM, Gershwin ME.

Annu Rev Pathol. 2013 Jan 24;8:303-30. doi: 10.1146/annurev-pathol-020712-164014. Review.

PMID:
23347352
[PubMed - indexed for MEDLINE]
2.

Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice.

Oertelt S, Lian ZX, Cheng CM, Chuang YH, Padgett KA, He XS, Ridgway WM, Ansari AA, Coppel RL, Li MO, Flavell RA, Kronenberg M, Mackay IR, Gershwin ME.

J Immunol. 2006 Aug 1;177(3):1655-60.

PMID:
16849474
[PubMed - indexed for MEDLINE]
Free Article
3.

Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis.

Nishio A, Van de Water J, Leung PS, Joplin R, Neuberger JM, Lake J, Björkland A, Tötterman TH, Peters M, Worman HJ, Ansari AA, Coppel RL, Gershwin ME.

Hepatology. 1997 May;25(5):1085-9.

PMID:
9141421
[PubMed - indexed for MEDLINE]
4.

Primary biliary cirrhosis: an orchestrated immune response against epithelial cells.

Gershwin ME, Ansari AA, Mackay IR, Nakanuma Y, Nishio A, Rowley MJ, Coppel RL.

Immunol Rev. 2000 Apr;174:210-25. Review.

PMID:
10807518
[PubMed - indexed for MEDLINE]
5.

In situ nucleic acid detection of PDC-E2, BCOADC-E2, OGDC-E2, PDC-E1alpha, BCOADC-E1alpha, OGDC-E1, and the E3 binding protein (protein X) in primary biliary cirrhosis.

Harada K, Sudo Y, Kono N, Ozaki S, Tsuneyama K, Gershwin ME, Nakanuma Y.

Hepatology. 1999 Jul;30(1):36-45.

PMID:
10385636
[PubMed - indexed for MEDLINE]
6.

Apotopes and the biliary specificity of primary biliary cirrhosis.

Lleo A, Selmi C, Invernizzi P, Podda M, Coppel RL, Mackay IR, Gores GJ, Ansari AA, Van de Water J, Gershwin ME.

Hepatology. 2009 Mar;49(3):871-9. doi: 10.1002/hep.22736.

PMID:
19185000
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis.

Irie J, Wu Y, Wicker LS, Rainbow D, Nalesnik MA, Hirsch R, Peterson LB, Leung PS, Cheng C, Mackay IR, Gershwin ME, Ridgway WM.

J Exp Med. 2006 May 15;203(5):1209-19. Epub 2006 Apr 24.

PMID:
16636131
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis.

Kita H, Matsumura S, He XS, Ansari AA, Lian ZX, Van de Water J, Coppel RL, Kaplan MM, Gershwin ME.

J Clin Invest. 2002 May;109(9):1231-40.

PMID:
11994412
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.

Shimoda S, Van de Water J, Ansari A, Nakamura M, Ishibashi H, Coppel RL, Lake J, Keeffe EB, Roche TE, Gershwin ME.

J Clin Invest. 1998 Nov 15;102(10):1831-40.

PMID:
9819369
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Use of a designer triple expression hybrid clone for three different lipoyl domain for the detection of antimitochondrial autoantibodies.

Moteki S, Leung PS, Coppel RL, Dickson ER, Kaplan MM, Munoz S, Gershwin ME.

Hepatology. 1996 Jul;24(1):97-103.

PMID:
8707289
[PubMed - indexed for MEDLINE]
11.

Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis.

Bassendine MF, Jones DE, Yeaman SJ.

Semin Liver Dis. 1997 Feb;17(1):49-60. Review.

PMID:
9089910
[PubMed - indexed for MEDLINE]
12.

Evidence for the targeting by 2-oxo-dehydrogenase enzymes in the T cell response of primary biliary cirrhosis.

Van de Water J, Ansari AA, Surh CD, Coppel R, Roche T, Bonkovsky H, Kaplan M, Gershwin ME.

J Immunol. 1991 Jan 1;146(1):89-94.

PMID:
1984455
[PubMed - indexed for MEDLINE]
13.

Heterogeneity of combinatorial human autoantibodies against PDC-E2 and biliary epithelial cells in patients with primary biliary cirrhosis.

Cha S, Leung PS, Coppel RL, Van de Water J, Ansari AA, Gershwin ME.

Hepatology. 1994 Sep;20(3):574-83.

PMID:
7521314
[PubMed - indexed for MEDLINE]
14.

Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis.

Lleo A, Bowlus CL, Yang GX, Invernizzi P, Podda M, Van de Water J, Ansari AA, Coppel RL, Worman HJ, Gores GJ, Gershwin ME.

Hepatology. 2010 Sep;52(3):987-98. doi: 10.1002/hep.23783.

PMID:
20568301
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

CD4 T-cell autoreactivity to the mitochondrial autoantigen PDC-E2 in AMA-negative primary biliary cirrhosis.

Shimoda S, Miyakawa H, Nakamura M, Ishibashi H, Kikuchi K, Kita H, Niiro H, Arinobu Y, Ono N, Mackay IR, Gershwin ME, Akashi K.

J Autoimmun. 2008 Sep;31(2):110-5. doi: 10.1016/j.jaut.2008.05.003. Epub 2008 Jul 21.

PMID:
18644699
[PubMed - indexed for MEDLINE]
16.

Autoreactive responses to pyruvate dehydrogenase complex in the pathogenesis of primary biliary cirrhosis.

Yeaman SJ, Kirby JA, Jones DE.

Immunol Rev. 2000 Apr;174:238-49. Review.

PMID:
10807520
[PubMed - indexed for MEDLINE]
17.

The multi-hit hypothesis of primary biliary cirrhosis: polyinosinic-polycytidylic acid (poly I:C) and murine autoimmune cholangitis.

Ambrosini YM, Yang GX, Zhang W, Tsuda M, Shu S, Tsuneyama K, Leung PS, Ansari AA, Coppel RL, Gershwin ME.

Clin Exp Immunol. 2011 Oct;166(1):110-20. doi: 10.1111/j.1365-2249.2011.04453.x.

PMID:
21910728
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Ductular expression of autoantigens in primary biliary cirrhosis.

Joplin R, Gershwin ME.

Semin Liver Dis. 1997 May;17(2):97-103. Review.

PMID:
9170196
[PubMed - indexed for MEDLINE]
19.

Etiopathogenesis of primary biliary cirrhosis.

Lleo A, Invernizzi P, Mackay IR, Prince H, Zhong RQ, Gershwin ME.

World J Gastroenterol. 2008 Jun 7;14(21):3328-37. Review.

PMID:
18528930
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Phenotypical and functional alterations of CD8 regulatory T cells in primary biliary cirrhosis.

Bernuzzi F, Fenoglio D, Battaglia F, Fravega M, Gershwin ME, Indiveri F, Ansari AA, Podda M, Invernizzi P, Filaci G.

J Autoimmun. 2010 Nov;35(3):176-80. doi: 10.1016/j.jaut.2010.06.004. Epub 2010 Jul 16.

PMID:
20638239
[PubMed - indexed for MEDLINE]
Free PMC Article

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