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Items: 1 to 20 of 109

1.

Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic.

McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3477-82. doi: 10.1073/pnas.1221924110. Epub 2013 Jan 23.

2.

Use of antimicrobial peptides against microbial biofilms: advantages and limits.

Batoni G, Maisetta G, Brancatisano FL, Esin S, Campa M.

Curr Med Chem. 2011;18(2):256-79. Review.

PMID:
21110801
3.

Recent development of small antimicrobial peptidomimetics.

Niu Y, Wang RE, Wu H, Cai J.

Future Med Chem. 2012 Sep;4(14):1853-62. doi: 10.4155/fmc.12.111. Review.

PMID:
23043481
4.

Non-hemolytic α-AApeptides as antimicrobial peptidomimetics.

Padhee S, Hu Y, Niu Y, Bai G, Wu H, Costanza F, West L, Harrington L, Shaw LN, Cao C, Cai J.

Chem Commun (Camb). 2011 Sep 14;47(34):9729-31. doi: 10.1039/c1cc13684d. Epub 2011 Jul 21.

PMID:
21779608
5.

Synthesis of short cationic antimicrobial peptidomimetics containing arginine analogues.

Baldassarre L, Pinnen F, Cornacchia C, Fornasari E, Cellini L, Baffoni M, Cacciatore I.

J Pept Sci. 2012 Sep;18(9):567-78. doi: 10.1002/psc.2435. Epub 2012 Jul 17.

PMID:
22807132
6.

Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes.

Andreev K, Bianchi C, Laursen JS, Citterio L, Hein-Kristensen L, Gram L, Kuzmenko I, Olsen CA, Gidalevitz D.

Biochim Biophys Acta. 2014 Oct;1838(10):2492-502. doi: 10.1016/j.bbamem.2014.05.022. Epub 2014 May 28.

7.

An antimicrobial peptidomimetic induces Mucorales cell death through mitochondria-mediated apoptosis.

Barbu EM, Shirazi F, McGrath DM, Albert N, Sidman RL, Pasqualini R, Arap W, Kontoyiannis DP.

PLoS One. 2013 Oct 3;8(10):e76981. doi: 10.1371/journal.pone.0076981. eCollection 2013.

8.

Characterization of a proteolytically stable multifunctional host defense peptidomimetic.

Jahnsen RD, Haney EF, Franzyk H, Hancock RE.

Chem Biol. 2013 Oct 24;20(10):1286-95. doi: 10.1016/j.chembiol.2013.09.007. Epub 2013 Oct 10.

9.

A synthetic antimicrobial peptidomimetic (LTX 109): stereochemical impact on membrane disruption.

Isaksson J, Brandsdal BO, Engqvist M, Flaten GE, Svendsen JS, Stensen W.

J Med Chem. 2011 Aug 25;54(16):5786-95. doi: 10.1021/jm200450h. Epub 2011 Jul 26.

PMID:
21732630
10.

Ceragenins (cationic steroid compounds), a novel class of antimicrobial agents.

Epand RM, Epand RF, Savage PB.

Drug News Perspect. 2008 Jul-Aug;21(6):307-11. doi: 10.1358/dnp.2008.21.6.1246829. Review.

PMID:
18836587
11.

Antibacterial evaluation of structurally amphipathic, membrane active small cationic peptidomimetics: synthesized by incorporating 3-amino benzoic acid as peptidomimetic element.

Lohan S, Cameotra SS, Bisht GS.

Eur J Med Chem. 2014 Aug 18;83:102-15. doi: 10.1016/j.ejmech.2014.06.023. Epub 2014 Jun 12.

PMID:
24953028
12.

Lipo-γ-AApeptides as a new class of potent and broad-spectrum antimicrobial agents.

Niu Y, Padhee S, Wu H, Bai G, Qiao Q, Hu Y, Harrington L, Burda WN, Shaw LN, Cao C, Cai J.

J Med Chem. 2012 Apr 26;55(8):4003-9. doi: 10.1021/jm300274p. Epub 2012 Apr 17.

PMID:
22475244
13.

Discovery of novel histidine-derived lipo-amino acids: applied in the synthesis of ultra-short antimicrobial peptidomimetics having potent antimicrobial activity, salt resistance and protease stability.

Ahn M, Murugan RN, Jacob B, Hyun JK, Cheong C, Hwang E, Park HN, Seo JH, Srinivasrao G, Lee KS, Shin SY, Bang JK.

Eur J Med Chem. 2013 Oct;68:10-8. doi: 10.1016/j.ejmech.2013.07.008. Epub 2013 Jul 26.

PMID:
23933046
14.

The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses.

Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J.

Chembiochem. 2014 Mar 21;15(5):688-94.

15.

Antimicrobial peptide pleurocidin synergizes with antibiotics through hydroxyl radical formation and membrane damage, and exerts antibiofilm activity.

Choi H, Lee DG.

Biochim Biophys Acta. 2012 Dec;1820(12):1831-8. doi: 10.1016/j.bbagen.2012.08.012. Epub 2012 Aug 16.

PMID:
22921812
16.

Antimicrobial γ-AApeptides (WO2013112548): a patent evaluation.

Teng P, Wu H, Lin L, Cai J.

Expert Opin Ther Pat. 2015 Jan;25(1):111-8. doi: 10.1517/13543776.2014.973855. Epub 2014 Oct 21. Review.

PMID:
25331592
17.

AApeptides as a new class of antimicrobial agents.

Niu Y, Wu H, Li Y, Hu Y, Padhee S, Li Q, Cao C, Cai J.

Org Biomol Chem. 2013 Jul 14;11(26):4283-90. doi: 10.1039/c3ob40444g. Epub 2013 May 31. Review.

PMID:
23722277
18.

Antimicrobial peptides incorporating non-natural amino acids as agents for plant protection.

Ng-Choi I, Soler M, Güell I, Badosa E, Cabrefiga J, Bardaji E, Montesinos E, Planas M, Feliu L.

Protein Pept Lett. 2014 Apr;21(4):357-67. Review.

PMID:
24164267
19.

Mechanism of action of puroindoline derived tryptophan-rich antimicrobial peptides.

Haney EF, Petersen AP, Lau CK, Jing W, Storey DG, Vogel HJ.

Biochim Biophys Acta. 2013 Aug;1828(8):1802-13. doi: 10.1016/j.bbamem.2013.03.023. Epub 2013 Apr 2.

20.

Learning from cancer how to defeat bacteria.

Onuchic JN, Jennings PA, Ben-Jacob E.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3212-3. doi: 10.1073/pnas.1222882110. Epub 2013 Feb 13. No abstract available.

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